I came across this just now and thought it was helpful. And in the "common uses" section it actually mentions Lyme Disease on a few of the antibiotics.
"Modern research on antibiotic therapy began in Germany with the development of the narrow-spectrum antibiotic Salvarsan by Paul Ehrlich in 1909, for the first time allowing an efficient treatment of the then-widespread problem of Syphilis. The drug, which was also effective against other spirochaetal infections, is no longer in use in modern medicine."