This is topic Please - need help with Igenex Igg/Igm results! in forum Medical Questions at LymeNet Flash.


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Posted by cutie (Member # 8468) on :
 
I am so overwhelmed and confused. I just got home from the dr. with my results. She said I am not "CDC" positive but I do have it. For those of you who know a lot about these tests, please help!

Here are my results:

IGM

23-25 +
28 +
30 +
39 IND
41 IND
66 +

IGG

41 +
39 IND
58 +
 
Posted by 5dana8 (Member # 7935) on :
 
hi cutie

CDC testing " This testing was set up for surveiallance purposes only, and is NOT intended to be used in clinical diagnosis.

Being CDC neg, meaning meeting their 5 bands doesn't mean squate.

Lyme disease is diagnosised by patient symptoms & history.

Do you have a good LLD ? They know how to interprete a western blot.

You should also click on the newbie links, as there are alot of great links that describe this.

take care

JMPO looks positive to me.

[ 04. March 2006, 08:52 PM: Message edited by: 5dana8 ]
 
Posted by Gretchen P (Member # 8403) on :
 
I hope this helps. Pay close attention to the lyme specific bands meaning only lyme can show positive on those bands.

9 cross-reactive for Borrellia
12 specific for Bb
18 unknown
20 cross-reactive for Borrellia
21 unknown
22 specific for Bb, probably really the 23/25 band
23-25 outer surface protein C (OspC), specific for Bb
28 unknown
30 unknown; probably an outer surface protein; common in European and
one California strain
31 outer surface protein A (OspA), specific for Bb
34 outer surface protein B (OspB); specific for Bb
35 specific for Bb
37 specific for Bb
38 cross-reactive for Bb
39 is a major protein of Bb flagellin; specific for Bb
41 flagellin protein of all spirochetes; this is usually the first to appear after a Bb infection and is specific for all Borrellia
45 cross-reactive for all Borellia (sometimes people with Lyme who have this band positive also have the co-infection Ehrlichiosis)
50 cross-reactive for all Borrellia
55 cross-reactive for all Borrellia
57 cross-reactive for all Borrellia
58 unknown but may be a heat-shock Bb protein
60 cross reactive for all Borrellia
66 cross-reactive for all Borrelia, common in all bacteria
83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane
93 unknown, probably the same protein in band 83, just migrates differently in some patients

Band 41 is often the first to show in a Lyme infection. IND means not positive and not negative, but in my opinion if it is not negative then it is positive. Band 39 is specific for Lyme. Remember that no Lyme test is completely reliable and results can vary by lab. Tests should be used to aid in diagnosis not determine diagnosis. Although the CDC requires a large number of bands to show for the test to be considered positive, many people who have Lyme do not have this many bands show. Often, Lyme doctors focus on which bands show, some are specific for Lyme disease.
 


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