I believe this is what has happened to me this last month and a half. Been experiencing a bad skin rash, itchy and peeling. I quit biaxin three days ago because it was getting so bad.
This is what the author said "Many integrative practitioners, including myself, believe that a primary cause of histamine intolerance is an overgrowth of certain types of bacteria that make histamine from undigested food, leading to a buildup of histamine in the gut and overwhelming the body’s ability to catabolize the excess histamine.
This causes a heightened sensitivity to histamine-containing foods and an increase in symptoms that are commonly associated with allergies".
I believe the biaxin was causing an overgrowth of funky in my gut ,hence the hives like reaction. Have been taking 30billion probiotics twice a day. Something else to consider when going the ABX route. Thanks for posting lymetoo
[ 07-09-2014, 12:34 AM: Message edited by: Robin123 ]
Posted by Marnie (Member # 773) on :
Histamine is released as an allergic response to an antigen (protein).
It is also a neurotransmitter which is ***high in PD *** and schizo.
Rantinidine is zantac a H2 (histamine receptor) blocker.
Bismuth citrate is NOT "Pepto Bismol"...doesn't work the same.
MANY *foods* are high in histamine.
A fetus has to be protected from high levels of histamine which is why women make a copper (Cu) enzyme called DAO which goes up 500 fold during pregnancy.
After histamine is methylated by HNMT (me...if it is), it still needs further metabolism by DAO or MAO B.
In mammals, histamine is metabolized by two major pathways:
N(tau)-methylation via
histamine N-methyltransferase (HNMT)
and oxidative deamination via diamine oxidase (DAO)
This gene encodes the first enzyme which is found in the cytosol and
***uses S-adenosyl-L-methionine as the methyl donor.***
In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation
as diamine oxidase is not found in the central nervous system.
A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
Norcal, I would up the probiotics to at least 100 billion CFU's per day. I have found that Custom Probiotics' CP-1 is helpful. Some probiotics themselves will raise histamine levels. You can Google that for info.
My hives flared up when I went off my good candida diet for too long and was also under heavy stress. I do know that gut health makes a big difference.
Posted by Kudzuslipper (Member # 31915) on :
Very interesting Tutu. I am curious about the tritec Marnie. I know allergists in my past have suggested ranitidine or cimetidine for my allergic symptoms. I wonder if tritec could help me with my final symptoms.
Some very high histamine foods not mentioned soecifically are Strawberries, celery (huge) and sesame.
I think all allergies have a tipping point/ cumalitive effect like the article suggests of histamine.
Posted by ArtistDi (Member # 2297) on :
If there are high histamine levels, this could also point to a mast cell disorder.