LymeNet Flash: antidepressenats/ braind damage question

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»	LymeNet Flash » Questions and Discussion » Medical Questions » antidepressenats/ braind damage question

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Topic: antidepressenats/ braind damage question

adamm
Unregistered

posted

I read somewhere that he neurotoxin quinolinic acid is synthesized from serotonin, or something like that. Do SSRI's (prozac, luvox, etc) accelerate this process? What about tryciclics?

I also read in an old post that a Dr. Cheney found that antidepressants cause lesions to form independent of microbe activity? Could someone elaborate on this?

Thanks all,
Adam

IP: Logged |

adamm
Unregistered

posted

I should also like to mention that after

starting Anafranil (tricyclic antidepressant),

the severity of my brain fog was dramatically

reduced. Can anyone formulate an educated

hypothesis as to the nature of the mechanism

underlying this phenomenon? I read somewhere

that tricyclic's were actually shown to be neuro-

protective...

All the best for a prompt recovery,

Adam

IP: Logged |

kelmo
Frequent Contributor (1K+ posts)
Member # 8797

posted

I don't know, but my daughter wouldn't be alive without them. Pick your poison.

Kelly

Posts: 2903 | From AZ | Registered: Feb 2006 | IP: Logged |

klutzo
Frequent Contributor (1K+ posts)
Member # 5701

posted

Adam,
It's been a long time since I read Dr. Cheney on this particular subject, but if I remember correctly, he said that the brain is not stupid, and eventually recognizes that certain neurons are overfiring, and kills those neurons as being defective.

SSRI's work by making neurons overfire to keep the serotonin (and sometimes norepinephrine) from being taken back up. Thus, the supply is never reduced.
- - - - - - - - --

Theoretically, if you are low in norepinephrine and take a drug that raises it, it should make you more alert and clear-headed. Tricyclics also extend stage IV slow wave sleep, which should make you more rested, ie. less foggy.

Klutzo

Posts: 1269 | From Clearwater, Florida, USA | Registered: May 2004 | IP: Logged |

Lymetoo
Moderator
Member # 743

posted

That's scary about the SSRI's!! I've never taken one, but my husband has been on Prozac since it first came out....like 17 yrs.

I've been on tricyclics for about the same amount of time. Glad I've stuck to them....and not switched over. I have tried to get off of them...no such luck.

The side benefit of improved sleep is one of the main reasons I'm still on them.

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001 | IP: Logged |

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