This is topic Artemisinin toxicity in forum Medical Questions at LymeNet Flash.


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Posted by lymeboy (Member # 24769) on :
 
I have just been told that I am taking way too much Art. 1800 per day. LLMD said that this can be toxic, and I should do half that. Anyone else take a high dose like that?
 
Posted by fourwinds (Member # 14114) on :
 
I'm curious why you are taking that much, especially if you are taking either Malarone or Mepron as well.

I know the higher doses are used for cancer treatment. But here is a concern :
http://tinyit.cc/28118

"Higher dosages in the range of 400 to 1000 mg, are suggested by many internet sites and a few

physicians. The problem with this approach is that the research has shown that within a very short time of use of high dosages, the body�s

inherent feedback mechanism reduces the intestinal absorption of the artemisinin by up to 70%. There is another very important

consequence to consider about taking high dosages of artemisinin: the whole idea of taking ART

compounds in the first place is to cause apoptosis to cancer cells, while leaving healthy cells alone; the possibility exists that if

excessive amounts of ART compounds are taken, there could be a spillover of artemisinin into healthy cells, with some resultant destruction to them."

I was just told to up my Artemisinin from 600 mg to 900 mg/day 4 days on, three days off and I'm a bit hesitant to take that much.

I've read dosages of 500-600 mg. I guess I'm curious if anyone else takes a gram or more per day (and are also on Mepron or Malarone).
 
Posted by lymeboy (Member # 24769) on :
 
jeez. I wonder if the Art makes me feel so awful because I take too much, and it isn't a herx.
 
Posted by Kristen J. (Member # 24566) on :
 
I felt good on 600mg a day. no side effects from that dosage.
 
Posted by fourwinds (Member # 14114) on :
 
quote:
Originally posted by lymeboy:
jeez. I wonder if the Art makes me feel so awful because I take too much, and it isn't a herx.

could be... I'd back down and see how you feel, JMO
 
Posted by mlg (Member # 35383) on :
 
Hi,

I take 1200-1600 mg a day for 3 days on wait 4 days off (take Crypto plus) per my LLMD. I also take Mepron.

Someone in my support group said he cleared his babesia and brain fog with higher doses of art. He suggested a book. You can pm me. I heard of people having sucess with this.
 
Posted by YinYang (Member # 36358) on :
 
I was told by my LLMD to not take Art with Mepron because they interact negatively with each other. I assume this isn't accurate??
 
Posted by Lauralyme (Member # 15021) on :
 
I take 400 mg a day
pulsed
3 weeks on
1 week off

My teeth could not tolerate grapefruit juice
Grapefruit juice prevents resistance
if grapefruit juice is not tolerated then it is to be pulsed
 
Posted by jupiter76 (Member # 37697) on :
 
Dr. K. a german physican who is mainly active in the US suggests taking Artemisinin 3x500mg/d for 3 days. When I started taking Artemisinin I felt really bad, now it is getting better. If someone is histamine intolerant ARtemisinin is a problem. This may be a problem in some cases.
 
Posted by lymeboy (Member # 24769) on :
 
Ive been doing high doses for almost a year and it is bad every time I pulse it. I take it with Mepron and a ton of other drugs
 
Posted by Jamers (Member # 28016) on :
 
Interesting Jupiter. I take 200 mg and any more than that and I get a histamine response...felt like I had severe allergies and swelling.
 
Posted by krk (Member # 34690) on :
 
I take 800 mg/day for 10 days, then off for 20 days. I was short of breath at first, but when I stopped at 10 days, I feel awful....migraine, achy joints and fatigue.

I also take it with Mepron and a ton of other drugs/supplements.
 


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