This is topic Can a glutathione IV push that is too fast cause health problems? in forum Medical Questions at LymeNet Flash.


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Posted by Janice70 (Member # 16319) on :
 
The nurse at the LLMD pushed it too fast today and my husband passed out. The doctor said it wouldn't

cause any health problems but I'm worried.

Anyone who has been following this, don't worry--We will NOT get this done by the nurse again.

I'm looking for some other place to get it done.
 
Posted by feelfit (Member # 12770) on :
 
yikes! I did not tolerate it well. Most people do.

My BP would skyrocket, I would become lightheaded and my arms, shoulders and chest, would become red.

at first we thought that it was because of the pre-loaded syringes, but we tried it with fresh from the vial and I still reacted.

I felt ok after about 1/2 hour, but in the end I gave up on them because my reaction was not normal.

Maybe your husband has a sensitivity?

Should be pushed over at least 5 minutes.

Feelfit
 
Posted by Janice70 (Member # 16319) on :
 
The first time he got the IV glutathione, he had no noticeable problems, even though the nurse

tried to push it with the band still around his arm.
 
Posted by feelfit (Member # 12770) on :
 
OMG! How faast did the nurse push it today? My first push I had no reaction either.

FF
 
Posted by Janice70 (Member # 16319) on :
 
It was supposed to be 10 mL of 200 mg/mL, but from the looks of what's remaining in the bottle, it could have been more.

My husband said it took about 2 minutes.
 
Posted by Lonestartick (Member # 2151) on :
 
You might wish to inform your LLMD's office and the nurse that your husband may have suffered an episode of "Speed Shock" as a result of a medication being administered too quickly.

Speed shock is not the same thing as an allergic reaction. Speed shock occurs when a foreign substance is rapidly introduced into the circulation, permitting it to concentrate in the plasma in toxic proportions. Then it may reach heavily perfused organs in toxic proportions causing syncope, shock and even cardiac arrest.

Fortunately Speed Shock can be avoided by using precautionary measures, which include never administering a medication any faster than it is supposed to be infused.

If your nurse is unfamiliar with the concept of speed shock in intravenous therapy, you might wish to avoid her and that office altogether. It is nothing to fool around with, especially since it is easy to avoid.
 
Posted by feelfit (Member # 12770) on :
 
That nurse is not familiar with procedure...obviously! Two mis-haps now. I would not go near them again. Hope your husband is ok now.
 
Posted by Janice70 (Member # 16319) on :
 
We WILL NOT be using that nurse again.

I really, really hope we can find some other place that can give him the infusions, with the doctor's prescription.

I am so worried that this might have caused permanent harm. Does anyone know if that is a possibilty? He seems to be okay now.

The LLMD is aware of the situation. He's the one who told my husband that it was pushed too quickly.
 
Posted by Lonestartick (Member # 2151) on :
 
I'm sure that was a very uncomfortable and frightening experience for your husband and you. I'm sorry you all had to go through something like that, but I really doubt there is anything to worry about long term as far as any adverse effects go.
 
Posted by Snailhead (Member # 18091) on :
 
When I do my IV ceftriaxone I even have to push the saline slow, it makes me lightheaded. I'm sorry your husband had a second issue. Hope you can find a better fit, and it's ok to tell (notice I say tell, not ask) your healthcare provider to "go slow". Better yet, maybe your husband can be the "pusher". (not that kind, but you know what I mean [Smile]
 
Posted by seibertneurolyme (Member # 6416) on :
 
Hubby used to have the opposite reaction. IV glutathione was one of the few things that would wake him up from one of his seizure-like spells so I could get him into bed. I gave him IV glutathione pushes almost daily for about 4 years. I usually only did 500 or 1000 mg although sometimes we did 2000 mg.

But prior to this his first IV glutathione drip was a nightmare. Actually the first one was ok. Got 400 mg I think. Went back the next day for 600 mg -- started shaking and trying to throw up. Scared the nurses and patients in the office.

I had to pull the car over every 20 or 30 minutes during the drive home so he could vomit(a normal 4 hour drive took about double that with the traffic stop due to an accident).

Hubby was not willing to try glutathione again for about a year after that experience. This was at the start of his illness when we thought it might still be a mercury problem and his tickborne illnesses were not diagnosed for another 2 years.

It might be a good idea to find out the source of the glutathione. In my opinion the best source is in Atlanta -- can't remember the names of the 2 major compounding pharmacies there. One is quite a bit cheaper but is still ok. Appothecure from Dallas does not seem to have the same quality product.

This is not medical advice, just my opinion based on hubby's experiences.

Bea Seibert
 
Posted by hcconn22 (Member # 5263) on :
 
I did mine tonight in about 1 minute because I was watching TV and not paying attention. No problems here.

Was instructed it should be done over 2-5 minutes, so 2 min is not that crazy. Again each person is different.

You can also pass out from the needle in the IV-- this is quite common, its called vasovagal.
 
Posted by luvs2ride (Member # 8090) on :
 
Too much glutathione can cause lightheadedness and dizziness.

Dr Schaller talks about it in his book "The diagnosis and treatment of Babesia"

Otherwise, he lists no negative side effects.

Glutathione has been my lifesaver and I will take it the rest of my life as genetically I test poorly in my ability to produce my own.

Most all chronically ill people are deficient in glutathione.

Definitely tell your doctor about your reaction.
 


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