my llmd want to do me some clindamycin (2100mg/day) + 500mg quinine/day.
she would like to have some articles about babesia treatment, especially about the clinda/quinine combination. other combinations are fine too... like atovaquon and azi... i already searched but i found no articles written by some DRs or LLMDs.
greetz
Posted by Sammi (Member # 110) on :
daniel, are you sure the dose of Clindamycin is correct? I believe the typical dose is 600 mg daily.
Has your doctor seen Dr. B's treatment guidelines at http://www.ilads.org/lyme_disease/B_guidelines_12_17_08.pdf He discusses Babesiosis starting on page 22 and treatment for it starting on page 23. He states that this combo can have serious side effects.
Posted by sparkle7 (Member # 10397) on :
Why is your doctor asking you to do research for her?
Posted by seekhelp (Member # 15067) on :
My former LLMD did very weak doses of Clindamycin/Quinine, BUT that doesn't mean it's easy to handle! They were 600 mg Clindamycin/300 mg Quinine. Quinine is ruthless on your ears and Clindamycin, while I believe very effective, is a big risk for C-Diff.
Daniel, your doses are what the IDSA recommends (yeah you read that right). However, they believe it's cured easily in a few days. Neither seems to be accurate. My old LLMD pulsed 10-day cycles twice. The concensus here is a minimum of 4-6 months is needed and different strains of Babesia respond to different meds (if at all). Curing it in 3 days or 20 days is a pipe dream.
the bottom line is the research done to date on Babesia is a joke! I looked up everything possible on WA-1 and came up with NOTHING. It's not fair or right. I believe the IDSA is covering this illness up.
Posted by daniel (Member # 22201) on :
hey,
i've already printed the burrascano guidelines.... like i said, she would like to have some feedback about the clinda/quinine therapy too.
i know i take a high dose, thats are 900mg i.V. and 2x 600mg oral clindamycin a day.... + the quinine i have to take the 900mg i.V. firstly for 2 weeks... and how i respond to it she will give me another 2-4 weeks. this protocol is famous here and already done a few times by an another llmd. i have to do some research for my llmd because im a different case... not many sick people here have babesia... or bartonella, i have both. (live in germany).
greetz
Posted by Sammi (Member # 110) on :
Hi daniel. Initially you posted the Clindamycin dose was 2100 mg. I believe 1200 mg is still higher than typically prescribed here, but it is not as high as 2100 mg.
Just be cautious with the side effects of Quinine.
Good luck!
Posted by luvs2ride (Member # 8090) on :
Why don't you do Mepron/Zithromax? That has been found to be better tolerated and more effective.
Posted by seekhelp (Member # 15067) on :
Probably too expensive Luvs.
Posted by sparkle7 (Member # 10397) on :
There are a couple of books about babesia but I'm not allowed to mention the doctor's name here.
PM me if you want further info.
You could also do a search on Amazon.com for - artemesia, babesia, medical treatment - to find them.
Posted by daniel (Member # 22201) on :
because mepron/zithromax is more expensive as clindamycin and quinine.. i will try clindamycin and quinine first and if i tolerate it well.. i will go on for 6-8 weeks.. than i want to switch to mepron/azi for another 8 weeks
what about lariam???
greetz
Posted by Amanda (Member # 14107) on :
Probably the best source for medical literature is www.pubmed.com
It is based in the U.S. but there are medical articles from all over the world. Type in key words, and it will search them for you.
I took Mepron and zith for 26 months. For the first year and a half, it seemed to help some, but then I slowly got worse. I am having much better sucess with Larium.
One thing you will find is that many of the lyme doctors use drugs "off label". Meaning that the lyme literate MDs are experimenting with drugs and dosages NOT found in any literature because we know so little about tick diseases. Also, what works for one person sometimes doesn't work for another.
I would encourage your MD to contact the International Lyme and Associated Diseases Society (www.ILADS.org). Its a medical organization. Your doctor can go there and look for guidelines, and also contact other ILADS MDs.
So, I agree, try the stuff that is least expensive first. There have been a few people here who said they got the best results from using clindamyacin.
The person on this site that has tried everything and knows alot about being a patient trying to rid himself of Babesea is Groovy2. You can private message him. I believe he is having great success with a short course of clindamyacin, then stopping that and taking primaquine.
Posted by daniel (Member # 22201) on :
thanks a lot Posted by daniel (Member # 22201) on :
im takin clinda and quinine now since tuesday.. today im feeling very weak.. i have no power and my body is hurting here and there... a little bit dizzy too.... on thursday i had some stomach issues but they are gone... hope the weak_/fatigue feeling will improve soon.. Posted by valeriedc (Member # 24950) on :
Larium is one drug I'm taking. After the loading dose, which caused me dizziness, reduced appetite and generally feeling off (Day 1 was tough, Day 2 better then fine), I haven't really noticed any symptoms. Definitely feeling better with reduced symptoms. Mepron and Malarone didn't seem to have much or any impact.
The wisdom on this site and from my llmd is that everyone is different and trying different med combos is generally the case for many sufferers.
![[Smile]](smile.gif)
However, they believe it's cured easily in a few days. Neither seems to be accurate. My old LLMD pulsed 10-day cycles twice. The concensus here is a minimum of 4-6 months is needed and different strains of Babesia respond to different meds (if at all). Curing it in 3 days or 20 days is a pipe dream.