I've heard that many sufferers of Lyme disease undergoing treatment have their symptoms flare up on a regular cycle...I'm just interested to hear people's experiences as to how often their flareups occur,the duration, and what symptoms are exacerbated? For my part, my symptoms seem to spike every 6 weeks or so. I have an exacerbation of anxiety, heart palpitations, muscle twitches, and dizziness. I only seem to get headaches during a flare, and I always break out in a hot/itchy rash in the same places.