LymeNet Flash: Will be starting Mepron combo today or tomorrow have some ?'s

This is topic Will be starting Mepron combo today or tomorrow have some ?'s in forum Medical Questions at LymeNet Flash.

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Posted by mimi (Member # 6680) on :

If I start this what should I expect? Zith-clindimyocin- mepron

Posted by minoucat (Member # 5175) on :

mimi -- when I started babs tx, I had about 4 months of feeling pretty miserable. Massive headache, extreme irritability, very achey legs.

The good news is, it was completely worth it. I did the mepron/zith/artemesinin tx, and have been babs-free for 9 mo so far.

Take very good care of you liver on this protocol -- we did liver flushes and pulsed Super Milk Thistle (there is other good stuff, too). I felt noticeably better after the liver flushes.

Posted by trails (Member # 1620) on :

BUT be careful of milk thistle with mepron! It lowers the blood levels of mepron! Please join the merpon buddies and keep us updated on your healing journey! http://flash.lymenet.org/ubb/Forum1/HTML/034710.html
Welcome to the golden girls of mepron!
Trails

Below I copied the info from this website: http://www.catie.ca/supple-e.nsf/0/7b09aa55a412896c85256c6e0070bf60?OpenDocument

2. Milk thistle and other medications
Below is a short list of some other medications that are processed through the CYP3A4 enzyme. Based on the effect of milk thistle on liver enzymes in the lab, it is possible that levels of these medications may increase if taken by people who are also using milk thistle. This list is not exhaustive:

* methadone
* heart drugs - Tambocor (flecainide), Rythmol (propafenone)
* antibiotics - erythromycin, rifampin
* anti-seizure drugs - carbamazepine (Tegretol)
* antidepressants - Zyban/Wellbutrin (bupropion), Paxil (paroxetine), Prozac (fluoxetine), Luvox (fluvoxetine). Serzone (nefazodone), Zoloft (sertraline), Effexor (venlafaxine)
* St. John's wort
* antihistamines - Hismanal (astemizole), Seldane (terfenadine)
* antifungals - itraconazole (Sporanox), ketoconazole (Nizoral)
* gastrointestinal motility agents - Prepulsid (Cisapride)
* ergot drugs - Ergonovine, Ergomar (ergotamine)
* anti-psychotics - Clozaril (clozapine), Orap (pimozide)
* sedatives/sleeping pills - Ambien (zolpidem), Halcion (triazolam), Versed (midazolam)
* erectile dysfunction drugs - Viagra (sildenafil)
* street drugs - ecstasy (MDMA)
* lipid-lowering drugs (statins) - Lescol (fluvastatin), Mevacor (lovastatin), Pravachol (pravastatin), Zocor (simvastatin)
* transplant drugs - cyclosporine (Neoral, Sandimmune), ProGraf (tacrolimus)

Milk thistle also has the potential to lower levels of the following drugs in the blood:

* anti-parasite drugs - Mepron (atovaquone)
* sedatives/sleeping pills - Ativan (lorazepam)
* hormones - estrogen

Posted by mimi (Member # 6680) on :

Thanks for the info. and kind welcome to the golden girls but I have had a set back and will not be starting after all at least not yet will have to wait a few more weeks maybe. Anyway I will be reading and cheering you all on until I begin. Where can I find artemisinin???
Thanks,
mimi