posted
My freind has elevated psa. Could this be caused by inflamation from abx killing lyme/bart/babs? thanx for any theories. kt
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mlkeen
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It could be. I was reading about the prostate gland last week, because my dad's PSA is elevated.
The prostate acts as a filter to keep toxins from sperm so is inclined to be full of all kinds of nasty stuff. Add lyne, dead or alive, to the mix and I would think inflammation is certainly an option.
I wonder if the is any of detox that addresses this area?
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posted
Thanx mlkeen, makes sense...I know the p stands for prostate, but what does sa stand for I wonder?
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mlkeen
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prostate specific antigen
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"Could this be caused by inflamation from abx killing lyme/bart/babs?" I doubt it since it is only measuring a specific antigen that is a cancer marker. It shouldn't have anything to do with lyme or pathogen die off from abx. It might depend also on how much it is elevated. My PSA hasn't been effected by abx Tx at all.
-------------------- You're only a failure when you stop trying. Posts: 945 | From U.S | Registered: Oct 2004
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GiGi
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Yes, the prostate is a collection place of toxins, specifically heavy metals/mercury. Same holds true for female ovarian cysts -- the research is there definitely. Often things go back to normal once a serious elimination and detox program is undertaken.
Dr. K. mentions it in most seminars when he teaches Neural Therapy. It is usually part of such a detox program that is combined with neural therapy, etc. I have had treatments in that regard -- to clear out the pelvic area of heavy metals. It is a favorite place - gravity - . Undoubtedly Lyme bacteria is part of it since they hang out in these heavy metal contaminated areas.
Take care.
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posted
Thanks gigi, That's very interesting in that you could almost apply the inflamation et al explanation to all sorts of "cancer markers".Certainly makes conventional cancer treatments seem counter productive.
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Marnie
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TNF alpha and angiotensin II are PROTEINS (both helpful and destructive). Hormones and enzymes are PROTEINS... So are immunoglobulins/antibodies...antigens...PROTEINS.
The cancer "markers" CEA, PSA...are PROTEINS.
The body is trying to eliminate a "problem" via the proteins. It uses various proteins (acidic, neg. charge) to do this.
Mg (and Ca) is needed to MAKE the proteins...all of them.
We MAKE many proteins during REM (rapid eye movement) sleep which is when we need acetylcholine.
But Bb is destroying acetylcholine via an enzyme breaking it down because it wants choline to make it's own cholesterol.
Mg levels drop fast in this disease because Bb has a PKC (protein kinase C) inhibitor. When the body encounters this...Mg drops a lot, fast.
Various PKC inhibitors are "competitive". Bb's PKC inhibitor appears to compete with Mg-ATP. Most of Mg is bound to ATP. The inhibitors destroy cells. A man-made PKC inhibitor is Tamoxifin...to destroy estrogen dependent cancer cells.
Mg is needed to INactivate PFK (Bb is PFK dependent) and to INactivate HMG CoA reductase. Inactivating these enzymes puts the brakes on the glycolysis AND cholesterol pathways simultaneously. Our body is trying to fight. It recognizes a major attacker.
When my son was very sick (food poisoning) he dumped cholesterol...it dropped to 86 (not a typo) and his folic acid level soared. This was his own body trying to PROTECT him. His body became very acidic. His minerals (tested) dropped too. The combo...lots of acids + little mineral/glycogen yields hydrogen. We need to make a LOT of hydrogen constantly to stay healthy...to fight the pathogens.
Low cholesterol levels are a marker for bowel cancer. Go to pubmed (www.pubmed.com) and type in: "low cholesterol cancer". Cancer cells follow the glycolysis pathway.
The way our NK...natural killer cells work is they spot a precancerous cell (ususally about 4 per day) and "squirt" it with a neg. charge (very simplified explanation).
However, our NK cells need Ca and Mg...in adequate amts...balanced... to work. This is how (technically speaking):
Antibody Dependent Killer (K) and Natural Killer (NK) cells (ASCC) kill by extracellular cytotoxicity by binding to a target cell and secreting cytolysins which unidirectionally kill the target cell. Once the target is bound by an NKAR and no NKIR is activated, the cytotoxic reaction occurs. The interaction of cell adhesion molecules between NK and the target cell may tighten the attachment.
The first step is a MAGNESIUM DEPENDENT movement of the cytoplasmix organelles (Golgi and granules) of the NK cell to face the target cell. The secretion of the granule contents into the intercellular space is a CALCIUM DEPENDENT step that results in the preferential insertion of perforin pores into the target cell membrane.
Extremely simplified: Mg levels drop, Ca rises (both of these are minerals) then TNF alpha rises and angiotensin II rises (these are proteins).
If we go back to the beginning...Mg levels drop...and restore those levels...we should be able to stop the subsequent things from happening (Ca rising, TNF alpha and angiotensin II kicking in).
Your friend's body is trying to fight by elevating a specific protein that is a marker for prostate cancer.
Magnesium and BPH - Lyme Symptom #10
``Some doctors recommend a veritable smorgasbord of nutrients to treat benign prostatic hyperplasia. One of their recommended supplements is...magnesium.
`I'm well aware that there is nothing most doctors would call evidence that these nutrients help BPH,' he says. `In my own experience, however, men who eat healthy diets and take these supplements have all-around better health and are less likely to require surgery.'' (5)
``Dr. Favier gives a Dr. Stora credit for being the first to discover magnesium chloride as an effective agent in treating urinary troubles of prostate origin. He informed the Medical Academy of France of it, on March 18, 1930. Eight days later, Dr. Pierre Delbet submitted a report showing the same results with magnesium chloride.
When Dr. Stora spoke about his results to Favier, the author of the book we are discussing, Favier began to make inquiries among his physician friends ... He found that they were all taking magnesium chloride. To his surprise he found that four out of five of them had been disturbed by difficulties in urinating, especially at night. And all of them, after taking the magnesium tablets, found that their nocturnal urinating troubles diminished or disappeared.''
Valletta cured invasive bowel cancer using Mg pyrophosphate and sublingual B6 and the Romanian doctors (from a CANCER hospital)cured lyme patients when they restored the "significant drop" in Mg levels...think about that. Can restoring Mg levels cure lyme AND cancer? Sorta looks that way.
Hydrogen...LOTS needed. Mg + acids.
P.S. To carry hydrogen INTO the cells...to heal...need CoQ10 (which we normally make when we EXERCISE) IF we have the nutrients to make this enzyme...Mg and B6.
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Here is a thing from National Cancer Institute. Among other things, it says the PSA test can be grossly inaccurate.
------------------------------------------
Researchers Discover Protein Signatures for Prostate Cancer That Could Improve Diagnosis of Early Disease
A new study shows that testing blood samples for antibodies that target prostate cancer cells may help identify patients with early stages of the disease. In the September 22, 2005, issue of New England Journal of Medicine*, researchers report the findings may lead to a new test that could complement the prostate specific antigen (PSA) test in detecting early stage prostate cancer. The study was supported by the Early Detection Research Network (EDRN), an initiative of the National Cancer Institute (NCI), part of the National Institutes of Health.
Previous studies have found that men with normal blood levels of PSA (4.0 ng/ml or less) can have prostate cancer**. Furthermore, PSA-based prostate cancer screening has a high rate of false-positive results (up to 80 percent). Therefore, scientists have been looking for additional ways to adequately screen for early disease.
"Using PSA testing alone results in millions of dollars being spent on prostate biopsies due to false-positive results. We don't yet know if our new findings will save lives, but there could be a major cost saving by decreasing the number of prostate biopsies performed every year," said Sudhir Srivastava, Ph.D., chief, Cancer Biomarkers Research Program and director for the EDRN.
The panel of 22 target proteins identified in this study showed an 88.2 percent specificity value for prostate cancer, which indicates the proportion of those tested who did not have cancer and were correctly identified as being free of disease. The test also showed an 81.6 percent sensitivity value, indicating the proportion of those patients with cancer that were correctly diagnosed as having prostate cancer.
Scientists know that cancer patients produce antibodies to proteins, called antigens, which are present on the surface of tumor cells. Antibodies themselves are proteins produced by immune cells to help fight and destroy viruses, bacteria, and other foreign substances that invade the body. As a cancer cell grows, normal antigens can be presented on a cell surface in a different way. The body then recognizes these antigens as foreign and produces antibodies to these cells. These particular antibodies are termed autoantibodies, because they react to a substance produced by the body itself.
"In this study, we took advantage of the body's own immune system as a detector of prostate cancer," said Arul Chinnaiyan, M.D., Ph.D., study leader, University of Michigan Medical School, Ann Arbor. "While the present study focused on the detection of prostate cancer, this general approach has potential to be developed for other cancers, as well as for other human diseases that in some way perturb the immune system."
The use of autoantibody signatures may be more useful in combination with PSA testing in reducing the number of false-negative and false-positive tests obtained than when using PSA testing alone. Statistical analysis of these results shows that the protein panel performed better in distinguishing between prostate cancer patients and controls than the PSA test. The panel of 22 proteins predicted the presence of cancer accurately 92.7 percent of the time, while PSA predicted the presence of cancer only 79.6 percent of the time. The use of autoantibody signatures may be most informative in assessing the need for a biopsy in patients with PSA values of 10ng/ml or less.
"Identification of autoantibodies is an exciting area of research. We are also looking to see if the autoantibodies produced against prostate cancer cells are specific only to this disease," said Srivastava. "Knowledge of whether antibodies are specific to particular organs will be important when considering a design for any new test."
A total of 257 blood samples were tested for novel prostate cancer autoantibodies; blood samples from 119 patients with prostate cancer were studied prior to surgery and 138 samples were from patients without prostate cancer. Among the 22 peptides found, the genes that code four of them were identified: eIF4G1, BRD2, RPL13a, and RPL22***.
Collaborators supported by the EDRN will further analyze the peptide panel test. Both the reproducibility of this study protocol and new blood samples will be used to validate the peptide panel. For clinical application to occur, the test will need to be validated in different populations and at various EDRN testing sites, a process that is being planned.
# # #
For more information about cancer, visit the NCI Web site at http://www.cancer.gov or call NCI's Cancer Information Service at 1-800-4-CANCER (1-800-422-6237).
* Wang X, Yu J, Sreekumar A, Varambally S, Shen R, Giacherio D, Mehra R, Montie JE, Pienta KJ, Sanda MG, Mantoff PW, Rubin MA, Wei JT, Ghosh D, Chinnaiyan AM. Autoantibody Signatures in Prostate Cancer. New England Journal of Medicine, September 22, 2005: 353 (12): 16-27.
** Thompson IM, Pauler DK, Goodman PJ, Tangen CM, Lucia MS, Parnes HL, Minasian LM, Ford LG, Lippman SM, Crawford ED, Crowley JJ, Coltman CA. Prevalence of Prostate Cancer among Men with a Prostate-Specific Antigen Level Less Than or Equal to 4.0 ng per Milliliter. New England Journal of Medicine, May 27, 2004; 350 (22): 2239-2246.
*** eIF4G1 (eukaryotic translation initiation factor 4 gamma 1), BRD2 (bromodomain containing 2), RPL13a (ribosomal protein L13a), and RPL22 (ribosomal protein L22).
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GiGi
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posted
Krazykt, I do not mean to say that conventional cancer treatments would be counterproductive. What I do know (from my involvement with Dr. K. patients) is that many cancer patients have been cured when a thorough detoxification program was part of, a big part of, the cancer treatment. It does not eliminate any conventional possibilities. That's up to the doctor's judgement. But in Dr. K's practice it has been found that a "clean-out" and his approach of "Five Levels of Healing" often is successful. It usually includes the teeth (root canals!!!!! cavitations, amalgam fillings, etc.) It also usually includes addressing electromagnetic exposures and geopathic stress exposures. And of course included are addressing all infections, such as Lyme, viruses, parasites, mold and fungi, on and on.
It is a natural that nutritional deficiencies and the biochemical corrections are always part of the approach.
Take care.
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Marnie, GiGi, Lou...you guys are awesome!! Thanks so much.kt
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Marnie
Frequent Contributor (5K+ posts)
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In the news very recently...might want to pass along to your friend:
Nov. 1, 2005 -- Vitamin D compounds may help slow or prevent prostate cancer, according to a new study. The compounds are "promising" for preventing prostate cancers that are sensitive to male sex hormones (androgen), write the researchers. The study was done on male mice, not people. More work is needed to probe the compound's cancer-fighting potential.
Focusing on Vitamin D People can get vitamin D from dairy products or supplements. Their bodies also make vitamin D when sufficiently exposed to sunlight. It is necessary for normal bone development. Calcitriol -- the active form of vitamin D -- is used to treat disorders including rickets (a vitamin D deficiency) and to regulate parathyroid hormone, which affects calcium levels in the blood.
Calcitriol has "potent anti-tumor activities," write the researchers, who included Adebusola Alagbala of the Roswell Park Cancer Institute in Buffalo, N.Y. But the story isn't quite that simple.
Lab-Made Versions Calcitriol increases the level of calcium in the blood. However, it may raise the blood's calcium level too high, which could lead to other dangers such as abnormal heart rhythms, muscle weakness, and confusion. The effect of hypercalcemia (elevated calcium levels) from the calcitriol limits its ability to be used to fight cancer, write Alagbala and colleagues. So scientists have made versions of calcitriol that don't affect the blood's calcium levels as much.
Alagbala's team studied calcitriol and a lab-made version of calcitriol (called "QW") in mice. Their results were presented at Frontiers in Cancer Prevention Research, a meeting held by the American Association for Cancer Research. Thwarting Prostate Cancer in Mice The mice were genetically programmed to develop prostate cancer.
The mice got calcitriol, QW, or a fake drug three times weekly for 14 weeks. Calcitriol and QW both slowed the progression of prostate cancer in the mice, the researchers report. Then, calcitriol was given to mice for a longer time -- up to 30 weeks. Calcitriol "markedly reduced tumor burden over time," write the researchers.
However, some mice experienced toxic side effects from calcitriol. Those side effects aren't detailed in the report. A group of castrated mice was given calcitriol, QW, or the fake drug for 12 weeks. In those mice, vitamin D compounds didn't slow, prevent, or affect prostate cancer development. Castrated mice don't make sex hormones. That may mean that vitamin D compounds work against androgen-sensitive prostate cancers, write the researchers.
SOURCES: American Association for Cancer Research's Frontiers in Cancer Prevention Research meeting, Baltimore, Oct. 30-Nov. 2, 2005. News release, American Association for Cancer Research.
And:
Vitamin D persuades the renin-controlling gene to become less active, and the whole process slows down.5
The end result is less angiotensin II and lower blood pressure."
Simplified: Mg drops, Ca rises, TNF alpha goes up, Angiotensin II goes up.
To block angiotensin II (cholesterol production at the beginning - in the liver) = Mg or Benicar (with dangerous side effects).
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Marnie
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posted
And...besides above...go to www.pubmed.com and in the search window, type in this #:
14995071
Mg decreased in prostatitis. Mg and zinc are found in "remarkabley high" concentrations in this gland...normally. If low...problems...like inflammation. That's what "itis" at the end of words means.
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