I'm hoping someone can help me to figure out a way to slow absorption of amoxicillin... ( or get it across into my blood at higher level)
my current state is-
-wanting to get pregnant and going to fertility clinic in a couple of weeks ( CD57 has doubled in last year- feeling mostly symptom free!)
-amoxicillin is not high enough in my blood peak and trough levels (according to Dr B recommendations for pregnancy levels)
-don't want to take Protonix as there has been no testing of it through pregnancy
-currently taking 3 500mg pills of amoxi every 6 hours ( could take less every 3 hours but will get no sleep)
Any creative ideas? Thanks for your help!
Best- Sarah
Posted by LYMESCIENCE (Member # 9259) on :
Sarah, crush your antibiotics with a pill crusher so that they become a powder. Next, find a way to take them so that you can avoid the taste.
Examples: put the powder into a gellcap, mix with applesauce, ect....
Also, take your antibiotics only 2 x per day, but make each dose at least 875mg of crushed amox.
Then, get your levels checked. If the levels go up, by how much? If they go down, by how much?
Either way, we have learned cause and effect. That information will give you an abiltiy to make an intelligent choice if this fails. Make sure your blood levels are measured at baseline, ie: current strategy, and then after experiemtnal change has been exerted. With this information, you and your doctor can find a way to protect you and your baby, with the best possible decision.
Posted by sarahinnewyork (Member # 7179) on :
Thank-you LymeScience!
I'm going to also try taking them at a different lab tomorrow in case they are doing something wrong-
Seems so low in my blood for the dose I'm taking...
Well- we are all different- so perhaps I have an iron stomach!
Thanks for your help- Best- Sarah
Posted by sarahinnewyork (Member # 7179) on :
Interesting...although I take my magnesium away from antibiotics...
I take Mag-Tab SR which is a 12 hour slow release!!
Perhaps this has been my problem!!
Will test again-
Posted by Foggy (Member # 1584) on :
I took Amoxy with Probenicid to keep it in my sys longer. There's a blood test to measure the results.
Posted by LYMESCIENCE (Member # 9259) on :
Foggy is correct. Probenicid does raise your levels.
The advice I gave you regarding the crushing. Just trust me on that one, I've tested it several times, it works to increase the absorbtion. The reason we aren't absorbing the meds has something to do with gut motility. For whatever reason, by crushing them into a powder, you are able to allow your body to kinda but not fully, curcumvent this process.
Many people, if not most, with Lyme Disease have nerve communicational problems with the Vegas Nerve.
This nerve travels down from the brainstem all the way to the gastrointestinal tract.
Any lymies remember having weird bowel sounds??
Anyone ever seen their abdominal muslces or intestines kinda... move as if they were rearranging themselves?
This is Bells Palsy of the Gut, and is probally quite common in Chronic Lyme Disease.
An article on this topic can be found at www.ilads.org Posted by LYMESCIENCE (Member # 9259) on :
As always, discuss anything you read here with your doctor.