Seeking advice on how to address MTHFR and other related SNP detox deficiencies.
I have done 23 and me and plugged my results into a couple of the free websites, and the results were... confusing and conflicting. I had no idea what to do with it, and neither does my LLMD.
I need more guidance.
Specifically, has anyone plunked down the money for the online Yasko personalized analysis? Is it helpful? Worth it? Ideally, I'd like to find something that lays it out for me and doesn't require me to do a lot of figuring out.
It looks like neither Yasko or Lynch do personal consults anymore. Can anyone recommend a practitioner who does do consults who knows what they are doing?
thank you!
Posted by MichaelTampa (Member # 24868) on :
Xymogen has a "Methyl Protect" product that is good for MTHFR. There are other brands with similar products. I believe Thorne has a 5MTHF product, which is the key nutrient that the body has difficulty making if you have MTHFR. The Xymogen product has 5MTHF plus other complimentary vitamins.
I haven't done the Yasko or any such protocols or consults, so can't speak to that.
Posted by bluelyme (Member # 47170) on :
See what snps were homozygous, and support as needed ...comt ,cbs ,mthfr ..the consult out of new zealand was very good
Posted by WPinVA (Member # 33581) on :
What was the consult out of New Zealand? Could you please PM me contact info?
I am actually looking for personalized support, not product recommendations. I understand the basics of MTHFR but need help with the intricacies....most SNPs are heterozygous and the online advice is conflicting. And I need someone to look at my SNPs and advise on taking methyl B12 vs Hydroxy B12, which SNP to correct first, etc.
thanks!
[ 08-29-2016, 10:44 AM: Message edited by: WPinVA ]
Posted by WakeUp (Member # 9977) on :
Even scientists don't know exactly why things like Prozac work. I just plunged in and took this supplement and I soon found out that it works great for me: (all you really have to lose is $19:
Active B12 Lozenge With L-5-MTHF | 800 mcg of Pure Non-racemic L-methylfolate
But amazingly I stopped needing it ---when I when on a fully raw diet last month...
Posted by ukcarry (Member # 18147) on :
I have read conflicting opinions about the usefulness of Yasko's views on methylation. I agree that it is a good idea to find a well-reviewed practitioner to guide you through your results because they are in a position to see 'the bigger picture' when they look at your results as a whole.
Hope you find someone good.
Posted by WPinVA (Member # 33581) on :
Thanks, it's a lot of $ to plunk down when you're not even getting to talk with a live person. Still, if I hear some personal positive reviews and don't have a better option, I would likely do it.
Posted by sillia (Member # 23994) on :
WP, since you've done the 23andme test, you don't need to pay for Dr. Yasko's DNA testing. You can plug your data in at her website, KnowYourGenetics.com, and get the same information back. There is a lot of information in there, including supplement suggestions.
This document should allow you to figure out which kind of B12 she advises. My marker of COMT V158M +/+ along with VDR Taq -/- indicates mostly hydroxy B12 is tolerated (according to Yasko). It also indicates I'm extremely sensitive to methyl donors which helps me understand now why so many treatments I've tried didn't seem to help.
Dr. Yasko's program is comprehensive--it's not a matter of take this for that, it's building up your system gradually and getting the machinery to work right. She is working mainly with autistic children now. A doctor in California works with adults using the Yasko program and sees patients. This looks too expensive for me. but you can inquire at NancyMullanMD.com.
I am in the first stages of the Yasko program and it's way more expensive than I thought it would be. It's also very frustrating to find out what to do, as they just are not set up to help people with cognitive function problems who can't read and synthesize material. You're expected to study.
Nonetheless, I plan to persevere as I am seeing progress and I am convinced I need to do this. I need the comprehensive aspect, I don't think I will ever get well just "trying" things to see if they work.
Posted by Tincup (Member # 5829) on :
I had the yasko test years ago. Don't know what it's like now but back then it told me exactly what to take and why.
Biggest thing to know is if you have something you need to treat before you treat MTHFR like sulfur (CBS upregulation). Otherwise you can make yourself sicker.
Her discussion group used to be very helpful. Free to join. I assume it is still useful.