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» LymeNet Flash » Questions and Discussion » Medical Questions » Can Biaxin tablets be cut? (not XL)

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Author Topic: Can Biaxin tablets be cut? (not XL)
trueblue
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I've just read through 25 pages of googled stuff and searched here.

The label say to not cruch or chew, yuck, but...

Can plain old generic Clarithromyocin be split, if necessary, to ramp up to full dosage?

If that's not such a good idea... Could it be split and shoved in a gelatin capsule?


I usually do better starting out at half dose and split half does better. Is this a med I can do this with?

Does anyone have any experiences doing this?


Sorry to be the pest of the universe lately. [Frown]
Thanks for any thoughts or input.

trueblue

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charlie
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Hi TB....from what I've been told if the pill isn't scored it wasn't meant to be separated and the dose may be distributed unequally in there.

So if it was me, I'd crush the pill up and divide it between 2 caps, at least the distribution might be better that way.

Charlie

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trueblue
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Thanks Charlie,
Definately not scored and film-coated. They clearly state not to cut the XL but it's sketchy on the plain old regular ones.

I was thinking if the first dose is a bit much I might try just cutting it and shoving it in a gelatin cap but am not sure this is sufficient as far as coating goes.


I only took Biaxin for a month 12 years ago and it was difficult. I had just come off IV Rocephin at the time and had a much lower germ load than presently.

I'll try a 500 the first day and then call the pharmacy and talk to them if no one has a sure fire answer by then.


Thanks as always, for looking out for me, buddy. [kiss]

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Carol in PA
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Blue,
You are going to try a new med right before you go for gall bladder surgery?

What, are you nuts?

Carol

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trueblue
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No Carol!
The surgery is being put off for another week I think and was going to wait until after to play with the biaxin.


Only slightly nuts [Big Grin]

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Carol in PA
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Oh.

[Roll Eyes]

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trueblue
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[Big Grin]

Just worrying needlessly in advance. [Wink]

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treepatrol
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I know Biaxin XL is time release ask you pharmacist.

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Do unto others as you would have them do unto you.
Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.

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Aniek
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This is a question you should ask a pharmacist.

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charlie
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I got this info years ago in a matter unrelated to lyme from a family member who is, in fact, a pharmacist. She told me that if a pill isn't scored to be separated it's possible that the active ingredient isn't evenly distributed in the filler.
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trueblue
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Thanks all,
So the answers is no one has the foggiest notion. [Big Grin]
I'll call the pharmacy but in general pharmacists are just guessing too. Unless you get one actually willing to look it up.


There's a label that says do not crush or chew. To my mind it seems it would release slower if the cut tab was in a capsule than powder in a capsule.


I do get the part about not being evenly distributed but could it be in all one end? How much could it really vary? 225 mg vs 275?


Tree,
In truth I think the pharmacist put the label for the XL on... although this is not. Just like the one on Doxy that says you can take it with milk.


I'm sorry, I don't know what possessed me to ask. I didn't mean to cause a fuss about something so unimportant. I was just wondering is all.

Thanks

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robi
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call the manufacturer to find out the distribution of active ingredient.

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Now, since I put reality on the back burner, my days are jam-packed and fun-filled. ..........lily tomlin as 'trudy'

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trueblue
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quote:
Originally posted by robi:
call the manufacturer to find out the distribution of active ingredient.

Oh, duh! Thanks Robi, great idea!

>cue mission impossible music< [Wink]
I've never heard of this manufacturer, I'll try and google them.

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trueblue
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I was just talking to a friend and mentioned the Biaxin and she said her script was for 250s and the pharmacy gave them to her as cut down 500s.

I guess at least one pharmacist thinks it's alright if he dispensed them that way.

------------------------------------------------------


Cave, I had a doc prescribe a med that had sulfa in it last year. I am allergic to sulfanomides (sp?). I called 3 pharmacies.

One said, what sulfa? That's not sufla! He had looked it up and didn't understand the chemical name or the diagram of the structure. I had to read the chemical name to him until he heard the word sulfa in it. [Roll Eyes] He still wasn't sure.

#2 told me that form of sulfa may or maynot be a problem for sulfa allergic individuals considering the way it was structured. It could go either way.

The 3rd said... well, you could take it but make sure to keep the Benedryl close.


The second 2 did ask how my allergy manifests and were fairly sure I would only get giant hives and not go into anaphlactic(sp?) shock.

The first one is still thankful he had someone else to copy from in chemistry class, no doubt.

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