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» LymeNet Flash » Questions and Discussion » Medical Questions » Now...another deadly pathogen

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Author Topic: Now...another deadly pathogen
Marnie
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In EUROPE:

The same tick that carries Bb, now has been found to carry another pathogen, a newly discovered and newly named one that goes into the mitochondria (powerhouses) of the ovarian cells. This is the FIRST pathogen identified that goes into the mitochondria.

I found the above when catching up with pubmed "lyme" abstracts.

We better find a way to control the tick population.

Posts: 9424 | From Sunshine State | Registered: Mar 2001  |  IP: Logged | Report this post to a Moderator
Aggie
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[Eek!] [Frown]
[shake]

Posts: 28 | From a lyme-twisted place | Registered: Nov 2006  |  IP: Logged | Report this post to a Moderator
ChrisBtheLymie
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Marnie,

Can you provide more info? What is this pathogen called?

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Marnie
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Dipartimento di Patologia Animale, Igiene e Sanita Pubblica Veterinaria, Universita degli studi di Milano, 20133 Milan, Italy.

"An intracellular bacterium with the unique ability to enter mitochondria exists in the European vector of Lyme disease, the hard tick Ixodes ricinus.

Previous phylogenetic analyses based on 16S rRNA gene sequences suggested that the bacterium formed a divergent lineage within the Rickettsiales (Alphaproteobacteria). Here, we present additional phylogenetic evidence, based on the gyrB gene sequence, that confirms the phylogenetic position of the bacterium.

Based on these data, as well as electron microscopy (EM), in situ hybridization and other observations, we propose the name 'Candidatus Midichloria mitochondrii' for this bacterium.

The symbiont appears to be ubiquitous in females of I. ricinus across the tick's distribution, while lower prevalence is observed in males (44 %). Based on EM and in situ hybridization studies, the presence of 'Candidatus M. mitochondrii' in females appears to be restricted to ovarian cells.

The bacterium was found to be localized both in the cytoplasm and in the intermembrane space of the mitochondria of ovarian cells. 'Candidatus M. mitochondrii' is the first bacterium to be identified that resides within animal mitochondria."

PMID: 17082386
Int J Syst Evol Microbiol. 2006 Nov;56(Pt 11):2535-40

Let's hear it for the Italian doctors and researchers...most of the "truths" are coming from there!

Posts: 9424 | From Sunshine State | Registered: Mar 2001  |  IP: Logged | Report this post to a Moderator
   

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