This is topic MS....urgent in forum Medical Questions at LymeNet Flash.


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Posted by Marnie (Member # 773) on :
 
Regulation of Th1 and Th17 Cell Differentiation
and

Amelioration of Experimental Autoimmune
Encephalomyelitis by

Natural Product
Compound Berberine

http://www.jimmunol.org/content/185/3/1855.full.pdf

Experimental autoimmune encephalomyelitis is what is done to mice to mimic MS.

Berberine is available OTC from Amazon. It is not expensive.

It is also helpful to cure other things (infections, prostate cancer, etc.)

TALK TO YOUR DOCTOR!
 
Posted by Keebler (Member # 12673) on :
 
-
Marnie,

Thanks so much for that fantastic article.

And it's hot off the presses - today's date.

Chronic encephalomyelitis (whether directly from infection &/or autoimmune reactions from long-term chronic infection) seems to go right along on the ride with neuroborreliosis & other stealth infections.

In fact, ME (what "Chronic Fatigue Syndrome" is called in the UK and Canada) stands for "Myalgic Encephalomyelitis"

Berberine occurs in of many different herbs & foods. It's pretty amazing. I'd forgotten about it for a long time so I really appreciate this link.
-

[ 04-30-2012, 06:18 PM: Message edited by: Keebler ]
 
Posted by Keebler (Member # 12673) on :
 
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http://www.ncbi.nlm.nih.gov/pubmed?term=Berberine

PubMed Search of medical literature

Berberine � 2669 abstracts

Cross searching other terms:

Berberine, diabetes � 100 abstracts

Berberine, inflammation � 81 abstracts

Berberine, depression � 22 abstracts

Etc.

----------------------------

http://www.itmonline.org

Institute of Traditional Medicine

A research site for TCM, Traditional Chinese Medicine

Search: Berberine � 16 articles

-----------------------------

http://oneearthherbs.squarespace.com/

THE ONE EARTH HERBAL SOURCEBOOK (Tillotson, et.al.)

Search: BERBERINE � 5 reference pages

One of those discusses how

ALL SOURCES OF BERBERINE DO NOT HAVE THE EXACT EFFECTS

http://oneearthherbs.squarespace.com/important-herbs/phellodendron-bark-phellodendron-amurense.html

PHELLODENDRON BARK (Phellodendron amurense)

Excerpt:

The clinical differentiation among these three yellow TCM plants [which contain berberine] serves as an excellent argument against concentrating on a single chemical or group of chemical compounds in a plant.

While valuable at times, this practice can limit our perspective. It is tempting to make a general statement that all plants containing berberine are basically the same in their actions.

However, TCM doctors tell us that scute root is most useful for treating inflammation in the lungs and upper respiratory tract, including allergies.

On the other hand, coptis rhizome is useful for treating upper body inflammation, but not allergy. Rather, it is most effective when there is strong heat in the heart and other organs, high fever, and sore throat.

Phellodendron bark is more appropriate for treating inflammation in the lower parts of the body and for heat cause by deficiency. . . .

- full chapter at link above.

==========================================

Knowing when to call on which herb (or which FORMULA) can be very difficult for a lay person. It's good that we have lots of literature we can study but

it's best to consult with an ILADS-educated LL (lyme literate) doctor who has completed four years of post-graduate medical education in the field of herbal and nutritional medicine -

- and someone who is current with ILADS' research & presentations, past and present.
-----------------------

http://flash.lymenet.org/ubb/ultimatebb.php/topic/2/13964

How to find an ILADS-educated LL:

N.D. (Naturopathic Doctor);

L.Ac. (Acupuncturist);

D.Ay. (Doctor of Ayurvedic Medicine);

D.O.M. (Doctor of Oriental Medicine);

Integrative / Holistic M.D., etc. (Be aware that those in this category can have various levels of formal herbal &/or nutritional education, perhaps even just a short course. Do ask first.)
-

[ 05-02-2012, 02:05 PM: Message edited by: Keebler ]
 
Posted by canefan17 (Member # 22149) on :
 
Am I the only one who thinks MS/Parkinsons/ALS is mostly Bartonella in the CNS?
 
Posted by Keebler (Member # 12673) on :
 
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canefan,

I think various chronic stealth infections (and key deficiencies, heavy metals, chemical exposures, etc.) can be involved and, most likely, more than one at a time.

If you have one or two key articles that highlight Bartonella and CNS decline could you please add those on here?

I'd just like to know what information you've found to click on that light bulb for you, such as patients who were treated just for Bart also seeing a cure for other CNS Dx?

(Neutral voice tone here, not at all challenging you, just interested in research - or even just the name of an searchable author.)

Now, it may be that treatment for some diagnoses may also cover that for others, even if unidentified (or not).

Nicolson's article below may be of interest to you as he discusses various stealth infections' effect on the CNS.

---------------------

http://www.ilads.org/lyme_research/lyme_articles7.html

CONTROVERSIES IN NEUROBORRELIOSIS - by Audrey Stein Goldings, M.D.

Updated October, 2002 - Two page article

Discusses the relationship between MS and Borreliosis.

===============

http://www.cpnhelp.org/wheldon &

http://www.davidwheldon.co.uk/ms-treatment.html

Wheldon protocol for Cpn has helped many previously diagnosed with "MS"

=================

http://www.immed.org/illness/Neurodegenerative%20Diseases.html

Neurodegenerative and Neurobehavioral Diseases

- by Garth Nicolson, Ph.D.

Intracellular stealth infections are discussed as relative to MS and other neurological conditions.

===================

It's important to point out that researcher Alan MacDonald, MD found borrelia to be a common denominator in the majority of CNS cases he studied.

http://www.molecularalzheimer.org/

Molecular Alzheimer.org

======================

Again, it's great to see the article that Marnie posted about BERBERINE.
-

[ 04-30-2012, 06:25 PM: Message edited by: Keebler ]
 
Posted by Keebler (Member # 12673) on :
 
-
Thanks to HALEY for bringing this to our attention.
----------

http://flash.lymenet.org/scripts/ultimatebb.cgi/topic/1/113095?#000002

Topic: Doctor with MS recovers: shares nutrients & pivotal diet

Focus: "Minding My Mitochondria" by Terry Wahls, MD

"TED Talks" Video and book links.

MYELIN SHEATH & MITOCHONDRIA SUPPORT discussed.
-
 
Posted by sparkle7 (Member # 10397) on :
 
Berberine is good for alot of things... Check the article on Wikipedia (of all places).
 
Posted by Catgirl (Member # 31149) on :
 
Canefan, you're not alone. If not bart, then lyme.
 
Posted by Keebler (Member # 12673) on :
 
-
http://www.jneuroinflammation.com/content/9/1/72/abstract

23 April 2012 - Journal of Neuroinflammation

A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi
-
 
Posted by Marnie (Member # 773) on :
 
MS is triggered by a retroviral protein called HERV-W. That protein is needed to... get this... help implant the placenta.

And think about this...in mice engineered to have MS..prolactin spontaneously restored the myelin sheath (insulation around our nerves...from cholesterol). Prolactin is known primarily for its role in lactation(secretion of breast milk).

Is that retroviral protein (within us) cleaved off _ chopped off another longer protein via MMPs - metalloproteinases -> MS? Did an infection - epstein barr viral reactivation trigger the MMPs?

Get MMPs down OR find out how to stick that retroviral protein back on where it is supposed to be?

Agonist..."helpers"...google these words:

berberine agonist.
 


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