posted
Thanks to Riversinger for directing me to this doc's website.
This article is very relevant to hubby's situation and probably describes others with severe neurolyme symptoms as well. Through trial and error and many docs hubby had actually pretty much arrived at the suggested supplement list over the last 5 years.
However due to financial constraints we have substantially reduced the number and doses of supplements he was taking for the last 8 or 9 months. Do feel this has directly impacted his treatment and slowed down recovery.
Anyway, the article makes sense of what had been a hodgepodge of ideas in my mind. The thing the article does not address is how to measure the actual amount of neurological inflammation. I know there are many others who have run into this issue - you have ``normal'' neuro exams except for possibly a few brain lesions that are considered irrelevant by most docs yet you have severe neuro impairments - either muscular or movement or cognitively related or a combination.
Neurological Inflammation: An Approach to Reversing the Process
Introduction
I believe that knowledge is power, and the more you know the more control you have over your condition. One of my goals is to share my knowledge, observations and experience so that others might have the tools they need to aid in their own healing process.
Individuals can then apply this knowledge to first halt the progression of neurological inflammation and then begin the journey of reversing the symptoms. The standards that I set for improvement are high. I am not content that an individual is simply doing better than they were before working with me, I expect that to occur.
I have not yet reached a ceiling with any of the types of neurological cases that I work with including ALS, SLE, Parkinson's, MS, Alzheimer's, Myasthenia gravis and autism.
What I mean by this is that the people I work with continue to improve without reaching a plateau. I work with an individual who has a form of ALS. Over the past 2 years he has continued to reverse his disease and to progress steadily. This is what I expect to see from all of the individuals that I work with.
The Program
The program that we use at Holistic Health Consultants has three basic phases: First, I find that it is critical to remove excitotoxin triggers from the diet. This simply involves reading labels and closely monitoring food and supplement intake to avoid excitotoxins.
Excitotoxins are neurotransmitters such as glutamate or aspartate that can excite the nerves to death when their levels are not regulated properly. Foods or supplements that contain excitotoxins include MSG (monosodium glutamate), glutamic acid, glutamine, nutrasweet, aspartate, aspartame, and cysteine. Mercury and aluminum can also serve to trigger glutamate release.
Next, it is important to stop the inflammatory process created by the excitotxin triggers. Excess excitotoxins cause an imbalance in the flow of calcium, which leads to activation of a complex inflammatory cascade, release of inflammatory mediators and ultimately causes the death of neurons. Halting this inflammatory cascade is achieved with a number of supplements known to mitigate inflammatory mediators.
Finally, the third stage is to repair the damage, generate new neurons, and support the liver. This is accomplished with a number of supplements, which serve as antioxidants as well as to help increase glutathione levels, restore liver function, promote nerve growth, restore vitamin K levels, decrease glutamate levels, and balance GABA levels.
The number of supplements utilized varies from approximately 5 to 50 or more, depending on the severity and the number of the imbalances in each individual. The systems or imbalances that may require supplementation include the pancreas, the intestinal tract, excessive acid production in the stomach, the liver, hormonal imbalances, thyroid, adrenals, and neurotransmitter imbalances among others. This may seem like a lot of supplements, and in some cases it is.
However, what we are attempting to accomplish is the reversal of a lifetime of accumulated damage. Nerve damage is a cumulative process. By the time an individual consults with me, more than 50% of their neurons may have damaged to the point that it is causing obvious neurological symptoms.
It takes time and commitment in order to halt and reverse this process. How long does it take to grow a new neuron ? No one really knows. What I do know is that when I have an individual who commits to their program and stays with it, together we are able to acheive incredible results.
Excitotoxins
Glutamate is the main excitatory neurotransmitter in the body. It is essential for learning and for both short-term and long-term memory. It is also the precursor to the inhibitory neurotransmitter, GABA. GABA is a calming neurotransmitter, and is essential for speech.Problems occur if the normal process of regulation of glutamate malfunctions and if toxic levels of this excitatory neurotransmitter build up in the synaptic junctions.
The brain requires sufficient levels of oxygen and energy to remove excess glutamate. However, glutamate release leads to the release of insulin, which results in decreased glucose levels. The amount of glucose in the brain regulates the removal of excess glutamate from the synapses.
Therefore, a drop in blood glucose disrupts this removal process and allows the build up of toxic glutamate. In fact, conditions of hypoglycemia, or low calorie/starvation conditions induce the release of glutamate and reduce the ability to remove excess levels of glutamate from the brain.
This excess glutamate depletes glutathione. Glutathione is one of the most powerful antioxidants found in the body and helps to protect neurons from damage. Glutatione depletion consequently leads to the death of additional neurons.
Glutamate has six different types of receptors to which it can bind in the brain. One of these receptors, the NMDA receptors, is tied to calcium transport as its mode of action. In the case of the NMDA receptors, the release of excess glutamate triggers an inflammatory cascade that results in the death of neurons by the major influx of calcium into the nerve until it results in neural cell death.
Normal levels of calcium result in normal neuron functioning. However, excessive levels of calcium make it impossible for the neuron to rest; the neuron continues to fire without stopping, causing the release of inflammatory mediators, the release of more glutamate, thus resulting in more calcium influx.
The high intracellular levels of calcium also lead to high levels of nitric oxide and peroxynitrite, causing damage to the energy producing apparatus of the cells. Magnesium is able to modulate the calcium flow, as is zinc. However, zinc is a double-edged sword as it is also able to activate glutamate release via the non-NMDA glutamate receptors.
Although these receptors are called "glutamate receptors", any of the excitatory amino acids are able to bind to the receptors and cause excitotoxin damage. The toxic potential of these excitatory amino acids has been suggested to be proportional to their ability to excite neurons. These excitatory amino acids include glutamate, aspartate, and to a lesser extent, cysteine and homocysteine.
Glutamate and aspartate are common as food additives as well as naturally occurring components of a large number of foods. In cells, glutamate and aspartate can be synthesized from each other. The two main food additives that are sources for excitotoxins are MSG (monosodium glutamate) and aspartame (nutrasweet).
High levels of glutamate and aspartate are found naturally in protein rich foods, including very high levels in wheat gluten, and milk casein. While these amino acids are necessary for normal brain function, excess amounts of them create a wide range of bodily damage.
Body systems that have been affected by glutamate toxicity include effects on white blood cells (elevations in the levels of eosinophils,), effects on blood vessels (causing migraines and reduced regulation of blood pressure), and inhibition of the conversion of glutamate to GABA.
The sites in the brain that have been reported to be damaged by excitotoxins include the hypothalamus, the hippocampal neurons, and the Purkinje neurons, among others.
Excess levels of glutamate have been definitely implicated in a range of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, Huntington's chorea, stroke, Multiple sclerosis, and ALS. In the case of autism, irregularities related to glutamate have been observed.
Liver Health
The liver is probably one of the most important organs in the body when it comes to health. The liver is the site for carbohydrate, fat and protein metabolism, storage of vitamins and minerals, and regulatory mechanisms for blood sugar and hormone levels. Bile production, which is necessary for elimination reactions, also takes place in the liver.
In addition, and perhaps most importantly, the liver is the site for detoxification of the body. A central problem in neurological inflammation is the function and health of the liver. If the liver is healthy, it can make sufficient enzymes for the efficient detoxification of the body. The liver contains high levels of enzymes, and enzyme systems that are required for detoxification processes.
In addition to high levels of excitatory amino acids, low levels of glutathione have been associated with a number of neurodegenerative disorders. The liver contains one of the highest levels of glutathione. Glutathione is one of the most powerful antioxidants found in the body. Glutathione is essential for both the phase I and phase II detoxification systems of the liver.
Phenol-sulphotransferase (PST) is another sulfur- containing enzyme that detoxifies leftover hormones and toxic molecules, as well as food dyes and chemicals. High extracellular levels of the excitotoxin glutamate cause the extrusion of intracellular cysteine- resulting in glutathione depletion. Low levels of magnesium also result in decreased levels of glutathione, as does infection or inflammation that cause elevations in the inflammatory mediator TNF alpha.
GABA
Another issue with neurological inflammation are imbalances between glutamate and GABA. While glutamate stimulates neurotransmission and can excite the nerves to death, GABA is the calming neurotransmitter. GABA is involved in social ability, controlling anxiety, and is essential for speech.
GABA neurons damp the propagation of sounds so that a distinction can be made between the onset of a sound and background noise. (GABA is often used to help restore speech in individuals who have suffered strokes.) The amino acid taurine (another sulfur containing amino acid) is itself involved in neurotransmission, and also helps to elevate the level of GABA. Taurine levels would also be depleted under conditions of low sulfation.
Normally, excess levels of the excitotoxin glutamate can convert to GABA. There seems to be a disconnect in this process for individuals with neurological inflammation so that the excitatory neurotransmission is high and the calming neurotransmission is low, where again, one sees the need for sulfur containing proteins or amino acids in this process. The enzyme that converts glutamate into GABA is located in the pancreas.
This implicates the GI tract in the process of neurological inflammation.
GI Tract
In an ideal situation, following the digestion of food in the stomach by hydrochloric acid , the HCL is dumped into the small intestine, stimulating the release of several proteins. These include gastric inhibitory peptide (GIP), secretin, and cholecystokinin (CCK).
GIP slows the release of acid into the intestinal tract, secretin stimulates the pancreas to release bicarbonate to neutralize the acid, and CCK stimulates the gall bladder to release the bile (made by the liver) into the intestines to neutralize the acid and help digest fats. If, however, the pancreas and the liver are in a weakened state, this ideal situation will not occur.
Instead, the HCL is still dumped into the small intestine; however, these three proteins will not be released properly. This results in a situation where the intestinal tract will become more acidic due to lack of released bile, and result in an environment that is more conducive to growth of yeast, E.coli, and streptococcus, rather than normal intestinal flora.
In addition, there will be inadequate digestion of fats, consequently a decrease in absorption of fat-soluble nutrients (i.e.vitamins A, D, and K), and a sub-optimal amount of secretin and CCK to trigger communication with the brain. Decreased levels of CCK in the brain are correlated with anxiety and panic.
Similar to CCK, the hormone secretin is found in the brain as well as the GI tract. Secretin has been shown to cross the blood/brain barrier. It is postulated that secretin that crosses over into the brain as well as secretin that is released by Purkinje cells in the brain may regulate cells nearby to produce GABA.
Neuropeptide Y is another peptide that is abundant in both the brain and the GI tract. In the brain, it is involved in regulation of appetite, anxiety and blood pressure. In the GI tract, Neuropeptide Y is involved in the regulation of pancreatic secretions and gut motility. Neuropeptide Y has been reported to suppress glutamate and antagonize the effects of glutamate.
Supplementation
While I formulate and suggest a specific supplementation plan that reflects the profile of a particular individual, there are some universal generalities that apply to any neurological supplementation program.
A really good general supplement that covers the vitamins, minerals and is high in antioxidant supplements will lay the groundwork for the rest of the more specialized supplements. I do not like iron in supplements as iron can exacerbate neurological inflammation. Iron is also necessary for virulence of many bacteria, including streptococci, so limiting iron is useful in limiting bacterial infection, which could trigger additional inflammation.
Individuals should get more sulfur/glutathione into the system in as many healthy ways as possible. While glutathione cannot be taken orally, it can be taken transdermally and sublingually. Also there are a number of supplements which will boost glutathione levels, these include: milk thistle, alpha lipoic acid, N-acetyl- cysteine/vitamin C, MSM, and rosemary among others.
While glutamate (or glutamic acid or glutamine) and cysteine are precursors in the formation of glutathione, they are also excitotoxins and will trigger more inflammation in the brain; therefore it is best not to use those items directly as supplements to boost glutathione levels.
Foods/supplements that are high in sulfur include garlic, broccoli, onions, and quercetin. Reduced glutathione is reportedly the more potent form of glutathione; NADH can be used as a supplement to help recycle reduced glutathione.
If the liver is healthy it can make sufficient glutathione, which is one of the most important antioxidants in the body. The liver is also critical as it is the site of detoxification of waste products for the body. Anything that makes the liver healthier will help; this would include some of the supplements already mentioned such as milk thistle, carnitine, NAC, dandelion (also high in vitamin A), as well as SAMe and B vitamins.
Individuals should consider supplements to help to detoxify the excess glutamate in the system. These would include branched chain amino acids, pycnogenol, and grape seed extract. Magnesium is critical as it regulates the excess calcium from flowing into the nerves and killing them.
Epsom salt baths (magnesium sulfate) are useful particularly if the bathing water is high in chloride and fluoride. Chloride blocks the action of sulfur in the body. Limited amounts of zinc and calcium are fine, but too much will increase nerve damage.
Supplements that add energy (oxygen and ATP) to the brain will help it to detoxify the inflammatory reactions caused by excess glutamate and heavy metals, which trigger glutamate release. These supplements include ginkgo, vinpocetine, NADH, CoQ10 and carnitine. Carnitine actually helps to increase the energy in the mitochondria, which are the energy producing organelles inside each cell. Carnitine is also useful in repairing liver damage.
B vitamins are crucial for nerve health. They also help to form the sulfur containing amino acids. A really good B complex is important. In addition B12 can be taken sublingually so that it is not degraded in the stomach. B12 helps with energy as well as to repair nerves.
It is important to take B vitamins as a complex, as it has been shown that taking a single B vitamin will deplete the levels of the other B vitamin's and this occurs in a dose dependent fashion. For example, a central inflammatory mediator in other neurological inflammation is homocysteine. Lack of particular B's will increase the homocysteine levels in the blood.
Finally, in individuals where chronic yeast or fungal infection is evident, it is important to restore the normal functioning of the intestinal tract. Supplement with a really good source of vitamin K, agents to limit yeast formation (which occurs as a result of lack of normal flora) and digestive enzymes. Supplements that will help with digestion and yeast overgrowth include lactoferrin, digestive enzymes, and probiotics.
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
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valymemom
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Bea
Could you post the amounts hubby has been directed to take.
Posts: 1240 | From Centreville,VA | Registered: Mar 2005
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posted
Sounds well thought out and pieces of it are already being used by LLMDs I think, probably empiracally or from testing they have done. I find that I am already doing a fair amount of this on my own, or by direction of docs.
In the case of infectious agents causing the neuro inflammation, this has got to be done in the presence of something that attacks the infection too, it would seem. Not alone, in other words. Can't do this by itself and expect to cure neuro lyme when the infection is still active.
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oxygenbabe
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Yes, Bea I've been thinking about referring you to Amy Yasko's work. Go to autismanswer.com and register and browse through all the postings. That could take weeks or months for you to really absorb what she's saying. Also, get her February 2006 DVD's and watch tghem a few times.
The doctor's site you posted with GARD seemed very excessive to me. It's one thing to remove casein and gluten and another to limit all kinds of stuff including nuts and beans. Your husband could be helped perhaps, by getting genetic testing, a genetic analysis review, and understanding where he is building up excess glutamate and why.
Posts: 2276 | From united states | Registered: Jun 2004
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Hubby has had some genetic testing from Great Smokies -- has problems with both methylation and sulphation. Not sure how much more extensive the testing done by Dr Amy is, but her tests seem extremely expensive and obviously genetic testing is NOT covered by insurance.
See my other post on Lyme and Excitotoxins -- feel there are two sources of glutamate for Lymies to be aware of -- diet (under our control) and produced as direct result of using antibiotics to kill the Lyme and other tickborne diseases.
Hubby has had ongoing G.I. issues from Day 1 of his tickborne illnesses -- gastritis seen on 4 different endoscopies over the last 5 1/2 years. So for him obviously diet is a major issue -- definitely believe in the leaky gut theories. Others may not need to be so restrictive of foods, but it is certainly worth a try for hubby at this point.
Lou,
I agree. Have to supplement to repair and rebuild, but this does not kill an active infection. Do feel that supplements can mitigate damage from an active infection however -- especially COQ10 (reduces lipid peroxides and free radical damage) and Resveratrol (blocks quinolinic acid).
Valymemom,
Will try to post details of hubby's supplements in next day or two.
Bea Seibert
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
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oxygenbabe
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Bea, I've been studying Amy Yasko in depth and listened to about 20 hours of DVDs. Suffice it to say I think it would be worth it. Genova testing is good and I wish I could get that too but you cannot do this on your own and her testing is more complete. There are so many places the methylation cycle can back up and break down. It is so very complex. She has a PhD and an ND. I paid for the genetic testing myself and am awaiting results. We are discussing this in depth for months now on CFS-FMExperimental yahoo group. You might want to join that and peruse the archives. Also just spend a lot of time on autismanswer.com. The site for GARD is good in its own way but his understanding is so very rudimentary. You're on the right path now I think with Yasko.
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minoucat
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This isn't about exitotoxins, but it is about brain inflammation and is another way of looking at the range of neurotoxins:
This study talks about administering cytokines; other studies with similar outcomes were done with patients who had elevated cytokines purely as a result of infection.
The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans by Wichers M, Maes M. Department of Psychiatry and Neuropsychology, Maastricht University, 6200 MD Maastricht, The Netherlands.
Int J Neuropsychopharmacol 2002 Dec;5(4):375-88
ABSTRACT Administration of the cytokines interferon-alpha and interleukin-2 is used for the treatment of various disorders, such as hepatitis C and various forms of cancer. The most serious side-effects are symptoms associated with depression, including fatigue, increased sleepiness, irritability, loss of appetite as well as cognitive changes.
However, great differences exist in the prevalence of the development of depressive symptoms across studies. Differences in doses and duration of therapy may be sources of variation as well as individual differences of patients, such as a history of psychiatric illness.
In addition, sensitization effects may contribute to differential responses of patients to the administration of cytokines. In animals administration of pro-inflammatory cytokines induces a pattern of behavioural alterations called 'sickness behaviour' which resembles the vegetative symptoms of depression in humans.
Changes in serotonin (5-HT) receptors and in levels of 5-HT and its precursor tryptophan in depressed people support a role for 5-HT in the development of depression. In addition, evidence exists for a dysregulation of the noradrenergic system and a hyperactive hypothalamic-pituitary-adrenal (HPA) axis in depression.
Some mechanisms exist which make it possible for cytokines to cross the blood-brain barrier. Pro-inflammatory cytokines such as IL-1beta, IFN-alpha, IFN-gamma and TNF-alpha affect the 5-HT metabolism directly and/or indirectly by stimulating the enzyme indoleamine 2,3-dioxygenase which leads to a peripheral depletion of tryptophan.
IL-1, IL-2 and TNF-alpha influence noradrenergic activity and IL-1, IL-6 and TNF-alpha are found to be potent stimulators of the HPA axis.
Altogether, administration of cytokines may induce alterations in the brain resembling those found in depressed patients, which leads to the hypothesis that cytokines induce depression by their influence on the 5-HT, noradrenergic and HPA system
-------------------- ********************* RECIDITE, PLEBES! Gero rem imperialem! (Stand aside plebians! I am on imperial business.)
posted
so I'm curious...I've been taking L-Glutamine for my GI tract...is this a bad thing? It was recommended to me but after reading this I don't know if it falls into the bad area.
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5dana8
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Just wanted to say that the whey protien drink that I drink & I know alot of other people are using has 2,299 units of L-glutiamine powder in their formula.
If it is mixed in with other amino acid protiens do you think it negates the bad effect of glutimine?
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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Glutamine may or may not be a problem -- in my opinion it is much more likely to be a problem if you have gastritis. Before Lyme hubby took this and it helped his G.I. heal -- since Lyme he can't take it.
Dana,
If you are using the whey protein powder as a meal replacement you may not be getting any more glutamine than in a normal diet. If you are simply trying to increase your protein intake then you may be getting excess glutamine.
You can't eliminate 100% of the glutamine from diet unless you eliminate all protein. Some people obviously will be more sensitive to glutamate than others.
According to what I have read a concentrated supplement would be absorbed within an hour and normal intake from food could take 5 or 6 hours to affect a person.
If you have problems with Aspartame or MSG then you would be more likely to have problems with glutamine supplements as well in my opinion. Don't think you would react to just one of the neurotoxins and not the others.
Aniek,
Hubby takes SAM-e, B-12 shots, B complex and folinic acid (activated form of folic acid. His homocysteine was 6 the last time he tested it so obviously the supplements are working. It took a while to experiment with doses to find what seemed to be the best combo of supplements and the correct doses for him.
Bea Seibert
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
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posted
I have chronic gastritis...I was told Glutamine would help heal it...its a real pain with so many conflicting things I'm reading to know what to do.
Posts: 594 | From NJ/NY | Registered: Jun 2006
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How many Lymies have problems with 5-HT (serotonin), noradrenergic (adrenal -- NMH or POTS), or HPA (Hypothalamic Pituitary Axis -- hormones -- includes everything from insulin to thyroid to growth hormone)?
Don't know many Lymies that don't have problems in at least one of these areas. Just another indicator that Lyme is infectious in nature if anyone had any doubts.
Bea Seibert
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
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5dana8
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posted
Thanks bea
for the additionl information. You are very helpful
Blessings
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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riversinger
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Bea, as oxygenbabe has said, I think you would find it worth looking into Yasko's information more thoroughly. I haven't done the genetic testing yet ($$$), but I have sent off for some of the other tests that I can get insurance to cover.
Yasko tracks treatment by using Urine Amino Acids, Urine Toxic Metals, Urine Essential Metals, Organic Acid Tests, and Comprehensive Digestive Stool Analysis.
Some issues will be indicated in results in these tests, and she adjusts supplementation depending on what is showing up.
I think you may want to look into what she has to say about ammonia issues, which can be genetic. She sees high ammonia as causing tremors and seizures.
Unfortunately, you have to do a lot of work to understand the complexity of her program. The good news is that you are capable of it. Check out her autism website, where people are actively involved in the program, including a grwoing group of adults.
One of the things I find exciting, is Yasko believes that some of these genetic issues can cause trouble with handling infections. By very carefully and specifically supplementing exactly what is needed, the immune system functions in a whole different way. She is even getting metals out without using chelation. Pretty impressive.
I suspect she has some of the missing pieces some of the most ill among us need to know.
5dana8
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posted
Hi riversinger
Is yasko's link the first one at the top?
-------------------- 5dana8 Posts: 4432 | From some where over the rainbow | Registered: Sep 2005
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oxygenbabe
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Dana, go to autismanswer.com and plan to surf through it and read through it for a few months before it starts to make sense. If you have some extra cash, buy her Feburary 2006 DVD's and listen to them a few times.
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riversinger
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It takes a lot of work to study. I've been wishing for one of the mom's on the site to take me on! But you can't make the changes quickly, anyway, so you just have to take your time and dig through the information.
Yasko tracks treatment by using Urine Amino Acids, Urine Toxic Metals, Urine Essential Metals, Organic Acid Tests and Comprehensive Digestive Stool Analysis.
Sounds good, but hubby has already had all these tests done at least 3 - 5 times by other docs who were trying to do the same thing. This was during the 2 1/2 years before he was diagnosed and before any antibiotic treatment.
For the last 3 years we have tried to continue with the supplements to the best of our ability financially while trying to treat the tickborne infections. Do feel the supplements have minimized neuro damage and severity of herxes, but progress has been very very slow.
Riversinger also said -- She sees high ammonia as causing tremors and seizures.
Been there and done that as well. Ammonia does not seem to be an ongoing issue.
Will check out the websites, but just not sure if covering the same old ground will get us anywhere.
I have a nice long list of hubby's "problems" -- some could probably be solved with sufficient funds. Others it seems like I have no answers for or the standard solution did not work.
I do appreciate all the thoughtful responses -- it justs seems like I keep running into the same dilemma -- do I look for another LLMD or is there some other specialist such as an herbalist or endocrinologist or whatever that has the missing piece of the puzzle? It helps to know that I am not alone in this maze.
Bea Seibert
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oxygenbabe
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Well, you have to decide, Bea, by reviewing her DVD's and her work and deciding if it's substantially different.
It seems to me you need to totally fix your husband's methylation cycle and detox abilities before you then try antimicrobials again. That's what I'm going to do for myself anyway.
I actually don't believe that, in regards to Yasko, your husband has 'been there done that.' Having listened to so many hours of DVD's I've concluded she has the kind of synthesizing intelligence across disparate domains, that she sees connections, that others simply don't. That doesn't mean she has the magic bullet answer for everybody, of course. One may have to combine the best of various worlds.
Hope for the best for you and your husband. Posts: 2276 | From united states | Registered: Jun 2004
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riversinger
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Bea, since you have done so many of the tests already, you may be able to use them to see what Yasko might have recommended at the time. Just because she is using the same testing, does not mean she has the same treatment goals.
But you will only be able to tell by looking into her protocol, in depth. It may be that you have already tried it all. I don't know. And what she is doing may not help your husband. I don't know that, either. It certainly isn't simple, or necessarily cheap. I wish we could find something that is both, but it may not be in the cards for those with the most complex problems.
AliG
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up
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But you can't make the changes quickly, anyway, so you just have to take your time and dig through the information.
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