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Author Topic: Altered Immunity & The Leaky Gut Syndrome
Melanie Reber
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This is actually one of the best Leaky Gut articles that I have read.

And could be an explanation for my continued edema and allergies.

________________________________________


Leaky Gut syndrome is the suspected cause of many of the "untreatable" chronic diseases today. This article by Dr. Zoltan P Rona provides a valuable source of information on the syndrome.

Altered Immunity & The Leaky Gut Syndrome

by Dr Zoltan P Rona MD, MSc

The leaky gut syndrome is a name given to a very common health disorder in which the basic organic defect (lesion) is an intestinal lining which is more permeable (porous) than normal. The abnormally large spaces present between the cells of the gut wall allow the entry of toxic material into the blood stream that would, in healthier circumstances, be repelled and eliminated.

The gut becomes leaky in the sense that bacteria, fungi, parasites and their toxins, undigested protein, fat and waste normally not absorbed into the bloodstream in the healthy state, pass through a damaged, hyperpermeable, porous or "leaky" gut.. This can be verified by special gut permeability urine tests, microscopic examination of the lining of the intestinal wall as well as the bloodstream with phase contrast or darkfield microscopy of living whole blood.

Why is leaky gut syndrome important? The leaky gut syndrome is almost always associated with autoimmune disease and reversing autoimmune disease depends on healing the lining of the gastrointestinal tract. Any other treatment is just symptom suppression. An autoimmune disease is defined as one in which the immune system makes antibodies against its own tissues. Diseases in this category include lupus, alopecia, rheumatoid arthritis, polymyalgia rheumatica, multiple sclerosis, fibromyalgia, chronic fatigue syndrome, Sjogren's syndrome, vitiligo, thyroditis, vasculitis, Crohn's disease, ulcerative colitis, urticaria (hives), diabetes and Raynaud's disease.

Physicians are increasingly recognizing the importance of the gastrointestinal tract in the development of allergic or autoimmune disease. Understanding the leaky gut phenomenon not only helps us with safe and effective therapies to bring the body back into balance. Due to larger than normal spaces between the cells of the gut wall, larger than usual protein molecules are absorbed before they have a chance to be completely broken down as occurs when the intestinal lining is intact. The immune system starts making antibodies against these larger molecules because it recognizes them as foreign, invading substances. The immune system starts treating them as if they had to be destroyed. Antibodies are made against these proteins derived from previously harmless foods. Human tissues have antigenic sites very similar to those on foods, bacteria, parasites, candida or fungi.

The antibodies created by the leaky gut phenomenon against these antigens can get into various tissues and trigger an inflammatory reaction when the corresponding food is consumed or the microbe is encountered. Autoantibodies are thus created and inflammation becomes chronic. If this inflammation occurs at a joint, autoimmune arthritis (rheumatoid arthritis) develops. If it occurs in the brain, myalgic encephalomyletis (a.k.a. chronic fatigue syndrome) may be the result. If it occurs in the blood vessels, vasculitis (inflammation of the blood vessels) is the resulting autoimmune problem. If the antibodies start attacking the lining of the gut itself, the result may be colitis or Crohn's disease. If it occurs in the lungs, asthma is triggered on a delayed basis every time the individual consumes the food which triggered the production of the antibodies in the first place. It is easy to see that practically any organ of the body tissue can become affected by food allergies created by the leaky gut. Symptoms, especially those seen in conditions such as chronic fatigue syndrome, can be multiple and severely debilitating.

The inflammation that causes the leaky gut syndrome also damages the protective coating of the IgA family normally present in a healthy gut. Since IgA helps us ward off infections, with leaky gut problems we become less resistant to viruses, bacteria, parasites and candida. These microbes are then able to invade the bloodstream and colonize almost any body tissue or organ. When this occurs in the gums, periodontal disease results. If it happens in the jaw, tooth extraction or root canals might be necessary to cure infection.

In addition to the creation of food allergies by the leaky gut, the bloodstream is invaded by bacteria, fungi and parasites that, in the healthy state, would not penetrate the protective barrier of the gut. These microbes and their toxins, if present in large enough amounts, can overwhelm the liver's ability to detoxify. This results in syndromes such as confusion, memory loss, brain fog, or facial swelling when the individual is exposed to a perfume or to cigarette smoke that he or she has had no adverse reactions to prior to the development of leaky gut syndrome.

Leaky gut syndrome also creates a long list of mineral deficiencies because the various carrier proteins present in the gastrointestinal tract that are need to transport minerals to the blood are damaged by the inflammation process. For example, magnesium deficiency (low red blood cell magnesium) is quite a common finding in conditions like fibromyalgia despite a high magnesium intake through the diet and supplementation. If the carrier protein for magnesium is damaged, magnesium deficiency develops as the result of malabsorption. Muscle pain and spasms can occur as a result. Similarly, zinc deficiency due to malabsorption can result in hair loss or baldness as occurs in alopecia areata. Copper deficiency can occur in an identical way leading to high blood cholesterol levels and osteoarthritis. Further, bone problems develop as a result of the malabsorption of calcium, boron, silicon and manganese.

The Causes

The leaky gut syndrome is basically caused by the inflammation of the gut lining. This inflammation is usually brought about by the following:
Antibiotics because they lead to the overgrowth of abnormal flora in the gastrointestinal tract (bacteria, parasites, candida, fungi; alcohol and caffeine (strong gut irritants):

foods and beverages contaminated by parasites like giardia lamblia, cryptosporidium, blastocystis hominis and other food and beverage contaminated by bacteria like helicobacter pylori, klebsiella, citrobacter, pseadomoas and other chemicals in fermented and processed food (dyes, preservatives, peroxidized fats);

enzyme deficiencies (e.g. celiac disease, lactase deficiency causing lactose intolerance) NSAIDS (non-steriodal anti-inflammatory drugs) like ASA, ibuprofen, indomethancin, etc);

prescription corticosteroids (e.g. prednisone);

high refined carbohydrate diet - (e.g. candy bars, cookies, cake, soft drinks, white bread);

prescription hormones like birth control pills;

mold and fungal mytoxins in stored grains, fruit nad refined carbohydrates.


The leaky gut syndrome can cause the malabsorption of many important micronutrients. The inflammatory process causes swelling (edema) and the presence of many noxious chemicals all of which can block the absorption of vitamins and essential amino acids. A leaky gut does not absorb the nutrients properly. Bloating, gas and cramps occur as do a long list of vitamin and mineral deficiencies. Eventually, systemic complaints like fatigue, headaches, memory loss, poor concentration or irritability develop.

Prescription broad spectrum antibiotics, especially when taken for extended periods of time, wipe out all the gut friendly bacteria that provide protection against fungi and amoebic (parasitic) infections, help the body break down complex foods and synthesize vitamins like B12 and biotin. Since the friendly bowel flora is killed off, the body now has no local defense against parasites or fungi that are normally held in check. This then quickly develop and these may trigger the signs and symptoms of arthritis, eczema, migraines, asthma or other forms of immune dysfunction. Other common symptoms of this bowel flora imbalance and leaky gut syndrome are bloating and gas after meals and alternating constipation and diarrhea. This set of symptoms is usually labeled as IBS (irritable bowel syndrome) or spastic bowel disease and treated symptomatically by general practitioners and gastroenterologists with antispasmodic drugs, tranquilizers or different types of soluble (pysllium) and insoluble (bran) fiber.

The Leaky Gut and IBS

The mainstream thinking on IBS is that it is caused by stress. Irritable Bowel Syndrome is the number one reason for general practitioner referrals to specialists. In well over 80% of the cases, tests like intestinal permeability test ( a special urine test involving the determination of the absorption rates of two sugars called lactulose and mannitol), CDSA or livecell darkfield microscopy reveal the presence of an overgrowth of fungi, parasites or pathogenic bacteria. The one celled parasite, blastocystis hominis and different species of candida are the most common microbes seen in IBS. The only stress associated with IBS is that which is generated by leaky gut syndrome. If allowed to persist without correct treatment, IBS can progress into more serious disorders like the candidasis syndrome, multiple chemical sensitivities, chronic fatigue syndrome, many autoimmune diseases and even cancer. If treated medically, IBS is rarely cured. To treat it correctly, natural treatments work best and must include the removal of the cause, improvement of gastrointestinal function and healing the lining of the gut.

How to reverse Leaky Gut syndrome

Band-aid treatment with corticosteroids, prescription antibiotics and immunosuppressive drugs may be temporarily life saving for acute episode of pain, bleeding or severe inflammation as occurs in lupus or colitis. In the long run, however, none of these treatments do anything to heal the leaky gut problem. To reverse the leaky gut syndrome the diet must be completely changed to one which is as hypoallergenic as possible. Sugar, white flour products, all gluten containing grains (especially wheat, barley, oats and rye), milk and dairy products, high fat foods, caffeine products, alcohol and hidden food allergies determined by testing must all be eliminated for long periods of time (several years in the more severe cases).
Treatment might also include the use of natural antibiotics: (echinacea, colloidal silver, garlic), antiparasitics:(cloves, wormwood, black walnut) and antifungal (taheebo, caplytic acid, grapefruit seed extract) depending on the type of infection which shows up on objective tests. It is rare that victims require prescription drugs for these infections and they should be discouraged. The drugs are usually expensive, have unpleasant side effects and are best reserved for life threatening conditions. Leaky gut syndrome patients can help themselves by chewing their food more thoroughly, following the basic rules of food combining, eating frequent small meals rather than three large ones and taking more time with their meals. Gastrointestinal function can be improved with a juice fast or a hypoallergenic diet and supplements like lactobacillus acidophilus and bifidus as well as FOS (fructooligosaccharides) derived from Jerusalem artichoke, chicory, the dahlia plant or burdock root.

Beneficial supplements for leaky gut syndrome.

Natural digestive enzymes - from plant (e.g. bromelain, papain) or pancreatic animal tissues (porcine, bovine, lamb) and aloe vera juice with high MPS concentration (good brands are International Aloe, Earthnet and Royal);

stomach enhancing supplements- betain and pepsin, glutamic acid, stomach bitters, apple cider vinegar; amino acids - L-glutamine, N-acetyl-glucosamine (NAG)

essential fatty acids - milled flax, flax seed oil, evening primrose oil, borage oil, olive oil, fish oil, black current seed oil; soluble fiber - pysillium seed husks and powder, apple and citrus pectin, the rice derived gamma oryzanol;

antioxidants- carotenoids, B complex. vitamin C, E, zinc, selenium, germanium, coenzyme Q10, bioflavinoids, especially quercetin, catechin, hesperidin, rutin and proanthocyanidins (pycnogonals, grape seed extract, pine bark extract, bilberry; herbs

and plant extracts - kudzu, various high chlorophyll containing green drinks like spirulina, chlorella and blue-green algae, burdock, slippery elm, Turkish rhubarb, sheep sorrel, licorice root, ginger root, goldenseal, bismuth and bentonite.

Combination Green Foods - two excellent products are Green Life (bioquest) and Greens+ (Supplement Plus).


Due to the increasing recognition of chronic fatique syndrome, the leaky gut syndrome and multiple chemical sensitivity, a number of supplement companies have been marketing powdered hypoallergenic formulations containing most of the nutrients mentioned above in one convenient package. Some brand names include UltrabalanceB, UltraClear, SustainB, UltraClear PlusB, Pro-Cleanse, Pro-Support, and AntiClear. The products are only available through natural health practitioners like chiropractors, nutritional doctors and naturopaths.

If you suspect you may be suffering from leaky gut syndrome, the most important thing to do is get yourself tested by a natural health care practitioner. A personalized natural program of diet and supplements can then be instituted to help you reverse this debilitating condition.

References:

Gittleman, A L - Guess what came to Dinner - parasites and your health. Garden City Park, NY Avery 1993.
Gottchall, Elain. Breaking the vicious Cycle. Intestinal Health through diet. Kirkton, Ont, Kirkton Press 1994
Martin, Jeanne Marie and Rona, Zoltan P. The complete Candida Yeast Guidebook. Rocklin, California. Prima Books 1996
Robert L et al. The effects of procyandolic oligomers on vascular permeability. A study using quantitative morphology. Pathol Biol. 38.608-616: 1990
Rogers, Sherry A. Finally Healing the immune System. Macrobiotics Today. Sept/Oct 1995 pp 16-20

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Annthenurse
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I have a true strory. I have been on Oasis Life Sciences products for over a year. I am at least 95% better since starting them. My Chiropractor told me about one of his patients who had a hole in his intestine. The doctor wanted to do a colostomy on him. My Chiropractor suggested he ask his MD to put him on antibiotics and started taking Ageless Extra and Aloe Gold three times a week. In a short time he went back to see his MD and had additional tests. The hole is gone. I believe he probably had leaky gut. These products are fantastic. go to www.oasislifesciences.com
Ann

--------------------
Ann

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trueblue
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Thanks for posting this Melanie.

--------------------
more light, more love
more truth and more innovation

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Melanie Reber
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Thanks for the added information Ann.

You are very welcome Blue.


*Just as a side note on editing*

Betty asked me to edit this for her, so I will, this time.

Personally, I have a difficult time reading text that is over-edited.

My eyes will not track consistently sized paragraphs well. So, I do not edit my posts that way in general.

I know that we all have our own preferences on this...so from now on, I would suggest that if you would like the text editied to suit your preference, that you do so yourself.

My best,
Melanie

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Melanie Reber
Frequent Contributor (5K+ posts)
Member # 3707

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Leaky Gut syndrome is the suspected cause of many of the "untreatable" chronic diseases today. This article by Dr. Zoltan P Rona provides a valuable source of information on the syndrome.

Altered Immunity & The Leaky Gut Syndrome

by Dr Zoltan P Rona MD, MSc

The leaky gut syndrome is a name given to a very common health disorder in which the basic organic defect (lesion) is an intestinal lining which is more permeable (porous) than normal.

The abnormally large spaces present between the cells of the gut wall allow the entry of toxic material into the blood stream that would, in healthier circumstances, be repelled and eliminated.

The gut becomes leaky in the sense that bacteria, fungi, parasites and their toxins, undigested protein, fat and waste normally not absorbed into the bloodstream in the healthy state, pass through a damaged, hyperpermeable, porous or "leaky" gut..

This can be verified by special gut permeability urine tests, microscopic examination of the lining of the intestinal wall as well as the bloodstream with phase contrast or darkfield microscopy of living whole blood.

Why is leaky gut syndrome important? The leaky gut syndrome is almost always associated with autoimmune disease and reversing autoimmune disease depends on healing the lining of the gastrointestinal tract.

Any other treatment is just symptom suppression. An autoimmune disease is defined as one in which the immune system makes antibodies against its own tissues. Diseases in this category include lupus, alopecia, rheumatoid arthritis, polymyalgia rheumatica, multiple sclerosis, fibromyalgia, chronic fatigue syndrome, Sjogren's syndrome, vitiligo, thyroditis, vasculitis, Crohn's disease, ulcerative colitis, urticaria (hives), diabetes and Raynaud's disease.

Physicians are increasingly recognizing the importance of the gastrointestinal tract in the development of allergic or autoimmune disease. Understanding the leaky gut phenomenon not only helps us with safe and effective therapies to bring the body back into balance.

Due to larger than normal spaces between the cells of the gut wall, larger than usual protein molecules are absorbed before they have a chance to be completely broken down as occurs when the intestinal lining is intact. The immune system starts making antibodies against these larger molecules because it recognizes them as foreign, invading substances.

The immune system starts treating them as if they had to be destroyed. Antibodies are made against these proteins derived from previously harmless foods. Human tissues have antigenic sites very similar to those on foods, bacteria, parasites, candida or fungi.

The antibodies created by the leaky gut phenomenon against these antigens can get into various tissues and trigger an inflammatory reaction when the corresponding food is consumed or the microbe is encountered. Autoantibodies are thus created and inflammation becomes chronic.

If this inflammation occurs at a joint, autoimmune arthritis (rheumatoid arthritis) develops. If it occurs in the brain, myalgic encephalomyletis (a.k.a. chronic fatigue syndrome) may be the result. If it occurs in the blood vessels, vasculitis (inflammation of the blood vessels) is the resulting autoimmune problem.

If the antibodies start attacking the lining of the gut itself, the result may be colitis or Crohn's disease. If it occurs in the lungs, asthma is triggered on a delayed basis every time the individual consumes the food which triggered the production of the antibodies in the first place.

It is easy to see that practically any organ of the body tissue can become affected by food allergies created by the leaky gut. Symptoms, especially those seen in conditions such as chronic fatigue syndrome, can be multiple and severely debilitating.

The inflammation that causes the leaky gut syndrome also damages the protective coating of the IgA family normally present in a healthy gut. Since IgA helps us ward off infections, with leaky gut problems we become less resistant to viruses, bacteria, parasites and candida.

These microbes are then able to invade the bloodstream and colonize almost any body tissue or organ. When this occurs in the gums, periodontal disease results. If it happens in the jaw, tooth extraction or root canals might be necessary to cure infection.

In addition to the creation of food allergies by the leaky gut, the bloodstream is invaded by bacteria, fungi and parasites that, in the healthy state, would not penetrate the protective barrier of the gut.

These microbes and their toxins, if present in large enough amounts, can overwhelm the liver's ability to detoxify. This results in syndromes such as confusion, memory loss, brain fog, or facial swelling when the individual is exposed to a perfume or to cigarette smoke that he or she has had no adverse reactions to prior to the development of leaky gut syndrome.

Leaky gut syndrome also creates a long list of mineral deficiencies because the various carrier proteins present in the gastrointestinal tract that are need to transport minerals to the blood are damaged by the inflammation process.

For example, magnesium deficiency (low red blood cell magnesium) is quite a common finding in conditions like fibromyalgia despite a high magnesium intake through the diet and supplementation. If the carrier protein for magnesium is damaged, magnesium deficiency develops as the result of malabsorption. Muscle pain and spasms can occur as a result.

Similarly, zinc deficiency due to malabsorption can result in hair loss or baldness as occurs in alopecia areata. Copper deficiency can occur in an identical way leading to high blood cholesterol levels and osteoarthritis. Further, bone problems develop as a result of the malabsorption of calcium, boron, silicon and manganese.

The Causes

The leaky gut syndrome is basically caused by the inflammation of the gut lining. This inflammation is usually brought about by the following:

Antibiotics because they lead to the overgrowth of abnormal flora in the gastrointestinal tract (bacteria, parasites, candida, fungi; alcohol and caffeine (strong gut irritants):

foods and beverages contaminated by parasites like giardia lamblia, cryptosporidium, blastocystis hominis and other food and beverage contaminated by bacteria like helicobacter pylori, klebsiella, citrobacter, pseadomoas and other chemicals in fermented and processed food (dyes, preservatives, peroxidized fats);

enzyme deficiencies (e.g. celiac disease, lactase deficiency causing lactose intolerance) NSAIDS (non-steriodal anti-inflammatory drugs) like ASA, ibuprofen, indomethancin, etc);

prescription corticosteroids (e.g. prednisone);

high refined carbohydrate diet - (e.g. candy bars, cookies, cake, soft drinks, white bread);

prescription hormones like birth control pills;

mold and fungal mytoxins in stored grains, fruit nad refined carbohydrates.


The leaky gut syndrome can cause the malabsorption of many important micronutrients. The inflammatory process causes swelling (edema) and the presence of many noxious chemicals all of which can block the absorption of vitamins and essential amino acids.

A leaky gut does not absorb the nutrients properly. Bloating, gas and cramps occur as do a long list of vitamin and mineral deficiencies. Eventually, systemic complaints like fatigue, headaches, memory loss, poor concentration or irritability develop.

Prescription broad spectrum antibiotics, especially when taken for extended periods of time, wipe out all the gut friendly bacteria that provide protection against fungi and amoebic (parasitic) infections, help the body break down complex foods and synthesize vitamins like B12 and biotin.

Since the friendly bowel flora is killed off, the body now has no local defense against parasites or fungi that are normally held in check. This then quickly develop and these may trigger the signs and symptoms of arthritis, eczema, migraines, asthma or other forms of immune dysfunction.

Other common symptoms of this bowel flora imbalance and leaky gut syndrome are bloating and gas after meals and alternating constipation and diarrhea. This set of symptoms is usually labeled as IBS (irritable bowel syndrome) or spastic bowel disease and treated symptomatically by general practitioners and gastroenterologists with antispasmodic drugs, tranquilizers or different types of soluble (pysllium) and insoluble (bran) fiber.

The Leaky Gut and IBS

The mainstream thinking on IBS is that it is caused by stress. Irritable Bowel Syndrome is the number one reason for general practitioner referrals to specialists. In well over 80% of the cases, tests like intestinal permeability test ( a special urine test involving the determination of the absorption rates of two sugars called lactulose and mannitol), CDSA or livecell darkfield microscopy reveal the presence of an overgrowth of fungi, parasites or pathogenic bacteria.

The one celled parasite, blastocystis hominis and different species of candida are the most common microbes seen in IBS. The only stress associated with IBS is that which is generated by leaky gut syndrome. If allowed to persist without correct treatment, IBS can progress into more serious disorders like the candidasis syndrome, multiple chemical sensitivities, chronic fatigue syndrome, many autoimmune diseases and even cancer. If treated medically, IBS is rarely cured.

To treat it correctly, natural treatments work best and must include the removal of the cause, improvement of gastrointestinal function and healing the lining of the gut.

How to reverse Leaky Gut syndrome

Band-aid treatment with corticosteroids, prescription antibiotics and immunosuppressive drugs may be temporarily life saving for acute episode of pain, bleeding or severe inflammation as occurs in lupus or colitis.

In the long run, however, none of these treatments do anything to heal the leaky gut problem. To reverse the leaky gut syndrome the diet must be completely changed to one which is as hypoallergenic as possible. Sugar, white flour products, all gluten containing grains (especially wheat, barley, oats and rye), milk and dairy products, high fat foods, caffeine products, alcohol and hidden food allergies determined by testing must all be eliminated for long periods of time (several years in the more severe cases).

Treatment might also include the use of natural antibiotics: (echinacea, colloidal silver, garlic), antiparasitics:(cloves, wormwood, black walnut) and antifungal (taheebo, caplytic acid, grapefruit seed extract) depending on the type of infection which shows up on objective tests.

It is rare that victims require prescription drugs for these infections and they should be discouraged. The drugs are usually expensive, have unpleasant side effects and are best reserved for life threatening conditions. Leaky gut syndrome patients can help themselves by chewing their food more thoroughly, following the basic rules of food combining, eating frequent small meals rather than three large ones and taking more time with their meals.

Gastrointestinal function can be improved with a juice fast or a hypoallergenic diet and supplements like lactobacillus acidophilus and bifidus as well as FOS (fructooligosaccharides) derived from Jerusalem artichoke, chicory, the dahlia plant or burdock root.

Beneficial supplements for leaky gut syndrome.

Natural digestive enzymes - from plant (e.g. bromelain, papain) or pancreatic animal tissues (porcine, bovine, lamb) and aloe vera juice with high MPS concentration (good brands are International Aloe, Earthnet and Royal);

stomach enhancing supplements- betain and pepsin, glutamic acid, stomach bitters, apple cider vinegar; amino acids - L-glutamine, N-acetyl-glucosamine (NAG)

essential fatty acids - milled flax, flax seed oil, evening primrose oil, borage oil, olive oil, fish oil, black current seed oil; soluble fiber - pysillium seed husks and powder, apple and citrus pectin, the rice derived gamma oryzanol;

antioxidants- carotenoids, B complex. vitamin C, E, zinc, selenium, germanium, coenzyme Q10, bioflavinoids, especially quercetin, catechin, hesperidin, rutin and proanthocyanidins (pycnogonals, grape seed extract, pine bark extract, bilberry; herbs

and plant extracts - kudzu, various high chlorophyll containing green drinks like spirulina, chlorella and blue-green algae, burdock, slippery elm, Turkish rhubarb, sheep sorrel, licorice root, ginger root, goldenseal, bismuth and bentonite.

Combination Green Foods - two excellent products are Green Life (bioquest) and Greens+ (Supplement Plus).


Due to the increasing recognition of chronic fatique syndrome, the leaky gut syndrome and multiple chemical sensitivity, a number of supplement companies have been marketing powdered hypoallergenic formulations containing most of the nutrients mentioned above in one convenient package.

Some brand names include UltrabalanceB, UltraClear, SustainB, UltraClear PlusB, Pro-Cleanse, Pro-Support, and AntiClear. The products are only available through natural health practitioners like chiropractors, nutritional doctors and naturopaths.

If you suspect you may be suffering from leaky gut syndrome, the most important thing to do is get yourself tested by a natural health care practitioner. A personalized natural program of diet and supplements can then be instituted to help you reverse this debilitating condition.

References:

Gittleman, A L - Guess what came to Dinner - parasites and your health. Garden City Park, NY Avery 1993.

Gottchall, Elain. Breaking the vicious Cycle. Intestinal Health through diet. Kirkton, Ont, Kirkton Press 1994

Martin, Jeanne Marie and Rona, Zoltan P. The complete Candida Yeast Guidebook. Rocklin, California. Prima Books 1996

Robert L et al. The effects of procyandolic oligomers on vascular permeability. A study using quantitative morphology. Pathol Biol. 38.608-616: 1990

Rogers, Sherry A. Finally Healing the immune System. Macrobiotics Today. Sept/Oct 1995 pp 16-20

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stella marie
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Thanks Melanie great article! Where did you find this and is there a link?

Yes, I too find if writing is over edited I have a hard time reading it and skip it entirely. Can't follow a darn line if written that way.

Stella Marie

--------------------
Stella Marie

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treepatrol
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quote:
Originally posted by stella marie:
Thanks Melanie great article! Where did you find this and is there a link?

Yes, I too find if writing is over edited I have a hard time reading it and skip it entirely. Can't follow a darn line if written that way.

Stella Marie

health-n-energy

--------------------
Do unto others as you would have them do unto you.
Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.

Newbie Links

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stella marie
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Thanks Tree!

--------------------
Stella Marie

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luvs2ride
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This is what I have been trying to tell everyone.

Change of diet had more impact on improving my symptoms than anything else I have done. This told me I had to have leaky gut syndrome.

My doctor ran tests to prove what I suspected and now I am focused on healing my gut and removing all the fungus etc that has escaped into my body and may very well be the cause of my rheumatoid arthritis.

I believe the homeopathy I did originally cleared up all my lyme symptoms and that the RA may be coming from other sources like my gut, my infected root canals and my heavy metals.

We need to look beyond just the lyme. Lyme may be the original infection, but it allows so many other things to take up residence in our bodies and longterm antibiotic use is the number one cause of leaky gut.

--------------------
When the Power of Love overcomes the Love of Power, there will be Peace.

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elle
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From your article . . . .

"The inflammation that causes the leaky gut syndrome also damages the protective coating of the IgA family normally present in a healthy gut. Since IgA helps us ward off infections, with leaky gut problems we become less resistant to viruses, bacteria, parasites and candida. These microbes are then able to invade the bloodstream and colonize almost any body tissue or organ. When this occurs in the gums, periodontal disease results. If it happens in the jaw, tooth extraction or root canals might be necessary to cure infection."


Our pediatrician, put our twins on miralax, when they were 6 yo for IBS . . . They wer going to move to zelnorm later but we changed peds. All my children have stomach issues from time to time. I was dx as IBS, divticulitis, colitis at the Mayo - 2 years ago. I used to take zelnorm, miralax and pain meds.

It wasn't until after I got lyme and had my children tested and we started digging into the allergies that we found that much of our family is selective IgA deficient.

You would think that instead of the medical community throwing treatments at every symptom and disease, they would work on the causal problem.

A selective IgA deficiency is no fun but it only requires a simple blood test and most doctors don't run it even with a dx of leaky gut, IBS, colitis, etc. .


This doesn't mean that all people with digestive problems have IgA deficeincies . . . but many do. I went for years thinking it had to do with what I ate, how I ate, what I didn't eat, the time I ate . . . yada, yada, yada . . .


Elle

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luvs2ride
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Elle,

What you say is so sad, but so true.

Mainstream medical doctors are not trained to look for causes. They only know how to medicate symptoms which may make us feel good for a time but eventually the cause appears in other areas of our bodies.

I don't fault the doctors, I fault our medical schools.

There are many doctors today who have branched out and learned how to seek causes and treat the body as a whole, not as individual and disconnected parts.

These doctors usually label their practice as "intergrative care" as they integrate their western training with more traditional alternative care.

These are the only doctors I choose to work with.

When I tested high in my RA factor, my LLMD told me to see a rheumatologist. Even though there is a lot of scientific evidence of a bacterial cause to RA, the rheumy did not test for any of these causes. Nor did he discuss my diet or leaky gut and changing my diet made the most improvement in my pain.

Rheumy just wanted to put me on Methotrexate which is an immuno-suppressant. I knew this would be bad news with my lyme, so on my own I researched and found the evidence of bacterial cause to RA and a very safe abx treatment of minocycline 100mg pulsed MWF. I begged the Rheumy to prescribe this treatment and he did.

Why did I have to be the one to uncover this connection?

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trueblue
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quote:
Originally posted by elle:
A selective IgA deficiency is no fun but it only requires a simple blood test and most doctors don't run it even with a dx of leaky gut, IBS, colitis, etc. .


This doesn't mean that all people with digestive problems have IgA deficeincies . . . but many do. I went for years thinking it had to do with what I ate, how I ate, what I didn't eat, the time I ate . . . yada, yada, yada . . .


Elle

Sorry sort of Off Topic...

Elle,
What was done for the IgA deficiency?
Someone's finally thought to test me for immune complexes and IgA and IgM come up very low. I recieved no explanation but in searching found that IgA is often involved with allergic responses, etc..


Ok, back to our regualrly scheduled program...
[Big Grin]

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more truth and more innovation

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TheCrimeOfLyme
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Thank you for the article melanie.

Luvs2Ride, you're not alone on that. I have been saying this for almost two years now.
LGS is horrible and was induced, in my case, by abx.

BUT i still take them, in shot form.

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elle
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quote:
Originally posted by trueblue:
quote:



Elle

Sorry sort of Off Topic...

Elle,
What was done for the IgA deficiency?
Someone's finally thought to test me for immune complexes and IgA and IgM come up very low. I recieved no explanation but in searching found that IgA is often involved with allergic responses, etc..


Ok, back to our regualrly scheduled program...
[Big Grin] [/QB]

We have had our antibodies checked for our ability to fight different diseases that we might come into contact with. Those that we were deficeint in, we were vaccinated, quickly. Then we were retested to make certain adequate antibodies were present.

Go To:
www.primaryimmune.org/pubs/pubs.htm

Download these 2 pdf files to learn about IgG, IgM, IgA
deficeinces - these were the documents given to us when we first visited AI Dupont.

Common Variable Immunodeficeincy
Selective IgA Deficiency,


Elle

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When I feel blue . . . . . . its time to take another breath

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trueblue
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Thank you, elle! I'm off to read them right now.


BTW, I've been meaning to tell you for a long time I love your signature. [Smile]

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more truth and more innovation

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elle
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quote:
Originally posted by trueblue:



BTW, I've been meaning to tell you for a long time I love your signature. [Smile]

Thanks . . Keep on breathing . . better days are coming [Smile]

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When I feel blue . . . . . . its time to take another breath

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