This is topic Warning - Aquatic Doxy in forum Medical Questions at LymeNet Flash.


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Posted by juliet70 (Member # 32553) on :
 
SCROLL THROUGH WHOLE THREAD AS EXPIRED DOXY CAN BE TOXIC

YOU ALWAYS WANT TO KNOW THE DATE OF MANUFACTURE -DOXY SHOULD ONLY BE USED BY HUMANS INSIDE OF ONE YEAR OF THE DATE OF MANUFACTURE.


from Wikipedia:

Expired tetracyclines or tetracyclines allowed to stand at a pH less than 2 are reported to be nephrotoxic due to the formation of a degradation product, anhydro-4-epitetracycline <http://www.inchem.org/documents/ehc/ehc/ehc119.htm></Foye's Principles of Medicinal Chemistry; David A. Williams; William O. Foye, Thomas L. Lemke> causing Fanconi's syndrome <Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12ed, Laurence L. Brunton, Bruce A. Chabner, Bj�rn C. Knollmann>. In the case of doxycycline, the absence of an hydroxyl group in C-6 prevent the formation of the nephrotoxic compound <Foye's Principles of Medicinal Chemistry; David A. Williams; William O. Foye, Thomas L. Lemke>. Nevertheless, tetracyclines and doxycycline itself have to be taken with precaution in patients with kidney injury, as they can worsen azotemia due to catabolic effects <Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12ed, Laurence L. Brunton, Bruce A. Chabner, Bj�rn C. Knollmann>


Hi everyone!

I just wanted to share that my Amazon Aquatic doxy arrived today and the pills are identical to what I was prescribed by urgent care. Both are blue. Both say 'w-e-s-t-w-a-r-d 3142'

[ 07-07-2011, 02:11 PM: Message edited by: juliet70 ]
 
Posted by James1979 (Member # 31926) on :
 
Wow! Thanks a ton for sharing this!! [Smile]

Do they list an expiration date? It's very important that we don't take expired doxy. Thanks.
 
Posted by anonymiss (Member # 32018) on :
 
That's awesome! I am going to pick some up to keep on hand "just in case".
 
Posted by BoxerMom (Member # 25251) on :
 
OMG! When I read the title of your post, I thought you'd dropped your Doxy in the toilet!!

But you're treating with fish Doxy.

Soon enough, we'll all be treating with fish Doxy.

Good for you for being proactive. That's what it takes to save your life with this disease.

Let us know if you grow gills! HA!
 
Posted by Lymetoo (Member # 743) on :
 
Wow... just amazing. Yes, do make sure it's not expired. I think it's good for a year unless it's been sitting around next to an aquarium too long. [lol]

our new name for you:

FISH BAIT
 
Posted by juliet70 (Member # 32553) on :
 
Checking bottles now hang on... and BoxerMon - LOL!!!

Exp date = 01/2015

There are lot numbers too but I can't compare those to my 'human doxy' because they don't put that on the pill container!

I was sitting there last night going - what is the difference? Did some of these fall on the factory floor and get designated for aquarium use? There really is no discernible difference. Even the troubling "hyclate" added to the end of the word 'doxy' in the ingredients is just the long form name for the same stuff given to humans...or so says the internet.

In the meantime I'll be the guinea pig! I run out of 'real' doxy on Monday [Smile]
 
Posted by juliet70 (Member # 32553) on :
 
Should mention that of the many types for sale on Amazon I can only vouch for the one called 'Aquatic' with the pic of the purple fish on the white bottle.

fish bait
 
Posted by kidsgotlyme (Member # 23691) on :
 
You get doxy "hyclate" from the pharmacy too so don't worry about that.

We keep this on hand at all times too. It's the EXACT same thing.
 
Posted by James1979 (Member # 31926) on :
 
Juliet, this is very awesome! And thanks a lot for keeping us updated. [Smile]
 
Posted by James1979 (Member # 31926) on :
 
WARNING: Doxycycline is only safe for humans for 2 years after the manufacturing date!!! 2015 is WAY TOO FAR AWAY to be a safe expiration date for humans!!!! Google "doxycycline shelf life" for more info.

Juliet, does it say a manufacturing date anywhere? If it doesn't, then I really wouldn't take it. Old doxycycline will damage your kidneys, but also it won't work well as an antibiotic either. It's really not worth taking the risk! Maybe you can order some from over-seas?

I'm sending Juliet a PM so that she gets this message earlier.
 
Posted by juliet70 (Member # 32553) on :
 
No date of manufacture... [Frown]

Have an appt with an LLMD on July 12th so I'll bring it with me and ask.

Thanks for bringing this to our attention! Don't want to poison myself or others!
 
Posted by juliet70 (Member # 32553) on :
 
Just found this here....hard to know what the 2015 exp date is in reference to without knowing date of manufacture, so be warned I guess:

This was a post on a Shelf life of drugs thread found here:

http://www.pharmer.org/forum/discussion-prescription-and-otc-meds/shelf-life-rx

"While the majority of what captterry may be close to the truth, don't take internet advice as medical advice. Certain classes of drugs can kill you if they go past the expiration date.

One classical example is Doryx or (generic) doxycycline which is a tetracycline antibiotic.

Doxycycline's shelf life is a maximum of 2 years after manufacture which is consistant with the 1 year / 1 year hypothysis. Doxycycline is concentrated by the liver in the bile. It is also excreted in the urine.

But doxycycline will decompose after 2-3 years into toxic compound that has been shown to cause a dangerous syndrome resulting in damage to the kidneys and/or renal failure.

So while it may be safe(er) to take some meds longer than the expiration date certain classes of drugs (cyclines, opioids, etc) can hurt you and not just lose their potency."
 


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