Hi there, I just got tested for chlamydia and mycoplasma panels, which I have never had done before. The only one that came back positive was my Mycoplasma IgG at 445 ( normal is less than 100) Could anyone tell me what this means? Thank you!
Posted by Judie (Member # 38323) on :
It means you may have an active mycoplasma infection. Mine is up around the 1000. My doc says it's definitely active for me and judges by titers. Higher the titer=more active infection.
"In chronic infections, the level of activity of a microbe can be gauged to a certain extent by the amount of IgG antibodies your body produces in response to that microbe. High levels of IgG antibodies tend to suggest an active chronic infection."
I think IgG means you had an infection but it is not current. IgM means a recent active one.
Posted by Judie (Member # 38323) on :
Perhaps with typical infections, but not necessarily with these infections along with Lyme. Lyme tricks the immune system and other infections can reactivate.
When IgG is high with mycoplasma it can mean it reactivated which is what I experience because of my symptoms and my doc's interpretation.
Mycoplasma is difficult to get rid of, but it's hard to say what's going on with the OP since so many symptoms overlap.
Probably best to have the doc evaluate.
Posted by k84 (Member # 32738) on :
I have had my mycoplasma up at 450 IGG. Negative IGM always. After months of doxy or zith, it goes down to about 150, still positive (positive is greater then 100.
Switch protocols to hit other lyme co's (taking nothing that in theory hits mycoplasma) and mycoplasma jumps up to 250.
Posted by nefferdun (Member # 20157) on :
This is a little of subject, but what are you mycoplasma symptoms? Is it the same thing as BLO?
"Antibodies are produced by the immune system to fight antigens like bacteria and viruses. IgM refers to those antibodies that are produced immediately after an exposure to the disease, while IgG refers to a later response. IgG generally confers immunity to a patient so far as that particular disease is concerned."
With lyme IgG is a chronic infection.
Posted by Mathias (Member # 5298) on :
Don't ignore Mycoplasma. It needs to be treated just like lyme does and can become a chronic infection. One difference about mycoplasma is that to correctly treat it, it needs to be species typed. There are at least 4 pathogenic species: fermentans, pneumoniae, hominis and penetrans and the best antibiotics vary by species. They are very susceptible to floroquinlones.
Note that Mycoplasma fermentans is highly resistant to Biaxin and Zithromax.
Hope this helps. It took me many years to be successfully treated for mycoplasma.
Posted by bigz123 (Member # 23755) on :
Thanks for the reply, I was positive for pneumonia, so I am being put on Zithormycin along with my other bart meds. Good to know!
Posted by sparklyholiday (Member # 42456) on :
Curious... Were they specialty labs or were they covered by insurance?
Posted by Judie (Member # 38323) on :
Labcorp did mycoplasma pneumonia for me. Totally covered by insurance.
See my thread here on the tests and how I got my doc to run them.
This is the lab that was used for my testing. I'm not sure they test for all of the mycoplasma species anymore based on what I see on the their website.
Most common labs will test for mycoplasma pneumoniae but the IgM and IgG for mycoplasma species I believe cross react. I was IgG positive for pneumoniae but ended up being PCR tested positive for fermentans.
I was failing on Zithromax or Biaxin therapies at the time as well. Levaquin, Cipro and Factive all made a huge difference for me.
Posted by canefan17 (Member # 22149) on :
Thanks for the info Mathias
I couldn't take levaquin. Had to stop after 2 days. Factive and Cipro in same family right?
Posted by map1131 (Member # 2022) on :
Neff, sorry but chronic long term Lyme infection is usually seen in IgM. You might want to go back and read the research on how to read a western blot by Dr C on this website.
The majority of his chronic patients have positive IgM, the complete opposite of what tradional medicine says about IgG and IgM.
Once again its very important to have someone read your tests results that has a clue about this thing called Lyme & Co. Really just know how to look at the results but make more educated guesses at the real truth.
My PCP(medium knowledge of Lyme & Co) did some bacteria blood work on me and he was surprised my strep was high titers. He stated that was from past infection. No doc, don't believe that to be true.
I know better. I've known for years now my best rife treatments is running strep and staph. I feel better after doing them. I've never had staph swab taken of my nose. I keep forgetting to have that one done.
They too are super bacteria and that is why I have to repeat rife every so often on strep and staph to knock them down a notch or two. Of course they build their army back up and it's back at them again.
I took abx for years and it didn't touch the bad guys, including mycoplasma pN.