LymeNet Flash: does rocephin cross the BBB

This is topic does rocephin cross the BBB in forum Medical Questions at LymeNet Flash.

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Posted by citruslyme (Member # 7851) on :

I read somewhere that rocephin crosses the blood brain barrier but now I cant seem to find the info.
does it actually get into the brain and spinal fluid
how bout ceftin
thanks

Posted by citruslyme (Member # 7851) on :

up

Posted by Michelle M (Member # 7200) on :

Rocephin = yes. Don't know about Ceftin.

Michelle

_________________________

Review of treatment options for lyme borreliosis.
Taylor RS, Simpson IN.

Micron Research Ltd, Ely, UK. [email protected]

Lyme borreliosis (Lyme disease) is the most common tick-borne bacterial infection and the incidence is increasing in parts of Europe and the USA. Prompt antimicrobial therapy using oral agents such as doxycycline or amoxicillin is successful among more than 90% of patients. Inadequate penetration of oral agents into the CNS may result in the development of overt neuroborreliosis. The parenteral agent ceftriaxone is the drug of choice for severe acute and chronic infections, due to good penetration into CSF, convenient single daily dosage regimen and proven high efficacy in clinical trials involving a wide variety of disseminated infections. Regardless of therapeutic agent, there appears to a small minority of patients (<10%) who do not respond; such cases may be due to long-term persistence of borrelial cysts and to misdiagnoses based solely on seropositivity. Several adjunct therapies are available, including hyperbaric oxygen therapy and immune system supplements, but clinical trials have yet to be conducted.

PMID: 16315580 [PubMed - indexed for MEDLINE]

Posted by citruslyme (Member # 7851) on :

Thanks Michelle for the valuable info!!! [group hug]

Posted by hostbody (Member # 12695) on :

Cleared up my brain fog and memory problems after the first month!

I took it for 7 months.

My advice would be to stay on it at least a month after your symptoms have completely resolved. No herx.

I had mine removed too early because I was parinoid about pic-line infection.

Many people in my Support Group have gone into complete remission with IV rocephin. Hope you do too!

Posted by citruslyme (Member # 7851) on :

thanks that sounds very hopeful