This is topic 58 BAND??? NEED HELP UNDERSTANDING THIS. in forum Medical Questions at LymeNet Flash.


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Posted by poohbear74 (Member # 18766) on :
 
CAN SOME ONE TELL ME WHAT THIS ONE IS...

[ 02-03-2009, 02:26 PM: Message edited by: poohbear74 ]
 
Posted by Snailhead (Member # 18091) on :
 
The definition I have is "heat shock protein". I have this one too.
 
Posted by TerryK (Member # 8552) on :
 
Band 58 was added as a borrelia specific band in Scotland in order to make diagnosis of lyme disease more accurate.

http://jmm.sgmjournals.org/cgi/reprint/54/12/1139.pdf

I don't know what that means for US strains but in "Cure Unknown" it is mentioned that the US strain and European strain are genetically the same.

Aside from that, I've read it may be a heat shock protein too.

You may be able to find out more by digging around in pubmed or google.

Terry
 
Posted by poohbear74 (Member # 18766) on :
 
MY TEST IN OCT WAS ABNORMAL FOR 58 FROM LAB CORP
NOTHING ELSE

THEN IN JAN 41KD WAS + BUT NO 58 FROM QUEST

THAT JUST SHOWS HOW CRAZY THE TEST RESULTS CAN BE...
 
Posted by TerryK (Member # 8552) on :
 
You can get different results at different times because the outer surface proteins change so that borrelia can evade the immune system.

Also, I've read that even temperature can change results.

Lyme is a clinical diagnosis. There are no accurate tests. Perhaps an antibiotic challange would help? You can look on IgeneX website or call them to get the details.

The best way to find out if you have lyme is through an ILADS lyme doctor. They will know how to do an appropriate physical exam and history along with interpretation of tests and possibly results of an antibiotic challenge.

Go to the bottom of the page here and click to find a doctor.
www.ilads.org


Terry
 
Posted by Keebler (Member # 12673) on :
 
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I don't think it is so much something called "heat shock protein" but that is the way they do many of the tests.

If a particular protein can be identified that links to a certain microbe.

It's more complex but my understanding of it stops there. Sorry.

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PoohBear,

are you seeing a LLMD? If so, they should be able to explain this.


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TESTING

You should also be evaluated for coinfections. Not all tests are great in that regard, either, but a good LLMD can evaluate you and then guide you in testing. One of the top labs is:

www.igenex.com

IGENEX

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There are a couple other good labs for certain tests: Fry; Clognen; Focus. Your LLMD will know.


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Dr C's Western Blot explanation:

http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=042077


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Posted by Keebler (Member # 12673) on :
 
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You will find more here, too:


http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=029917


treepatrol's - Topic: Newbie Learning Help Links 5/21/08


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http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=069262


Topic: BettyG's NEWBIE PACKAGE, 7.19.08, with TABLE OF CONTENTS FOR ALL!


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Posted by Lymetoo (Member # 743) on :
 
Be sure to read Dr C's western blot explanation.
 


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