Hi everyone. I have a myspace page that I have dedicated to Lyme awareness. I have several blogs on there. But I would like to post one on why alcohol is so bad for Lymees. All my friends try to pressure me with just have one drink...
Its like were back in high school again. But anyways, I just want to post something about this subject where non-lymees as well as lymees can see it.
So I was just wondering if anyne knew of a good link to any article or story on why we cant drink. I keep trying to search but nothing comes up even though I know Ive seen these posts on here before and I know I started one once about alcohol making me really sick.
Posted by Marnie (Member # 773) on :
"Spirochetes have a limited metabolism and can only ferment a few types of organic molecules.
They ferment carbohydrates to acetate, ethanol , CO2, and H2 as major end products.
All spirochetes so far examined use the Embden-Meyerhoff-Parnas pathway to take glucose to pyruvate.
Under anaerobic conditions this is converted to acetate and ethanol using common fermentative pathways.
Interestingly, the facultative anaerobes in the group use both oxidative phosphorylation and substrate level phosphorylation in the presence of air and seem to be dependent on at least some fermentation.
The TCA cycle has not been detected in these microbes, and it is unclear how they get their ATP by oxidative phosphorylation.
B. burgdorferi will also move away from ethanol and butanol.
Alcohol, neurotransmitter systems, and behavior. From: The Journal of General Psychology Date: 10/1/2006
Alcohol affects several neurotransmitter systems within the brain. In this article, the author describes its effects on 5 major ones: glutamate, gamma-amino-butyric acid (GABA), dopamine, serotonin, and opioid systems.
(NK are natural killer cells...our first line of defense against precancerous cells.)
Clin Diagn Lab Immunol. 2002 Mar;9(2):282-6.
Impaired bactericidal activity and host resistance to Listeria monocytogenes and Borrelia burgdorferi in rats administered an acute oral regimen of ethanol.
PMID: 11874864
Vasdev S, Mian T, Longerich L, Prabhakaran V, Parai S.
N-acetyl cysteine attenuates ethanol induced hypertension in rats. Artery 1995;21(6):312-6
"All known pathways of ethanol metabolism result in the production of acetaldehyde, a highly reactive compound.
N-acetyl cysteine, an analogue of the dietary amino acid cysteine, binds acetaldehyde, thus preventing its damaging effect on physiological proteins.
(Above...unfortunately Bb has "zinc fingers" composed of:cysteine and histidine bound by zinc)
We have a "limited" amt. of the 2 enzymes needed to breakdown alcohol - alcohol deyhdrogenase is the first one. Women have less of this enzyme than do men.
Since the spirochetes are ALREADY fermenting sugar to ethanol/alcohol...adding a drink or two or more...may make things WORSE...significantly.
I have many more ethanol/alcohol files if you need them.
Pay close attention to HOW Flagyl works.
Flagyl + "extra" alcohol = alcohol poisoning (very life threatening).
Hope the above helps.
Posted by LisaS (Member # 10581) on :
Marnie, do you mind if I post this on my site?
Posted by Yashin (Member # 11159) on :
Lisa, can you please post your site link here so we can all see it? thanks
The first is my main page, the second is the link to go straight to the blogs. You can add your story or comments on these. Im also trying to start a slideshow called The Faces Of Lyme. I want people to realize just because we don't look sick, doesnt mean that we're not!
So if youre not shy, send me your pic and Ill post it. I wont use your name unless you want me to. I have a couple pics already but want a couple more before I put up the new slideshow. But I have another lide show of pictures of ticks and rashes and what not. Thanks! Oh and Id like to be able to put where the person is from or where they contracted theyre Lyme at I should say.
Also if you look at my friends list you will see other people with lyme sites also. Its interesting to read everyones stories.
Posted by lymeHerx001 (Member # 6215) on :
Caused me a major relaspse that im still trying to recover from 6 years later. Thats why.
I was an alcoholic for 6 months. Led to the worst 6 years of my life after.
Cant touch a drink now, not becuase of will power, simply because I get a hangover from a sip.
Yes a sip. Thats how fd up it is.
Posted by LisaS (Member # 10581) on :
I hear ya. I work at a bar on weekends. I dj. Well I used to love to have a couple captain and cokes. But I noticed my hangovers were way worse than my friends. Then I started not being able to move for a day or two after drinking.
So I quit for a couple years and then tried again. (This was all pre lyme diagnosis) But I was so sick the next day I ended up in urgent care. So I just thought I was allergic to alcohol or something. It sucks cuz its just about the only thing that relaxes me.
Posted by papersquare (Member # 11497) on :
Hi there, I know this is weird, but with me a little alcohol relieves symptoms and I am not sure why. Maybe because I sleep deeper and then that helps. All the chemistry info seems juicy but is too tough for my lymebrain. Is there noone around who shares my experience? Pet
![[dizzy]](graemlins/dizzy.gif)