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» LymeNet Flash » Questions and Discussion » Medical Questions » German LTT-MELISA test?

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Author Topic: German LTT-MELISA test?
mikej2323
LymeNet Contributor
Member # 8913

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Has anyone ever heard of the German LTT-MELISA test? If so, would it be effective here in the U.S. and for someone who has been on antibiotics for over a year now? Any research on the test?

Here is a link:

http://www.melisa.org/borrelia-lyme-disease.php

Thanks.

Mike
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Posts: 252 | From Iowa | Registered: Mar 2006  |  IP: Logged | Report this post to a Moderator
GiGi
Frequent Contributor (5K+ posts)
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Yes, MELISA is excellent. Many test positive with LTT who have never before. Dr. K. himself was tested there and for the first time in many years had a positive. I am pretty certain that the German health insurance recognizes and pays for the tests.

Contact them -

The MELISA heavy metal tests are just as important.

The LTT (lymphocite transformation test) done in Berlin (and Karlsruhe)as described below is not the same test as the MELISA LTT as discussed on www.MELISA.org

Take care.

Take care.

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ElaineC
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Hi Mike,

The German LLMDs use this test quite alot, as extra back-up after
doing ELISAs and WBs. It checks for Borrelia specific T-Lymphocytes
in the blood, and they use it to show "active" Lyme.

I've had two LTTs done in Germany, requested by two different very
well known LLMDs there, and carried out in two different specialist
labs with different results!!!Most German docs would dismiss the LTT as non-
standard - it is no longer
covered by German health insurance (which didn't apply to me
anyway!),and costs about �200 or $270
. It takes 3 weeks to process,
and it is strongly recommended that one is antibiotic free for at
least 6 -8 weeks before doing the test. The results vary alot from
lab to lab. It is also recommended that one travels to the lab to
have the blood taken to ensure the sample is as fresh as possible to
yield an accurate result.

The first one I had done was in March 2005. The LLMD sent the blood by courier to a lab in Berlin, so it was there 24
hours later. I was abx free for 8 weeks at the time. The result was
equivocal.

The second one I had done in September 2005 was positive. This time
I attended a prominent Lyme Literate Neurologist in Bonn. He said,
in his experience, results from Berlin were not as accurate as they
should be, as there was a delay in getting the blood to them. This
time I travelled to the lab in Cologne (the same lab that is
considered number one for WBs). I had the blood taken there and it
was processed immediately without delay to ensure freshness and
accuracy. The result was positive. Also, I was abx free for 12 weeks
at this stage, so that could also have been a factor.

I had a huge battle trying to get a German PCP to accept the result,to get 6 weeks IV Rocephin,
even though I was paying privately. My US LLMDs (first Dr.B and now Dr.H) said it is an
antiquated test method, and most docs in the US never heard of
it........although, at the end of the day, a positive result does show Lyme!

Hope this helps

Elaine

Posts: 261 | From Herx-ville!! | Registered: Aug 2006  |  IP: Logged | Report this post to a Moderator
mikej2323
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I'm curious as to why it has never been discussed on this board before...???

Any thoughts on this...???


Mike
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Posts: 252 | From Iowa | Registered: Mar 2006  |  IP: Logged | Report this post to a Moderator
seibertneurolyme
Frequent Contributor (5K+ posts)
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It has been discussed here before. Pretty sure a couple of people had it done. Will try to find the previous thread.

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=040246

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=047210

Bea Seibert

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mikej2323
LymeNet Contributor
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Hmmm...nothing had come up when I searched for it, but obviously there had been some discussion previously. Thanks Bea for locating the thread.

Mike
[email protected]

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mikej2323
LymeNet Contributor
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Ok, so anyone have any insight on how antibiotics would effect this test?

Mike
[email protected]

Posts: 252 | From Iowa | Registered: Mar 2006  |  IP: Logged | Report this post to a Moderator
ElaineC
LymeNet Contributor
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The German LLMDs and labs doing the LTTs told me if you have the test done while taking abx, or too soon after stopping, it can produce false positive results...
Posts: 261 | From Herx-ville!! | Registered: Aug 2006  |  IP: Logged | Report this post to a Moderator
   

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