Med Hypotheses. 2006 Dec 29; [Epub ahead of print] Lyme borreliosis and multiple sclerosis are associated with primary effusion lymphoma.
Batinac T, Petranovic D, Zamolo G, Petranovic D, Ruzic A. Department of Dermatovenerology, Rijeka University Hospital, Kresimirova 42, 51000 Rijeka, Croatia.
Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by chronic inflammation and demyelination. Studies suggested that the viral, especially Epstein-Barr virus infection, and bacterial infections, especially Borrelia burgodorferi infection, play a role in etiology of MS. MS prevalence parallels the distribution of the Lyme disease pathogen B. burgdorferi. Criteria used for diagnosis of MS can also be fulfilled in other conditions such as Lyme disease, a multisystem disorder resulting from infection by the tick-borne spirochete, B. burgdorferi.
In the late period of Lyme disease demyelinating involvement of central nervous system can develop and MS can be erroneously diagnosed. A Lyme borreliosis can mimick central nervous system lymphoma. Also, B. burgdorferi has been implicated not only in etiology of MS, but also in etiology of lymphoma.
Studies suggested that there is an increased risk of non-Hodgkin lymphoma in patients, who had a history of autoimmune diseases such as MS and that both non-Hodgkin's lymphomas and Hodgkin's disease were associated with Epstein-Barr virus infection. A small group of lymphomas called primary effusion lymphomas (PEL) is a recently individualized form of non-Hodgkin's lymphoma (WHO classification) that exhibit exclusive or dominant involvement of serous cavities, without a detectable solid tumor mass. These lymphomas have also been linked to Epstein-Barr virus and human herpes virus type 8 infections but virus negative cases have been described.
Therefore, we propose that MS and neuroborreliosis are linked to central nervous system primary effusion lymphomas. As a first step in confirming or refuting our hypotheses, we suggest a thorough study of CSF in the patients suspected for the diagnosis of MS and Lyme borreliosis.
PMID: 17197115 [PubMed - as supplied by publisher]
-------------------- **Eat Chocolate** Posts: 942 | From USA | Registered: Mar 2005
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Boomerang
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No, humanbeing, my hubby doesn't get routine MRI's... I wonder if he should. He had CT scan, MRI when he first got sick. Hasn't had any since then.
yes, i get regular MRI's; every 2 yrs or so..but was diagnosed with MS after MRI's.
i have lesions in both my brain and cervical spine. Over the years, i had exasberations including losing hand coordination, tingly feet, hands the normal stuff; but lucky to have been categorized as benign..
i now see a LLMD in CT and am being treated with antibiotics..i have a low CD57 (was 21 now 24) and immune complexes in alert status, but am coming along very nicely!
I, like you will be starting Mepron adding Zith to Minocycline soon!
Determined to rid myself of the Bb bacteria that has been causing me grief for lots of years!
Go get those MRI's as well as a ct scan..listen to your doc. I have a feeling we see the same one; if so I believe you are in very good hands.
Lymedad, If I may suggest: have your loved one begin to read all the similarities there are between MS/Lyme..I did and sought out a very good LLMD to get tested correctly. I am now being treating for borrelia: this after years of taking CRAB injections.
there is no cure for MS so why not think about treating the cause of the illness rather than treating the symptoms?
gosh, I'm not the best one to answer this question: doc P sure could..but here goes.
IMO they are the same..with all I've read and by my test results! Can lyme turn into MS? both relapse and remit, both present similarly..I was treating for my symptoms (steroids etc.) then CRABS not noticing a change. What I've found is if left untreated my immune system was/is in bad shape.
the saddest part is the insurance companies ruling over who gets to see what doctor? and they dare talk of preventative medicine. Eating healthy, exercise, etc etc.
Of course, those things are necessary, but finding out what the problem is, is also VERY necessary!
How could a doctor be out of network? It's absurd, yet I realize it's part of our culture!
Perhaps, has I cross my fingers, the ABC special will have a chance to tell our story, and begin to allow all of us fair treatment.
My best to you, tory
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