anyone know what the deal is with lyme (and coinfections) infecting your tendons/connective tissues especially around the bigger joints? i know they run away from abx to areas of little blood flow... but i have a hard time telling if i am actually just feeling pains of bugs dying in the joints (due to increase in exercise/attempt to recondition- guided by a phys therapist) or if i am actually straining (or worse), these tendons and ligaments. it also seems that the rice crispy crunchies that happen in the tissues around the joints often cause soreness afterwards. microstrains?
anyone know?
btw, no quinolones for me, so that is not the cause here.
Posted by Tincup (Member # 5829) on :
Hey hey...
Here is an abstract that might help.
Happy New Year!
Persistence of Borrelia burgdorferi in ligamentous tissue from a patient with chronic Lyme borreliosis.
Haupl T, Hahn G, Rittig M, Krause A, Schoerner C, Schonherr U, Kalden JR, Burmester GR.
Department of Medicine III, University of Erlangen-Nuremberg, Germany.
OBJECTIVE. To document the persistence of Borrelia burgdorferi in ligamentous tissue samples obtained from a woman with chronic Lyme borreliosis.
METHODS. Spirochetes were isolated from samples of ligamentous tissue, and the spirochetes were characterized antigenetically and by molecular biology techniques.
The ligamentous tissue was examined by electron microscopy. Humoral and cellular immune responses were analyzed.
RESULTS. Choroiditis was the first recognized manifestation of Lyme disease in this patient.
Despite antibiotic therapy, there was progression to a chronic stage, with multisystem manifestations.
The initially significant immune system activation was followed by a loss of the specific humoral immune response and a decrease in the cellular immune response to B burgdorferi over the course of the disease.
"Trigger finger" developed, and a portion of the flexor retinaculum obtained at surgery was cultured. Viable spirochetes were identified.
Ultramorphologically, the spirochetes were situated between collagen fibers and along fibroblasts, some of which were deeply invaginated by these organisms.
The cultured bacteria were identified as B burgdorferi by reactions with specific immune sera and monoclonal antibodies, and by polymerase chain reaction amplification and Southern blot hybridization techniques.
CONCLUSION. To our knowledge, this is the first report of the isolation of B burgdorferi from ligamentous tissue. This suggests that tendon tissues serve as a specific site of spirochete residence in human hosts.
PMID: 8240439 [PubMed - indexed for MEDLINE]
Posted by dg0207 (Member # 15623) on :
Hey John,
I am in the same dilema.
A lot of connective tissue pain, especially around the knees.
I treated Lyme aggresively w/ IV. Trying to rebuild body, not sure if I am still infected or am doing damage from too much exertion.
Sometimes I think I have a connective tissue disorder though lab results not high enough too state it.
My nutrition is good but sleep is hard at times.
Keep posting on this.
Posted by dmbfan (Member # 11948) on :
my latest symptoms are problems with shoulder joints, and elbows, and knees. Feels like tendon or ligament or something like that. My llmd says its classic lyme. My chiriopractor is fascinated by me...
![[Big Grin]](biggrin.gif)