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» LymeNet Flash » Questions and Discussion » Medical Questions » New California Borrelia!!!

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Author Topic: New California Borrelia!!!
CaliforniaLyme
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Borrelia californiensis
Taxonomy ID: 373543
Rank: species
Genetic code: Translation table 11 (Bacterial and Plant Plastid)
Other names:

synonym: 'Borrelia californiensis'

Lineage( full )
cellular organisms; Bacteria; Spirochaetes; Spirochaetes (class); Spirochaetales; Spirochaetaceae; Borrelia; Borrelia burgdorferi group
Entrez records
Database name Direct links
Nucleotide 17
Protein 15
Popset 6
Taxonomy 1



Comments and References:

unpublished name
This taxonomic name was not validly published at the time of submission of the corresponding sequence entry or entries.

Postic D et al. (unpublished_2006)
Postic, D., Garnier, M., and Baranton, G. "Multi locus sequence analysis of atypical Borrelia burgdorferi sensu lato isolates. Description of Borrelia californiensis sp. nov., and genomospecies 1 and 2." Unpublished (as of 24 February 2006)

--------------------
There is no wealth but life.
-John Ruskin

All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer

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treepatrol
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I added it to -More Tick Disease & Other Bugs
Now For something Completely Different Genus's -in Newbie links
Now For something Completely Different Genus's Link

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Do unto others as you would have them do unto you.
Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.

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Truthfinder
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Oh, my - a new kid on the block. Or maybe just an old kid that now has a name.

I assume they isolated this new critter from a tick, rather than human/animal blood.

I hope more info will pop up.

Tracy

--------------------
Tracy
.... Prayers for the Lyme Community - every day at 6 p.m. Pacific Time and 9 p.m. Eastern Time just take a few moments to say a prayer wherever you are.

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CaliforniaLyme
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Interestingly, there is already a HUGE mud dwelling spirochete entitiled spirochete bajacaliforniensis!!! (NO kidding!!!) But this is a new borrelia!!!!!!!!!!!! Which means it could be infecting lotso seronegative Lymies in CA*)!*!!!!
*******************
Here's the non-borrelia for clarification- very similar name!!!
*****************

1: Arch Microbiol. 1985;142:317-25. Links

Spirochaeta bajacaliforniensis sp. n. from a microbial mat community at Laguna Figueroa, Baja California Norte, Mexico.

Fracek SP Jr, Stolz JF.
Department of Biology, Boston University, MA 02215, USA.

A new anaerobic spirochete was isolated from anaerobic muds beneath the laminated sediment in the evaporite flat at Laguna Figueroa, Baja California Norte, Mexico. The organism is a member of the stratified microbial community involved in the deposition of the laminated sediments in the lagoon. The size of the spirochete is 0.3 by 30 micrometers, with a wave amplitude of 0.5 micrometer and a wavelength of 1.25 micrometers. The periplasmic flagella have a 1-2-1 arrangement. The outer membrane of the modified Gram-negative cell wall (the sheath) is irregularly crenulated and has a sillon. The growth medium contained yeast extract, trypticase, cellobiose, sodium thioglycolate and at least 20% natural seawater. Chemically defined artificial seawater media did not support growth. Optimal growth occurred with a seawater concentration of 80% at 36 degrees C and a pH of 7.5. Glucose was fermented to acetate, ethanol, carbon dioxide and hydrogen. The guanine + cytosine content of the DNA was 50 mol %. The spirochete body reacts positively to antibodies raised against eukaryotic brain tubulin protein. On the basis of its free-living anaerobic habitat, its unique morphological and physiological characteristics and G+C ratio, it is proposed that this isolated be considered a new species and names Spirochaeta bajacaliforniensis.

PMID: 11542001 [PubMed - indexed for MEDLINE]

--------------------
There is no wealth but life.
-John Ruskin

All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer

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lou
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Any more info on where the californiensis sp was found? Seems to me there might be a difference in pathogenicity between free-living (in baja mud) versus those living inside higher forms of life, like people and ticks.

But it was interesting that the baja sp was anaerobic.

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treepatrol
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Another example: Spirochaeta bajacaliforniensis thrives without oxygen in the sulfurous muds of Baja California. All Spirochaeta are resistant to high sulfide concentrations. Hot, salty mud stinking of sulfur seems to be a good home for these creatures.SOUNDS LIKE IT CAME RIGHT FROM HELL

Spirochaeta bajacaliforniensis sp. n. from a microbial mat community at Laguna Figueroa, Baja California Norte, Mexico
Journal Archives of Microbiology
Publisher Springer Berlin / Heidelberg
ISSN 0302-8933 (Print) 1432-072X (Online)
Subject Biomedical and Life Sciences
Issue Volume 142, Number 4 / September, 1985
Category Original Papers
DOI 10.1007/BF00491897


Pages 317-325
SpringerLink Date Sunday, December 12, 2004
S. P. Fracek Jr.1, 2 and J. F. Stolz1, 3

(1) Department of Biology, Boston University, 02215 Boston, MA, USA
(2) Present address: Section of Receptor Biochemistry, N.I.N.C.D.S., Bld. 36, Rm 2002, N.I.H., 20205 Bethesda, MD, USA
(3) Present address: Jet Propulsion Laboratory, California Institute of Technology, 125-112, 4800 Oak Grove Dr., 91109 Pasadena, CA, USA

Received: 9 April 1984 Accepted: 3 May 1985

Abstract A new anaerobic spirochete was isolated from anaerobic muds beneath the laminated sediment in the evaporite flat at Laguna Figueroa, Baja California Norte, Mexico. The organism is a member of the stratified microbial community involved in the deposition of the laminated sediments in the lagoon. The size of the spirochete is 0.3 by 30 m, with a wave amplitude of 0.5 m and a wavelength of 1.25 m. The periplasmic flagella have a 1-2-1 arrangement.

The outer membrane of the modified Gramnegative cell wall (the sheath) is irregularly crenulated and has a sillon. The growth medium contained yeast extract, trypticase, cellobiose, sodium thioglycolate and at least 20% natural seawater.

Chemically defined artificial seawater media did not support growth. Optimal growth occurred with a seawater concentration of 80% at 36 C and a pH of 7.5. Glucose was fermented to acetate, ethanol, carbon dioxide and hydrogen. The guanine+cytosine content of the DNA was 50 mol %. the spirochete body reacts positively to antibodies raised against eukaryotic brain tubulin protein. On the basis of its free-living anaerobic habitat, its unique morphological and physiological characteristics and G+C ratio, it is proposed that this isolate be considered a new species and named Spirochaeta bajacaliforniensis.


Key words Spirochaeta bajacaliforniensis - Spirochete - Laguna Figueroa - Microbial mats - prePhanerozoic Aeon - Tubulin-like protein

SPRINGER LINK

--------------------
Do unto others as you would have them do unto you.
Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.

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CaliforniaLyme
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I wrote Monique Garnier- she and Daniele Postic are in France and Baranton I believe in Austria!!! But they have all done work with Dr. Lane from Berkeley (entomologist not LLMD so don't get mad I wrote his name!!!))!!!

Hopefully she will write back*)*!)!)
I'll let you guys know-
Best wishes,
Sarah

--------------------
There is no wealth but life.
-John Ruskin

All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer

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James H
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They don't mention anything about it being pathogenic to humans or animals.

There are alot of different spirochetes that live in swampy water etc. that are no threat to humans. This one lives way down in the layers of mud.

... Oh. I see there are two different ones being discussed here.

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nellypointis
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quote:
Originally posted by CaliforniaLyme:
I wrote Monique Garnier- she and Daniele Postic are in France and Baranton I believe in Austria!!!

Sarah,

They are all in France,Baranton is the head of the Unit des Spirochtes at the Pasteur Institute in Paris. I heard he and D.Postic are about to retire. He's definitely NOT on our side of the fence, but he mightbe of some use to you nevertheless re the IDing of this particular spiro.

Nelly

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brentb
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Anyone have a family tree for the little fellers? I doubt we can find the granddaddy borrelia. Once again blown away by the complexity of this organism. To adapt to whatever the environment throws at it is a salute to evolution. Thanx for the post!
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brentb
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quote:
Originally posted by treepatrol:
For something Completely Different Genus's Link[/URL]

Good god did you compile this! [bow] What does the risk group category mean?

SOUNDS LIKE IT CAME RIGHT FROM HELL LMAO [Big Grin]

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Robin123
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Hm... jus' thinking about this new/not-so-new kid on the block...I've read about life starting deep in the ocean by sulfuric vents in the ocean floor; no oxygen there.

Does anyone know whether spirochetes can be found in water? Just starting to think this might be a really old organism with a connection to sulfur/no oxygen environment...

If it comes from the oldest time of life, then indeed it is our nemesis, since it thrives in a nonoxygenated environment.

My understanding is that the spirochete infection makes us anaerobic rather than the other way around -- ie, I haven't read that we become anaerobic and then that invites the spirochete to do its dirty work in us.

But that would be an interesting theory -- if there was any way we became less oxygenated, thereby setting up a terrain for the spirochete to settle in.

This is only creative pondering -- if anyone has any biology research knowledge, I'd be interested in learning about it.

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treepatrol
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quote:
Originally posted by brentb:
quote:
Originally posted by treepatrol:
For something Completely Different Genus's Link[/URL]

Good god did you compile this! [bow] What does the risk group category mean?

SOUNDS LIKE IT CAME RIGHT FROM HELL LMAO [Big Grin]

YEP [Big Grin]

--------------------
Do unto others as you would have them do unto you.
Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.

Newbie Links

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CaliforniaLyme
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Nelly- thank you!!!!

Robin- yes, leptospirosis- a spirochete- prefers liquid and is spread easily in liquid- hence a lot of California sea lions are infected right now- and dairy farmers are at high risk for it as well- because they can be spread through milk-
but last year in India polluted water after a flood had a HUGE leptospirosis outbreak as a conseuqnce!!!

I dated a ocean biologist, (where is my brain, I just woke up!) a MARINE biologist VERY VERY briefly who specialized in those ocean vents- interesting subject!!!

Garniers addy was invalid but I found one for Postic and wrote her- hope she writes back!!!

--------------------
There is no wealth but life.
-John Ruskin

All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer

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Areneli
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There are many Borrelia in nature.
Only a few types are pathogenic for men.
Most do their business somewhere else.

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CaliforniaLyme
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No, I don't believe so!! Anything is possible!!!
Wouldn't that be extraordinary>? We don't really know that either are non-path actually- have you read those books re history of DNA evolution- things chnage much more quickly than formerly believed- and go in and out of the ocean- and I imagine if a being can evolve to go in and out of the ocean in and out of humans is not so hard to imagine!!!!!!!!!!!


And leptospiroris historically has affected soldiers in wartime in outbreaks and was known as MUD FEVER!!!!!!!! Because it was spread through mud!!!!!!!!!!!!!!!!!!!!!!!!

And this thread is about a borrelia that is very likely to be pathogenic to humans!!! I shoudln't have brought up the similarly named most likely non-path one because I think it confused the thread- sorry guys, just thought it was neat we have both a bajacaliforniensis AND a plain old borrelia californiensis now!!!!!

But lepto is a mud dweller like baja- and infects humans-!!!!!!!!!

I am of the mind that there are hundreds of undiscovered creatures in us- *)!!

--------------------
There is no wealth but life.
-John Ruskin

All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer

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CaliforniaLyme
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ANd we get these IDEAS about WHERE things are that are sometimes just plain silly- like oral treponemas- they just cause gum problems, right>?
So who KNOWS what is in us!!!! Oh the wonder*)!
*************************************************
1: Oral Microbiol Immunol. 2002 Apr;17113-8.

Molecular and immunological evidence of oral Treponema in the human
brain and their association with Alzheimer's disease.


Riviere GR, Riviere KH, Smith KS.


Department of Pediatric Dentistry, School of Dentistry, Oregon Health
and Sciences University, Portland, OR 97201-3097, USA.


The purpose of this investigation was to use molecular and immunological techniques to determine whether oral Treponema infected
the human brain.

Pieces of frontal lobe cortex from 34 subjects were analyzed with species-specific PCR and monoclonal antibodies.

PCR detected Treponema in 14/16 Alzheimer's disease and 4/18 non-AD donors, and AD specimens had more Treponema species than
controls. PCR also detected Treponema in trigeminal ganglia from three AD and two control donors.

Cortex from 15/16 AD subjects and 6/18 controls contained Treponema pectinovorum and/or Treponema socranskii species-specific antigens. T. pectinovorum and/or T. socranskii antigens were also found in trigeminal ganglia and pons from four embalmed cadavers, and 2/4 cadavers also had Treponema in the hippocampus.

These findings suggest that oral Treponema may infect the brain via branches of the trigeminal nerve.


PMID: 11929559

--------------------
There is no wealth but life.
-John Ruskin

All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer

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Areneli
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***Is there reason to believe that a non-pathogenic bacteria (to humans) will never mutate to a pathogenic one?***

Very unlikely

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