I am not doing very well on it but it is early days, only 5 weeks so far.

Many thanks

That is very encouraging, can you remember when you first started to notice improvements on the Biaxin plus Plaquenil? Did it take a very long time or did you feel a bit better say after a couple of months.

I had read about switching back to Doxy after saying doing the protocol for 6 months. Did you do the Doxy on its own? Sorry for all the questions.

Plaquenil caused a huge problem, because it can make a person with babesia feel a little better without actually curing the illness. If you agree with the theory that the presence of babesia blocks the action of Lyme medication, then plaquenil is a drug that can be used to keep people coming back for years by offering minor relief, without eradicating a curable illness.

If you Google plaquenil and artemisinin, you can get info on how the World Health Organization recently dropped plaquenil as a viable malaria treatment, because it bred too much resistance.

My Lyme recovery changed completely after starting on full co-infection treatment. I have been sick for almost five years, and abruptly started seeing improvement after switching to more powerful drugs and drug combinations about six months ago.

But in order to do this, I had to change doctors. My last one went ballistic when I requested mepron for babesia, and started getting better right away. How would I ever learn the spiritual lessons of patience and voluntary poverty if I wasn't disabled for years and years?

What do you mean that "you are not doing very well on it"?

Anyone experiences herxes with this regimine?

Biaxin and Plaquenil were among the most beneficial combos that I've done. I felt better on them and was more functional at university.

I will add, though, that I came to that combo after having done several other abx first: doxy (prescribed by a non LLMD), and tetra. Sometimes I think that what abx you have already taken have an effect on how something works. (Please note, though, I am not an LLMD! )

Also, we are all so different. The way that the bacteria affects each of us is different, and there are more than 300 strains of the Lyme bacteria itself. I have found it to be a kind of trial and error process of what abx work best. I don't think a Dr. knows what strains we have until he/she starts trying different abx.

I generally go in blocks of 3 months to see if I feel improvement. But ``improvement'' can be misleading, because, as we all find out, Lyme is a cyclical recovery, and there will be periods of actually feeling worse before feeling better. I don't mean to be discouraging, though!! When you have these bad times, you know you are on the way to improving.

My Lyme went misdiagnosed and untreated for more than 5 years; so I have found improvement over long periods of time. (I'll notice a slight change in 3-4 months; and I'll look back at the year before and see that I'm able to do more).

There was a huge change in my cognitive functioning after 4 months on tetra. Even though tetra didn't do a whole lot for my physically, it did clear a lot of mental fog, and after 4 months on it I was able to take my Ph.D. Orals. (A miracle. LOL).

We are all totally different. My advice would be to stick with something for 3 months. Some other folks more knowledgeable than I can explain the life cycle of the cells so that 3 months is a time when you know you've hit the bacteria at least once. (Please chime in, people who know more than I do!)

And, of course, make sure you are tested for co-infections and discuss that treatment, too, if necessary.

I hope that you feel better soon. I know there are many folks here who truly understand. One being me.

I don't think people knew what you meant by the protocol of Professor Donta.

I was on Biaxin and Plaquenil for about 3 months last summer. I know I had more leg pain the entire time on Biaxin. I don't know if it helped, but I do know I had faster progress when I switched to Levaquin.

I am taking 1000mg Erthryomycin with 400 mg Plaquenil since 15 March. For the first 10 days I felt really good but then my health started to go backwards.

My main problems have been inability to walk very far before neuro symptoms kick in, periods of intense pain especially in neck and shoulders. It feels like there is inflammation in my body from time to time but this has improved since taking 1 tablespoon of Cod Liver Oil daily and sitting in the sun a little. I don't have any pain at the moment, just bad fatigue and inability to walk much.

Generally after 5 weeks I haven't been able to see any improvements but would say I am slightly worse. Also I caught a nasty virus last week that hit my gut very badly, no diahorrea but horrible pains together with absolute exhaustion and fatigue. Today was the first morning I felt normal after 6 days but still my energy ran out by 2 pm this afternoon and when I went for a short walk all the neuro symptoms were back together with a panicky feeling.

It has been pointed out to me that it is very early days with this specific combo but I would like to see some improvements.

Previously I have done 6 months Doxy plus 3 months pulsed Tinidazole. I had very good improvements on the Doxy but after a time it just stopped working and I hit a plateau I think.

I understand I will have to switch back to a different abx for another 3 months and then start on Biaxin and Plaquenil for another 6 months.

It would be good to hear of other people's progress with Biaxin and Plaquenil. Is Dr Donta well regarded in the US?

Thanks again