Can someone help with test results interpretation? This is for my husband. (I have chronic lyme.) The Dr. office sent the results to us, but he hasn't had the opportunity to discuss the Igenex results with her by phone yet.
He had trauma induced CFIDS/FM 2 years ago, and has been in a more rapid decline the last 6 months.
30: Possibly a variant of outer surface protein A.
39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.
41: Flagella or tail. This is how Borrelia burgdorferi moves around, by moving the flagella. Many bacteria have flagella. This is the most common borreliosis antibody.
58: Heat shock protein.
66: Heat shock protein. This is the second most common borrelia antibody.
83: This is the DNA or genetic material of Borrelia burgdorferi. It is the same thing as the 93, based upon the medical literature. But laboratories vary in assigning significance to the 83 versus the 93.
93: The DNA or genetic material of Borrelia burgdorferi. In my clinical experience, if a patient has symptoms suspicious for borreliosis, and has one or more of the following bands, there is a very high probability the patient has borreliosis.
These bands are 18, 22, 23-25, 28, 30, 31, 34, 37, 39, 41, 83, and 93. This is true regardless of whether it is IgG or IgM.. But again, there is no universal agreement on the significance of these bands."
Concerning the "IND" ... It used to be called "equivocal".. This is what Dr C says about the IND:
"Controversy exists about band intensity. Many would say the " +/-" equivocal bands are not significant. The problem I have with that, is that there are "-" negative bands. The lab has no trouble calling some bands negative. So they must be seeing something when they put "+/-" at some bands.
The only thing that makes sense, is that there is a little bit of that antibody present in your serum. If the "+/-" equivocal is reported on the borrelia associated bands, it is usually significant, in my clinical experience."
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So, in other words, the IND is a weak positive. That means that bands 39 and the 83-93 are VERY SIGNIFICANT in your husband's testing results!
Posted by hopeful4 (Member # 8486) on :
Thank you Rob and Lymetoo for your help on this. It takes awhile for it all to filter into my brain. Thanks so much.