NK cells are natural killer cells that every day destroy precancerous cells in us...about 4 a day.
"Antibody Dependent Killer (K) and Natural Killer (NK) cells (ASCC) kill by extracellular cytotoxicity by binding to a target cell and secreting cytolysins which unidirectionally kill the target cell.
Once the target is bound by an NKAR and no NKIR is activated, the cytotoxic reaction occurs. The interaction of cell adhesion molecules between NK and the target cell may tighten the attachment.
The first step is a MAGNESIUM DEPENDENT movement
of the cytoplasmix organelles (Golgi and granules) of the NK cell to face the target cell.
The secretion of the granule contents into the intercellular space is a
calcium dependent step
that results in the preferential insertion of perforin pores into the target cell membrane."
NK cell levels drop also when we exercise and are producing lactic ACID. We don't "need" them then...already acidic.
Too acidic is not good either...damages healthy cells.
NK cells only "work" if the environment is alkaline..as we are supposed to be...most of the time (nobody exercises constantly).
Posted by von (Member # 8333) on :