I would think that an antibiotic with a longer half life compared to the others would be better in combating lyme. I figured this would be true because of Borrelia's slow growth, but then I notice some people have success with short half life antibiotics like Biaxin. I would think azithromycin or Minocycline would be better. Could someone please bring a little more to the table on this subject because I am very curious. Thank you.