My llmd told me tinidazol is the most important antibiotic against lyme, but I cant stand the side effects any more.
i get strong brainfog, am very confused, cant concentrate at all, feel like im drunk and not being me anymore - though i only take a small dose (250-500mg/day) and only did so for a few days.
im not even sure its sideeffects. it could also be lymesymptoms triggered by tinidazol.
because of a bad flagyl-experience i fear that these symptoms will stay. i had problems with flagyl years ago. when i first took it i had no problem. but then i was on highdose-IV-flagyl (1000mg IV plus 1000 oral) i suddenly started feeling extremely brainfoggy. i didnt go away. the feeling of being drunk even lasted for months after i stopped flagyl and came back later. my llmd was suprised about that and didnt have an explanation.
now similar symptoms appear while on tinidazol. i only can move very slowly at the moment which is frightening. everybody says this med so important, but i dont wanna risk too much for it. what do you think?
im also on mino (100mg/day) and plaquenil (1 tbl/day) and have taken them weeks before tini without problems.
[ 07-18-2010, 08:47 AM: Message edited by: steven ]
Posted by TerryK (Member # 8552) on :
I could only take tini for a few weeks because I got a black tongue which is listed as a side effect and is caused by fungus.
Fungus can be really hard for anyone to handle because it can bring down the immune system but also because it creates mycotoxins which can be very difficult for some of us to get rid of.
Are you on a good anti-candida/anti-fungal protocol? Are you taking plenty of good quality probiotics? Are you on a good detox protocol? You may want to add those if they aren't part of your program already and you might want to consider taking a mycotoxin binder while on tini in case that is part of the issue.
Those are the things that I think might help you stay on it.
Hopefully someone else has more ideas.
Good luck.
Terry I'm not a doctor
Posted by stephfino (Member # 23599) on :
Im finishing up my first week of Tindamax. What a week it's been!! Horrible headaches-ANXIETY-twitching-just really it has stirred up all my symptoms.
I refuse to stop it now-It must be working, as I was feeling 90% better before throwing this into my regime. Im assumming Im herxing...
Even though I feel horrid now-I just want to get rid of this ASAP and get on with my life. I hope those little f***ers are dying a miserable death ;0)
Posted by nefferdun (Member # 20157) on :
I am pulsing it twice a week and have had no problems. I take nystatin every other day and do not have yeast either. A couple of times after taking it I have had intense pain where the bart is in my legs so I think it is also helping with that. I have never had pain in the soles of my feet with bart, just my shins, but I have woke up twice with stabbing sole pain. Obviously it is killing something. I took it three times this week instead of twice to see what happens.
More than likely it is killing something in your brain and the toxins are causing your brain fog. I had really bad brain fog and emotional mood changes before but it is better now, not gone, but I feel I can function. Tindamax does not affect my mind.
Posted by TerryK (Member # 8552) on :
Tini can be hard on the liver. Have you had your liver enzymes checked lately? Do you have good liver support in place?
Seems like a good idea to pulse tini. My immune system isn't up to dealing with tini due a problem caused by excess zinc that I got from a defective product earlier this year but when I'm back to normal, I'll ask my LLMD if I can pulse tini.
I've been on nystatin everyday for a long time and it has been helpful but it is not a systemic yeast treatment. I don't know if nystatin protects against the fungus that causes the tini black tongue but I was on it everyday when I got the black tongue.
I take prophylactic over the counter anti-fungals everyday and have for a long time and even that didn't protect me.
Terry I'm not a doctor
Posted by steven (Member # 13101) on :
thanks, I will read about fungus, although at the moment i dont think this is the cause of my confusion. yes, I do have white tongue and dont know why, but this has been so for months and my tongue is not black. but anyway i will try diflucan again soon.
yes, could be a herx. but last time after tini/flagyl i had this for months - can a herx last for months...?
drug.com says confusion, vertigo and dizziness can be side effects of tini.
most llmd say tini isnt so strong as flagyl, but my experience is it is almost the same.
Posted by TerryK (Member # 8552) on :
There may be other reasons for a white tongue that I'm not aware of but mine has always been caused by a yeast infection candida which is a fungal infection.
Odd that your doctor didn't connect your symptoms to side effects of tini.
Take care, Terry I'm not a doctor
Posted by ticksickfamily (Member # 22786) on :
My son had a very bad reaction to tinidazole.Confused, blurry vision, very achy and it just got worse and worse. Our LLMD suspected Babesia in him but also a methylation/ detox problem for him, so she stopped it. Now 4 weeks later, we have had the Genova detoxi test results back and yes there is a significant methylation problem (COMT++ gene)for him plus a few other detox problems. So, not every reaction to a drug is a herx
Posted by vanbench19 (Member # 25328) on :
what do they recommend for the methylation detox problem?
Posted by ticksickfamily (Member # 22786) on :
We are just investigating this at the moment.There are several potential methylation gene problems. He has the COMT++ gene polymorphism. The only thing I have found so far is to eat mangoes, which he has been doing and feeling a little better.
Posted by TerryK (Member # 8552) on :
ticksickfamily and vanbench19 - I don't want to take this thread off it's main purpose but I have had the full Yasko workup for methylation. I have 3 COMT polymorphism's but there are many other SNP's included in her testing besides COMT. Not sure which one you and your son have.
With Yasko's work, treatment depends on your profile because some SNP's can modulate others. Yasko makes extensive supplement recommendations but she includes COMT enzyme recommendations with the ones that process vitamin D.
COMT's primary function is to break down dopamine but it is also involved in the breakdown of norepinephrine, epinephrine and in the proper processing of estrogen.��
The balance between dopamine and norepinephrine is implicated in ADD/ADHD. May be associated with bipolar disorder and panic disorder. Sensitivity to pain is correlated to COMT activity. COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma and parkinson's disease.
These are some of my notes but they are specific to my mutations.
COMT mutations will typically mean�increased levels of�dopamine because it is not broken down efficiently.
A few symptoms: Will need and tolerate lower amounts of methyl donors. The overuse of methyl donors could cause: Mood swings Irritability Hyperactivity erratic behavior
the more i think about this strange reaction i had on tini I am sure it was the combination of tini and mino that lead to this severe brainfog.
I think most of the time i took tini with mino in the past i got strange new neuro symptoms.
I know Burrascano recommends not to take flagyl or tini together with tetracyclines. I thought he did so because flagyl or tini makes tetras ineffective, but it may also have other reasons.
Posted by KH111 (Member # 25829) on :
I had no reaction to tinidazole and neither did my husband. I took this while pulsing zithromax for about 6 months. After that we did mepron, zith with arteminsin for 11 months. I would highly recommend tinidazole to break the cysts, or you will not recover.
Posted by stork (Member # 24167) on :
id say if you put the binders in place and are taking good detox supps and probiotics, stick with it. sounds more like a herx reaction to me.
yes - a herx's impact can effect you for months. i had one totally mess with my cognitive function. it was like night and day before and after it.
Posted by ticksickfamily (Member # 22786) on :
Terry K - Thanks for the information, I will look into it