CaliforniaLyme
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Member # 7136
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1: Int Microbiol. 2001 Dec;4(4):209-15. Links Susceptibility of motile and cystic forms of Borrelia burgdorferi to ranitidine bismuth citrate. Brorson O, Brorson SH. Department of Microbiology, Vestfold Sentralsykehus, Tonsberg, Norway.
Gastrointestinal symptoms accompanying Lyme disease have not been considered in the treatment of Lyme patients yet. Here we examine the effect of ranitidine bismuth citrate (RBC) on motile and cystic forms of Borrelia burgdorferi in vitro, to determine whether it could cure this bacterial infection in the gastrointestinal tract. When motile forms of B. burgdorferi were exposed to RBC for 1 week at 37 degrees C, the minimal bactericidal concentration (MBC) was > 64 mg/ml. At 30 degrees C, the MBC was > 256 mg/ml. When the incubation lasted for 2 weeks at 37 degrees C, the MBC dropped to > 2 mg/ml. Bismuth aggregates were present on the surface of B. burgdorferi when RBC > or = MBC, as shown by transmission electron microscopy (TEM). Cystic forms of B. burgdorferi, exposed to RBC for 2 weeks at 37 degrees C, were examined by cultivation in BSK-H medium (Sigma B3528). They were stained with acridine orange (pH 6.4, pH 7.4) and studied by TEM. The MBC for RBC for young cystic forms (1 day old) and old cysts (8 months old) was estimated to be > 0.125 mg/ml and > 2 mg/ml, respectively. Bismuth aggregates were attached to the cysts and, in some, the pin-shaped aggregates penetrated the cyst wall. The bismuth aggregates also bound strongly to blebs and granules of B. burgdorferi when RBC > or = MBC. When B. burgdorferi is responsible for gastrointestinal symptoms, bismuth compounds may be candidates for eradication of the bacterium from the gastrointestinal tract.
PMID: 12051564 [PubMed
I noticed that Pepto-Bismol sometimes darkens the tongue/stool. Why does this happen and how long does it last? The active ingredient in Pepto-Bismol contains bismuth. When a small amount of bismuth combines with trace amounts of sulfur in your saliva and gastrointestinal tract, a black-colored substance (bismuth sulfide) is formed. This discoloration is temporary and harmless. It can last several days after you stop taking Pepto-Bismol. Individual bowel habits, your age (the intestinal tract slows down with age), and the amount of the product taken all help to determine how long Pepto-Bismol is in your system.
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
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klutzo
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HI Cal Lyme, Marnie turned me onto the use of PB to kill Bb in the gut awhile back. I now take it every night for one week, about every 1 1/2 months. My stomach reminds me if I forget!
Klutzo
Posts: 1269 | From Clearwater, Florida, USA | Registered: May 2004
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TerryK
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Hadn't heard of this to kill borrelia but I know it is used sometimes in treatment for h.pylori. Terry
Posts: 6286 | From Oregon | Registered: Jan 2006
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My feeling is Pepto Bismul contains Aluminum so we stay away from it.
We all are off the charts for Aluminum already.
Lyme x 9
I also thought a woman died from IV Bismuth that some Dr's were infusing for Bb. Don't know details maybe I dreamed that?
Posts: 399 | From Texas | Registered: Apr 2005
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Beverly
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When I was checked for toxins, my bismuth was high. I practically lived on pepto my whole life! I still take it sometimes, but not a lot.
It does help my stomach though, always did.
Posts: 6639 | From Michigan | Registered: Jun 2001
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