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» LymeNet Flash » Questions and Discussion » Medical Questions » Ideas - Reduced Glutathoine, sublingual form

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Author Topic: Ideas - Reduced Glutathoine, sublingual form
RECIPEGIRL
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Hi Guys,

Anybody know of the best Reduced Glutathione you can take sublingually?


I read that someone here opens one plain Twinlab Glutathione 100 mg. capsule ($12 bottle) and empties it under the tongue on bad days.


I tried it when I woke up feeling bad like I had ``Lyme flu'' & I felt better fast. (Normally I would take 3 Motrin tablets. ) Gosh, this makes me feel human again even after 20 months of ABX.


Anyway, I was able to get going at home (can't work). I'm really slow in the morning-------that's an understatement.


I plan to research & see if Glutathione supplements taken sublingually go to the brain even a little because I have neuro lyme.


Don't know if it will help others, but it helped me.


After taking the sublingual Glutathione, I went ahead and swallowed a NAC capsule away from ABX with lots of water (which converts to glutathione in the body) on an empty stomach which further helped me that day.


It strengthens your entire body & detoxifies the liver. [The NAC capsule was by Biochem (NAC) N-Acetyl Cysteine 750 mg. 30 capsules made by CountryLife. I always have these on hand.]

I also take NAC (sulphur) as it strengthens my voice. I first learned about this in a book by Hanna Kroeger, Vitamin - Mineral Locator.


I know others disagree about taking NAC because it pulls out heavy metals, but I've taken NAC since the early 90s & it has been a lifesaver for me.


Actually, that was long before I had my mercury amalgams removed. I really can only say what works for me.

The next thing I want to try is the real stuff: It's called ``Reduced Glutathione'' It's over the counter & you can order it from a compounding pharmacist.


Naturally, you can purchase from one nearby & avoid shipping charges.

So far, my bit of research states that Reduced Glutathione is metabolically active and must contain riboflavin, niacinamide, selenium, lipoic acid and glutathione reductase as co-factors to generate reduced glutathione.

I found Jarrow Formulas makes a Reduced Glutathione 500 mg, 60 capsules for $34 on the web. It states that it's pharmaceutical grade, but who knows for sure. I've always heard Jarrow is good.

Also, Source Naturals makes a ``Reduced Glutathione Sublingual Complex plus Molybdenum,'' 50 mg., 100 Tablets.. Directions state use 3 tablets daily.


My son away at school might be willing to take Source Natural's because it's so convenient; plus, I've always loved anything by Source Naturals.

Here's the info on the expensive Reduced Glutathione from a compounding pharmacy. I'd just use it on bad days or when in head pain. It might be worth it if I can make it last for a couple of months.

Oral Reduced Glutathione - OTC (no RX needed)
2 fluid oz. bottle $50.00
1 1/2 tsp. 2 X daily


(I would take it sublingually & hold under tongue for a few minutes as stomach acid destroys glutathione.)


Can use up to 8 bottles per month ($300--yikes!) & S&H.
(No overnight shipping required)


I have also done the Glutathione & ATP injections once weekly supplied by my retired physician. Those had to be injected in the thigh & the needle was huge.


Another compounding pharmacy said to use the tiny insulin syringe. However, my LLMD said his injections were ready to go at $10 an injection so that's what I did.

Here's where I got the info & prices on reduced glutathione:

WELLNESS PHARMACY
2800 South 18th St.
Birmingham, AL 35209
(800) 227-2627

I found this information at:

http://www.chronicfatiguesupport.com/library/showarticle.cfm/ID/6054


For sinus problems: Need RX
Reduced Glutathione Nasal Spray
100 mg/ml for 1 month
Take 2 sprays 4 X daily
1 month = 50 ml $60.00

Overnight Shipping Required $27.50
From compounding pharmacy.


For Lungs: Need Prescription for both Glutathione and for the nebulizer machine (breathing treatment machine used for COPD & asthma treatments).


My son has LD & asthma so I was interested in this.


Reduced Glutathione Solution: 3 ml vial
100 mg/lml for nebulizer.
$4 per nebulizer vial &
Overnight Shipping Required $27.00
From Compounding Pharmacy


Best Glutathione:
If I could afford this weekly:
Glutathione IVs - from alternative doctor

For the record: I don't take NAC daily. I don't take NAC with minerals------feel like it would pull them out. I take NAC away from ABX. On an ABX holiday, I'd take NAC with Vitamin C & Vitamin B6 to activate .

Anyway, hope this helps someone. This sub-lingual Glutathione just may get me through Christmas.

Take Care,
Jan


P.S. Additional links for background reading on this subject are in my reply to Lisa below.

[This message has been edited by RECIPEGIRL (edited 19 December 2004).]


Posts: 602 | From Burleson, Texas, USA | Registered: Jul 2004  |  IP: Logged | Report this post to a Moderator
WildCondor
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You can get sublingual glutathione compounded.I did it and took it for a month. Honestly it didnt do anything that I noticed, and it tasted SOOO bad that I had a hard time to keep from vomiting it every time. Its got this sharp bit to it that triggers the drool reflex and tastes so bad and wont go away for hours and then you start to smell like it. Maybe they all arent like that, but mine was and I didnt refill it.!

------------------
Lyme Disease Help
http://www.wildcondor.com


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RECIPEGIRL
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WildCondor,

Thanks for the heads up. When I called the pharmacy they didn't tell me that it tastes bad. I will be sure & ask them though.

I suppose it's the sulphur in it------that would do it.

I'm just a huge responder to glutathione, so I do want to try some less pricey ones I listed first.

Thanks,
Jan


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troutscout
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i respond to NOW brand reduced glatathione sublingually.

Trout

PS>>>Have you tried "Chem-Defense"?
I forget who makes it...sublingual..it has a mixture of moly and the other things critical for it to work.
I used this when I was a severe MCS patient also.


Posts: 5262 | From North East Iowa | Registered: Sep 2002  |  IP: Logged | Report this post to a Moderator
RECIPEGIRL
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Troutscout,

Thanks for the helpful input. Eventually I'll probably try NOW since you say it works. I'll be sure & check it out.

I just ran across that CHEM-DEFENSE product earlier today and it's called:

Chem-Defense by Source Naturals

(It looks like it has the exact ingredients as the Reduced Glutathione by Source Naturals noted in my post. Perhaps one is renamed------ don't know.)

Thanks,
Jan


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Foggy
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I do weekly 2000mgs Glutathione IV drips.
Posts: 2451 | From Lyme Central | Registered: Aug 2001  |  IP: Logged | Report this post to a Moderator
nan
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I have had the IV glut. in the doctor's office. Amazing stuff. I had relief from pain instantly and a great feeling of well-being.

Cannot afford to have the IV's but doc ordered me the glutathione nasal spray
from Wellness. (1-800-227-2627) He claimed it was the next best thing to the IV. Directions are to use it four x a day, but I have saved it for days when I really need it.

It is expensive ($100 per month)and must be prescribed.
Amazing stuff! Would like to get the sublingual glut and try it.

Label on my bottle says: Glutathione 100MG/ML Nasal Spray.


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Lyma Bean
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I have been doing TwinLabs Mega glutathione,sublingually, for some time now. I really didn't think it was doing that much until I ran out and it took four weeks to get it shipped to me . I experienced the worst pain that I've ever had with this DD. I will never be without it again.

I get mine from www.discountblvd.com
They have the best price I've found


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nan
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Hi Lyma Bean,

Description did not call it sublingual?

Please explain for my lame brain?

Thanks,...nan


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Lyma Bean
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Hi Nan!

From one lyme brain to another ....they are capsules that you open and dump the contents under your tongue. Not especially tasty but you get used to it after a while.


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RECIPEGIRL
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Foggy, thanks for the info. I bet the IV really helps you alot.


Nan, thanks ---- It's very encouraging to hear the nasal spray works & that you got it from Wellness pharmacy. Didn't know it was as good as the IV. I just believe anything that goes in the nose is bound to go to the brain------don't know for sure.


I return to the LL/FNP this month, so I will ask for a nasal spray RX. Don't think I could tolerate the taste of the Wellness sublingual liquid.


Lyma Bean, thanks----I didn't know Twinlab made a Mega glutathione. Too cool. Thanks for the web site & good price. I'll check it out. Glad to know it helps you. The Twinlab has already helped me immensely.


Thanks everybody. Ya'll never cease to amaze me. I was just doing an experiment with the Twinlab Glutathione & didn't really know what I was doing.

Bye,
Jan


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nan
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RecipeGirl,

Actually, the nasal spray doesn't do the job that the IV stuff did. But I do feel it is helping! If I could afford it, I'd go the IV route.

Lyma....thank you for the clarification. Now my lyme lame brain gets it!

nan


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lla2
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what exactly is the mechanism behind this? why does it work? is it an antihistimine? I 'm not understanding why something would make us feel so much better...

Id like to try it, but with all my other meds and alternative stuff is it safe ? I mean ok to take iwht thyroid problems etc...adn clonazapam at night , blah blah blah...along with abx?

thanks, if so , then this sounds like a lifesave for those days I have trouble going to work...

Lisa


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RECIPEGIRL
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Hi Lisa,

Maybe some of the scientists on the board can give you the best reason why sublingual L-Glutathione (GSH) works so fast.


This is only what I've read.


L-Glutathione is an amino acid made up of cysteine, glycine and glutamic acid. Stomach acid destroys glutathione so can't take it orally.


That's why folks take the amino acid, NAC (N-acetyl cysteine) a sulphur amino acid
orally which is the precursor to glutathione. Stomach acid does not destroy NAC.


For new readers, never take L-cysteine by itself because it can raise your homocysteine levels; bad for the heart & blood vessels.


L-Cysteine alone acts like a Brillo pad tearing & inflamming the inside of the blood vessels. I would never take plain
L-cysteine.


Back to GSH.
It is a powerful detoxifier. That's the understatement of the year!


IMHO, GSH works fast because your taking it sublingually which, as I'm sure you know, is absorbed immediately into the blood stream which bypasses the first pass through the liver.


Also, amino acids, generally speaking, tend to work fast-----some within hours. That's why I like them. It's not like building up your mineral reserves which take can take a while.


GSH is a neurotransmitter which affects the nerves/brain. This is probably key for me because my nerves have been fried after years without a diagnosis.


Because GSH contains sulphur in the form of cysteine, it is the sulphur that strengthens the overall body.


Especially in chronic illness oral NAC is recommended. It then converts to glutathione.


Here's more of my amateur opinion on this:


Even though glutathione is an antioxidant, I don't think I'm getting such a big dose of GSH when I take a Twinlab 100 mg sublingually to adversely affect ABX. Twinlab is not even the "reduced" kind & it still helps me.


I'm going to use my Twinlab GSH until it runs out, but am very excited about trying the "reduced glutathione" which is biologically more active in the body.


If I were going to take my oral NAC of 750 mg, then I take it far away from ABX. Don't know if the 2-hour rule about taking supplements away from ABX applies to GSH.


Or, if you take an ABX holiday, that'd be a great time to up you GSH/NAC levels.


As far as GSH being contraindicated with thyroid----


I've always heard it's a good idea to take thyroid away from anything else. But that's strictly up to your physician & what works best for you.

Folks who take Glutathione IV could probably shed more light about timing it with ABX.

Glutathione Links for background reading:


Product Picture & description: http://www.iherb.com/glutathione1.html

Reader friendly: http://www.chronicfatiguesupport.com/library/showarticle.cfm/ID/6054

Reader friendly: http://www.woodmed.com/Glutathione%202002.htm


More technical - Glutathione Monograph http://www.findarticles.com/p/articles/mi_m0FDN/is_6_6/ai_81761456

I've mentioned this in my first post, but want to repeat for new readers:


L-Glutathione or NAC (N-acetyl cysteine) detoxifies heavy metals: mercury, lead, arsenic and cadmium.

It is a controversial issue, but some believe
NAC merely chelates heavy metals & redeposits them in the body causing further damage.

I've been taking NAC intermittently since the early 90s & it's helped me beyond belief. I just do what works for me. I've got to have some life.


Everyone has to evaluate the pros & cons of anything & make his own decision.


Plus, some people respond to L-glutathione & some don't.

Bye,
Jan

[This message has been edited by RECIPEGIRL (edited 19 December 2004).]


Posts: 602 | From Burleson, Texas, USA | Registered: Jul 2004  |  IP: Logged | Report this post to a Moderator
Happy Camper
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I would like to jump in here. I recently started L-glutathione.

I am using the kind where you mix it with another ointment and rub it into your skin.

My LLMD had recommended IV glutathione for me months ago but it was not feasible at the time.

I came back to this web site to do some research on the subject.

Thanks for the info.

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Carol in PA
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Here is the product I bought, after reading about the sublingual form of glutathione.

Reduced Glutathione Sublingual Complex, Source Naturals, 50 mg, 100 Tablets
SRP: $18.50
iHerb Price: $10.55
http://store.yahoo.com/iherb/glutathione1.html

I take this right before I lie down to meditate. It has a pleasant orange flavor.
I also take a sublingual form of Vitamin B12, methylcobalamine.
http://www.iherb.com/methylsn5.html


From other things I've read, it seems that it might work better to take the precursers to glutathione, so that your body can make it itself.

Off the top of my head, I think the precursers are acetyl L Carnitine and NAC (N acetyl cysteine).
I take these too, in an effort to "cover all the bases."

Carol

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duramater
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here's a query: why is the abbreviation for glutathione GSH??? how did that S sneak in there? and why did the H get elevated to the level of accronym importance?
Posts: 689 | From western MA (we say buttER and pizzA) | Registered: Nov 2004  |  IP: Logged | Report this post to a Moderator
   

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