HINT HINT!!!
Posted by seekhelp (Member # 15067) on :
Right over my head.... lol.
Posted by Marnie (Member # 773) on :
Bb has "zinc fingers"...when zinc is separated from proteins (minerals bind to acids and proteins are acidic) and zinc is then "floating around" in excess, it is extremely toxic.
This is zinc in excess:
In terms of zinc toxicity, there is no other way to put it: excess zinc is dangerous!
This is primarily true because too much zinc will likely interfere with the metabolism and absorption of other essential minerals in your body, most especially iron, magnesium and copper.
Zinc side effects can become potentially serious if you take doses from 150 to 450 mg a day. Taking this much can decrease your copper, iron and magnesium levels, reduce your body's immune function, and reduce your HDL (good cholesterol) level.
...result in gastrointestinal problems, anemia, poor immunity, dizziness, vomiting and other symptoms. An acute overdose of zinc can cause symptoms such as vomiting, stomach pain, diarrhea and fever.
This will blow you away:
January 2009 - Fixodent, Poligrip, Super Poligrip and other popular denture adhesive creams have recently been linked to serious neurological side effects.
Among these dangerous side effects is a nerve disorder called neuropathy, a condition in which a person suffers from peripheral nerve damage. Denture Cream Lawsuits are being filed now, as seen on Good Morning America.
Fixodent, Poligrip, and other popular denture adhesive creams have recently been linked to serious neurological side effects. Among these dangerous side effects is a nerve disorder called neuropathy, a condition in which a person suffers from peripheral nerve damage.
Neuropathy, also referred to as peripheral neuropathy, is typically characterized by pain and numbness in the hands and feet. While most commonly caused by diabetes, neuropathy can result from many other problems, including traumatic injuries, infections, metabolic problems and exposure to toxins. One such toxin is the mineral zinc.
Zinc in Denture CreamDenture adhesive creams, such as Fixodent and Poligrip contain zinc.
Although zinc is safe if ingested in small amounts, it can be dangerous, and even deadly, if taken in excess.
In addition to neuropathy, zinc overdose can lead to zinc poisoning, copper deficiency, and other neurological side effects.
In August 2008, a study published in the journal Neurology reported on four patients who suffered from neuropathy and other neurological side effects associated with zinc poisoning from denture cream.
The study, which was conducted by researchers at the University of Texas Southwestern Medical Center in Dallas, noted that while one tube of denture cream should last 3 to 10 weeks, patients in the report were all using at least two tubes of denture cream a week.
Trust me, seekhelp, you ARE suffering the effects of too much zinc.
Posted by Cass A (Member # 11134) on :
Dear Marnie,
Thanks for this data.
I have "Zinc Status," a product I got at my local health food store. If you put the liquid in your mouth and your zinc level is adequate you may get an immediate taste sensation--within 10 seconds or so.
Even when taking 200 mgs a day of zinc, neither my husband nor I can taste a thing when we do this test--even swishing it around for a minute or so.
Pfeiffer Clinic found that SOME people have a genetic predisposition to excrete too much zinc and B6. And, the percentage of people with this genetic situation doesn't reach 50% even in the people with serious mental disorders that they studied--it was, however, way, way more prevalent than in the general public.
The studies you cite are not ALSO screening for people with this genetic problem, are they?
So, their data on toxicity problems may NOT apply to people who are "genetically" compromised to not keep the zinc in the body that the body needs to function.
I know that zinc can actually turn off post partum psychosis--if ramped up. Also schizophrenia. Also severe leg cramps. And a few other things....
It seems prudent to do some testing to find out what a person's situation is regarding zinc, before going overboard either direction.
Best,
Cass A
Posted by Marnie (Member # 773) on :
Bb has "zinc fingers" which look to be zinc attached to cysteine and histidine.
Bb is depleting OUR zinc (as well as a ton of other nutrients!).
When Bb is destroyed, does our body then break up those "zinc fingers" -> excess zinc, excess cysteine and excess histidine (which converts to histamine!)?
I would think if one has a genetic problem with excreting too much zinc, that would be a "benefit" if infected with Bb.
I was hopeful about Disulfiram - until I learned that drug, while it DOES lower MMP2 and MMP9 (collagenase) - which would be HELPFUL - might not be the "cure".
Several drugs (e.g., metronidazole = flagyl) cause a similar reaction known as "disulfiram-like reaction."
If flagyl/tinidazole worked, my sister would have been cured (she had more than one "round").
I found this abstract that indicates why it might NOT work:
The effect of the alcohol-deterrent drug, disulfiram, on mitochondrial Ca2+ content was studied.
***Addition of this drug (20 �M) to mitochondria induces a complete loss of accumulated Ca2+.***
The calcium release is accompanied by a collapse of the transmembrane potential, mitochondrial swelling, and a diminution of the NAD(P)H/NAD(P) radio.
These effects of disulfiram depend on Ca2+ accumulation; thus,
ruthenium red reestablished the membrane (Greek symbols delta and psi)and prevents the oxidation of pyridine nucleotides.
The binding of disulfiram to the membrane sulfhydryls appeared to depend on the metabolic state of mitochondria, as well as on the mitochondrial configuration. In addition, it is shown that modification of 9 nmol -SH groups per mg protein suffices to induce the release of accumulated Ca2+.
Bb already has a dislike for Ca. In fact it has a gene to EXPORT Ca from the cells AND it has a PKC inhibitor P= protein K= kinase (transfer phosphate), C=calcium activated.
Bb is INHIBITING calcium from transferring a phosphate.
Photon therapy looks to activate a G-helper protein called transducin which CLOSES the TRPM8 channel (which in the animation looks to
"trap" Na and Ca IN the cells.
This would "counter" Bb's CALCIUM activated INHIBITOR and allow a phosphate transfer to happen.
I was also interested in the fact that:
***ruthenium red*** reestablished the membrane (Greek symbols delta and psi)and ***prevents the oxidation*** of pyridine nucleotides.
I have long suspected Bb's PKC inhibitor is the subset PKCd - delta. This is the first time I have run across the psi symbol and will have to try to figure out the link.
So instead of trying to "oxidize" Bb's outer cell wall proteins (which it can rebuild), the oxygen in the cell could be used by the mitochondria instead to make MORE ATP.
Bb is camped out in the cytoplasm of the cell where it is using glucose to make ATP.
Our mitochondria need glucose AND oxygen to make a LOT of ATP which will drive Mg back in - to attach to ATP as Mg-ATP to transfer phosphate groups and get the infected cells working once again. Those infected cells are suffering with "mitochondrial dysfunction". Their powerhouses are kapoot.
They can't do their jobs if they are "hungry" for oxygen and glucose...and Mg.
Now IF caught really fast, Doxy binds Ca and since our own immune cells need Mg (which dives at the outset) and Ca to be made, we can't make immune cells if we don't have enough Mg AND Ca.
Bb INFECTS our own defense cells.
If we don't MAKE defense cells for the lack of nutrients, Bb has nothing to infect, yes?
But once Bb has a foothold, the ball-game changes.
I will look once again at my bladder cancer post to try to make the connections.
That "soup" of nutrient supplements (which also lowers MMP2 and MMP9) is interesting...green tea, lysine, alanine, etc.
Genetics sure plays a part! I'm dealing with a very sick daughter now who I think may have the B16 arg/arg gene (too much arginine out of balance with lysine) and she was given the BC pill, Yasmin, which was disastrous for HER.
She NEEDS higher levels of aldosterone and lower levels of potassium because a potassium DEFICIENCY
CONSERVES LYSINE. Thus the arginine and lysine remain balanced.
It is amazing how the body will adapt to a gene "mistake".
There is a component in Yasmin that does the opposite of the above (lowers aldosterone and raises potassium) which was very very harmful to her.
She now has nearly every lysine deficiency symptom and more.
She is asthmatic and according to many websites, doctors are supposed to take that into consideration as a possible conflict.
My daughter on occasion uses a Ventolin inhaler when she has an asthma attack.
Ventolin is a beta 2 adrenergic agonist (helper) that increases the sodium/potassium/ATPase pump which moves extracellular K+ INTO the cells and
LOWERS SERUM POTASSIUM.
Yasmin can indeed cause hyperkalemia and not only lowers aldosterone, but one of the androgens (and more) too.
What a mess!
[ 05-25-2009, 06:05 AM: Message edited by: Marnie ]
Posted by Carol in PA (Member # 5338) on :
Marnie,
Kudzu is used to reduce alcohol cravings.
It also helps stop cluster headaches, and may help migraine.