I got horribly ill from bioidentical hormones. Testing showed high eosinophils, so it may have been allergic in nature. It took me a month to figure out that it was the hormones making me sick, so just adding this in case, so someone else can figure it out more quickly. I don't know if it was hormones per se (it may have only been progesterone, I don't remember) or the oils used in making the cream.