This is topic Is Chronic Fatigue Syndrome caused by a Circovirus brain infection? in forum Medical Questions at LymeNet Flash.


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Posted by emla999/Lyme (Member # 12606) on :
 
Is Chronic Fatigue Syndrome caused by a Circovirus brain infection?

The pubmed citation:

http://tinyurl.com/dhk6qs


The actual article:

http://tinyurl.com/dzfzex


http://tinyurl.com/dgypz5
 
Posted by adamm (Member # 11910) on :
 
So what's a good lab to have test for this, and what do we do to treat it?
 
Posted by Blackstone (Member # 9453) on :
 
Well, its a nice hypothesis but as we all known CFS can be a symptom of many things - until the community as a whole stops treating it AS a condition rather than SYMPTOMS of a condition, it may be difficult to get good data. There is very likely no single cause for CFS, viral, bacterial, or other.

In theory, viral titers could be drawn for many of these infections, and antiviral drugs that are tuned to attack certain variants (ie. *cyclovir family for Herpetic strains) could be utilized.
 
Posted by emla999/Lyme (Member # 12606) on :
 
Adamm,

I don't know where a person could go to get tested for circoviruses and polyomaviruses. And I am not sure if there is a drug that is effective for those viruses. Maybe, Valcyte or Valtrex could be helpful.??? I don't know.

However, the author did say that other viruses such as HHV-6, EBV, Enteroviruses, CMV could also breach the blood-brain barrier and cause CFS. And fortunately, testing and treatment is readily available for those viruses.

What I found to interesting about this article was that the author stated, "these common viruses can breach the blood-brain barrier, infect the brain and cause CFS.

The blood-brain barrier usually protects the brain from infection, but sometimes this barrier can be weakened and viruses not normally present in the CNS can gain entry."


What's causing the blood-brain barrier to become so weakened that it's allowing these viruses that are not normally present in the brain to now gain entry into our brain?

Could the cause of this weakened blood-brain barrier be Lyme Disease or is it something else?

Would having Lyme Disease cause the blood brain barrier to weaken and thus allow these viruses to enter into our brains and cause neurological symptoms?

And even if we could completely irradicate Lyme Disease/borrelia from our body would that cause the viruses to be killed off and thus leave our brain virus free?

Or, regardless of whether we completely irradicate Lyme Disease/borrelia from our body or not would these viruses still be present inside of the brain where they could still be causing all sorts of neurological symptoms?
 


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