LymeNet Home LymeNet Home Page LymeNet Flash Discussion LymeNet Support Group Database LymeNet Literature Library LymeNet Legal Resources LymeNet Medical & Scientific Abstract Database LymeNet Newsletter Home Page LymeNet Recommended Books LymeNet Tick Pictures Search The LymeNet Site LymeNet Links LymeNet Frequently Asked Questions About The Lyme Disease Network LymeNet Menu

LymeNet on Facebook

LymeNet on Twitter




The Lyme Disease Network receives a commission from Amazon.com for each purchase originating from this site.

When purchasing from Amazon.com, please
click here first.

Thank you.

LymeNet Flash Discussion
Dedicated to the Bachmann Family

LymeNet needs your help:
LymeNet 2020 fund drive


The Lyme Disease Network is a non-profit organization funded by individual donations.

LymeNet Flash Post New Topic  New Poll  Post A Reply
my profile | directory login | register | search | faq | forum home

  next oldest topic   next newest topic
» LymeNet Flash » Questions and Discussion » Medical Questions » Dimethylglycine & high B12 B complex?

 - UBBFriend: Email this page to someone!    
Author Topic: Dimethylglycine & high B12 B complex?
welcome
LymeNet Contributor
Member # 7953

Icon 1 posted      Profile for welcome     Send New Private Message       Edit/Delete Post   Reply With Quote 
Anyone have experience with this "protocol"?
Posts: 294 | From nevada | Registered: Sep 2005  |  IP: Logged | Report this post to a Moderator
Marnie
Frequent Contributor (5K+ posts)
Member # 773

Icon 1 posted      Profile for Marnie     Send New Private Message       Edit/Delete Post   Reply With Quote 
I wish I was a chemist...!

What is it about "ethyl"? In many drugs (abxs)...in acetylcholine and melatonin...

PKC inhibitors...protein kinase C inhibitors...some inhibit acetylcholine release. They "compete" with ATP and most Mg is bound to ATP. They cause cell death. Bb has a PKC inhibitor.

If we block angiotensin II with Mg doses or Benicar this looks to release NO (research ethyl and NO - nitric oxide) which releases acetylcholine.

Acetylcholine is needed for REM sleep...when we MAKE proteins...NREM sleep needs melatonin...NREM must precede REM...

Are you a chemist? Know one? Yo...pq...calling for help....

Theoretically...chemically...will it work?

Posts: 9481 | From Sunshine State | Registered: Mar 2001  |  IP: Logged | Report this post to a Moderator
seibertneurolyme
Frequent Contributor (5K+ posts)
Member # 6416

Icon 1 posted      Profile for seibertneurolyme     Send New Private Message       Edit/Delete Post   Reply With Quote 
This would probably lower your homocysteine level and that's about all. Would probably increase energy level as well, but in my opinion would have no effect on Lyme or other coinfections.

Research methylation which is one of the detox pathways. Great Smokies does a genetic test for defects in this pathway. Hubby has this genetic defect.

Uses Sam-e, high dose folinic acid (a form of folic acid) and B12 injections to overcome genetic defect. Tried other nutritional combos, but this works best for him.

Bea Seibert

Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004  |  IP: Logged | Report this post to a Moderator
pq
Frequent Contributor (1K+ posts)
Member # 6886

Icon 1 posted      Profile for pq     Send New Private Message       Edit/Delete Post   Reply With Quote 
welcome,

what is this protocol, and what is it purported to do?

Posts: 2708 | Registered: Feb 2005  |  IP: Logged | Report this post to a Moderator
welcome
LymeNet Contributor
Member # 7953

Icon 1 posted      Profile for welcome     Send New Private Message       Edit/Delete Post   Reply With Quote 
Heard it described on another board as some kind of protocol (or maybe part of protocol) recommended by some LLMD (back east i think).

My impression was that by breaking a significant portion of the toxin cycle the body would begin to create an inhospitable enviroment for BB, which in turn amplified other treatments including ABX.

I've heard of (and followed) this strategy for Candida toxins with Molybdenum.

What do you think chemically about the end result biolgically of such a supplement combination?

Posts: 294 | From nevada | Registered: Sep 2005  |  IP: Logged | Report this post to a Moderator
pq
Frequent Contributor (1K+ posts)
Member # 6886

Icon 1 posted      Profile for pq     Send New Private Message       Edit/Delete Post   Reply With Quote 
welcome,


while i haven't looked deeply into glycine(except many moons ago),my guess that the dimethylglycine would be functioning in part as a methyl group( -CH3) donor. 'di-' = two, methyl = CH3 thusly, and hence two methyl groups of atoms are given up to something.
one function of the B12 may have a similar function as mentioned above with the dimethyl glycine,either in donating, accepting, or switching atom(s) from one part of a molecule to another part of the same molecule, or other molecules.

I believe glycine, itself, is used by the body for mineral transport from the gut. However, certain infectious organisms also use this amino acid, and may be fueled by this. i don't know if this would be the case with the 2 methyl groups hooked up to it.

the molybdenum, with its many oxidation states, has a role in liver detox.

gotta keep this short, as i'm too Sx-o-matic, right now.

the site for townsend letter for doctors and patients, garynull.com, thorne.com, and lef.org should have some real interesting information on dimethylglycine, and molybdenum.

Posts: 2708 | Registered: Feb 2005  |  IP: Logged | Report this post to a Moderator
seibertneurolyme
Frequent Contributor (5K+ posts)
Member # 6416

Icon 1 posted      Profile for seibertneurolyme     Send New Private Message       Edit/Delete Post   Reply With Quote 
Found an interesting website -- haven't had time to read and absorb info but wanted to pass on the link.

Mostly discusses AIDS, CFS, HHV6 and Lyme and various immune modulators -- primarily herbs and nutrients.

Such things as transfer factor, Venus flytrap and the DMG protocol asked about here.

http://www.bulkmsm.com/DMG/web12.htm

See Vol.2 No.8 August 1, 1999 -- Case No.7 for DMG info.

Bea Seibert

Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004  |  IP: Logged | Report this post to a Moderator
welcome
LymeNet Contributor
Member # 7953

Icon 1 posted      Profile for welcome     Send New Private Message       Edit/Delete Post   Reply With Quote 
quote:
Originally posted by seibertneurolyme:
Found an interesting website -- haven't had time to read and absorb info but wanted to pass on the link.

Mostly discusses AIDS, CFS, HHV6 and Lyme and various immune modulators -- primarily herbs and nutrients.

Such things as transfer factor, Venus flytrap and the DMG protocol asked about here.

http://www.bulkmsm.com/DMG/web12.htm

See Vol.2 No.8 August 1, 1999 -- Case No.7 for DMG info.

Bea Seibert

I sent a message to Marnie listing the compounds found in it to see what her esteemed evaluation would be in regards to lymies using it.

A copy of the list of compounds in VFT follows:

Droserone:1, 4-Naphthoquinone derivate; Spasmolytic, coughblocking, antibiotic properties.

Hydroplumbagin:Hydroplumbagin-4-O-B-glucopyranoside; Immune modulation, stimulation.

Formic acid: Mono carbon acid; Antiseptic properties.

Quercetin (Flavonoid): Quercetin-3-O-galactoside, -3-O-glucoside, -3-0-rutinoside; Via a specific pathway in the human body, these components contribute to the regulation of immune modulation and stimulation, support the circulatory system and maximize the efficiency of heart function.

Myricetin (Flavonoid): Myricetin-OH; Same properties and actions as Quercetin.

Gallic acid derivates: Cholic acid, deoxycholic acid and chenodeoxycholic acid; Aid in emulsification of fat by supporting the efficacy of lipases, immunestimulative action aids chronic conditions.

Amino Acids

Arginine:(S)-2-amino-5-guanidinopentane acid; Essential in childhood, plays an important role in the uric acid cycle, liver-protective, turns into the homologue of lysine which is essential to mitochondrial function and to the production of creatine and putrescine, the pre-stage of spermine and spermidine which stabilize the DNA structure in human spermatozoa.

Asparagine: Aminosuccinamic acid; Amino donator, proteinogen amino acid.

Threonine:(2S,3R)-2-amino-3-hydroxybutane acid; Essential human nutrient; metabolizes to ketobutyrate and glycine; regulates cholesterol; protein element.

Glutamine:(S)-2-amino-glutaric acid; Donator of amino groups; detoxifying end product of ammonia metabolism; source of gamma amino-butyrate (neurotransmitter); acceptor molecule of ammonia detoxification.

Alanine:(S)-2-amino acid; Key function as most important glucogenic amino acid, it is essential to catalyze and block harmful enzymes.

Cysteine:(R9)-2-amino-3-mercaptopropionic acid; Causes acid urine, source of sulfate; high concentration in the brain; essential for fetus and premature children.

Serine:(S9)-2-amino-3-hydroxypropionic acid; Glycoproteins; component of immune globulins (antibodies).

Histidine:(S)-2-amino-3-imidazol-4-yl-propan acid; Metabolizes to histamine.

Proteases:Enzymes that split proteins and peptides, protein kinases that block protein synthesis.

Lipopolysaccharides:Originate from biosynthesis of polysaccharides which are bound to lipids; Retinol has similar characteristics.

Posts: 294 | From nevada | Registered: Sep 2005  |  IP: Logged | Report this post to a Moderator
welcome
LymeNet Contributor
Member # 7953

Icon 1 posted      Profile for welcome     Send New Private Message       Edit/Delete Post   Reply With Quote 
"The strategy of adding Methyl Donors and/or Methyl-B12 is based on Japanese research that Methyl-B12 increases CD8 cytotoxic lymphocyte activity (CTL's) and Natural Killer cell function. An overwhelming amount of published scientific research indicates that CD8 CTL's can destroy the virus infected cells. Methyl B12 should be one on the must do list of everyone with chronic immune dysfunction whether it is caused by HIV, HHV-6 or other conditions like CFIDS, Lyme, cancer, candidiasis and any condition where body temperature is below normal and infections persist"

Thanks seibertneurolyme

Posts: 294 | From nevada | Registered: Sep 2005  |  IP: Logged | Report this post to a Moderator
   

Quick Reply
Message:

HTML is not enabled.
UBB Code� is enabled.

Instant Graemlins
   


Post New Topic  New Poll  Post A Reply Close Topic   Feature Topic   Move Topic   Delete Topic next oldest topic   next newest topic
 - Printer-friendly view of this topic
Hop To:


Contact Us | LymeNet home page | Privacy Statement

Powered by UBB.classic™ 6.7.3


The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:

The Lyme Disease Network of New Jersey
907 Pebble Creek Court, Pennington, NJ 08534 USA


| Flash Discussion | Support Groups | On-Line Library
Legal Resources | Medical Abstracts | Newsletter | Books
Pictures | Site Search | Links | Help/Questions
About LymeNet | Contact Us

© 1993-2020 The Lyme Disease Network of New Jersey, Inc.
All Rights Reserved.
Use of the LymeNet Site is subject to Terms and Conditions.