The following are my results. IGG-Result Negative All bands negative except the following. **31 kDa Indeterminate **41 kDa Indeterminate IGM-Result Negative All bands negative except the following. **39 kDa Indeterminate **41 kDa Indeterminate
I will call Doctor C's ofice in MO this week to discuss, but I would like some feedback from you folks.
What does this mean if anything? I guess I still do not have a definite answer.
My initial thoughts are that I am still having muscle twitching and jerking issues, a left ear that rings 24 hours a day and eye floaters pretty much daily so why not try the ABX?
Thanks for any responses given. Roger
Posted by chamade (Member # 11472) on :
I checked your symptoms in your previous post and they are pretty much identical to what mine were (burning, eye pains, shooting pains down arms, twitching etc.).
My IGM was 39+ and 41 IND. Now that I re-tested after 2 months on abx: 39+, 58+, 23-25 IND. Just based on symptoms and negative MRI findings I would definitely go to an LLMD and try antibiotics.
Posted by Lymetoo (Member # 743) on :
Missouri: You have a problem!!
Band 39 is VERY Lyme-specific. Read Dr C's explanation on the Western Blot, including all of the responses to the post:
If you are treated with abx and then retested, that band 39 will likely show positive.
From the above link:
"If enough of the complexes are formed, eventually it may be seen with the naked eye as a dark band. - Band intensity reflects how dark or wide it is. Controversy exists about band intensity.
Many would say the " +/-" equivocal ["IND"] bands are not significant. The problem I have with that, is that there are "-" negative bands. The lab has no trouble calling some bands negative. So they must be seeing something when they put "+/-" at some bands.
The only thing that makes sense, is that there is a little bit of that antibody present in your serum. If the "+/-" equivocal is reported on the borrelia associated bands, it is usually significant, in my clinical experience. This is a strong clue that I am on the right track." {Dr C}
"39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.
The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93." {Dr C}
Posted by bandit100 (Member # 11941) on :
Thanks for the responses!
Posted by pamn (Member # 12405) on :
Hey, I thought Igenex is such a great lab & they come up with a 39 & call it indeterminate? I don't get it. Do I really want to spend all that money to get myself tested there?
Pam
Posted by Lymetoo (Member # 743) on :
No, it's indeterminate because it was weakly positive. The band did not show up "dark" as it would if it were clearly a positive.
"If enough of the complexes are formed, eventually it may be seen with the naked eye as a dark band. - Band intensity reflects how dark or wide it is. Controversy exists about band intensity.
Many would say the " +/-" equivocal ["IND"] bands are not significant. The problem I have with that, is that there are "-" negative bands. The lab has no trouble calling some bands negative. So they must be seeing something when they put "+/-" at some bands.
The only thing that makes sense, is that there is a little bit of that antibody present in your serum. If the "+/-" equivocal is reported on the borrelia associated bands, it is usually significant, in my clinical experience. This is a strong clue that I am on the right track."