Topic: Evil Genius Alan Barbour: Abx for Ticks not for patients!!!!
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
So how many days of abx do the TICKS get? This abstract MADE ME SICK!!!! AGH AGH AGH!!!!!!!! ***********************************************
1: PLoS ONE. 2007 May 2;2:e405.
Antibiotic Treatment of the Tick Vector Amblyomma americanum Reduced Reproductive Fitness.
Zhong J, Jasinskas A, Barbour AG. Department of Microbiology and Molecular Genetics, Department of Medicine and Pacific-Southwest Center for Biodefense and Emerging Infections, University of California Irvine, Irvine, California, United States of America.
BACKGROUND: The lone star tick Amblyomma americanum is a common pest and vector of infectious diseases for humans and other mammals in the southern and eastern United States.
A Coxiella sp. bacterial endosymbiont was highly prevalent in both laboratory-reared and field-collected A. americanum. The Coxiella sp. was demonstrated in all stages of tick and in greatest densities in nymphs and adult females, while a Rickettsia sp. was less prevalent and in lower densities when present.
METHODOLOGY/PRINCIPAL FINDINGS: We manipulated the numbers of both bacterial species in laboratory-reared A. americanum by injecting engorged nymphs or engorged, mated females with single doses of an antibiotic (rifampin or tetracycline) or buffer alone. Burdens of the bacteria after molting or after oviposition were estimated by quantitative polymerase chain reaction with primers and probes specific for each bacterial species or, as an internal standard, the host tick.
Post-molt adult ticks that had been treated with rifampin or tetracycline had lower numbers of the Coxiella sp. and Rickettsia sp. and generally weighed less than ticks that received buffer alone.
Similarly, after oviposition, females treated previously with either antibiotic had lower burdens of both bacterial species in comparison to controls.
Treatment of engorged females with either antibiotic was associated with prolonged time to oviposition, lower proportions of ticks that hatched, lower proportions of viable larvae among total larvae, and lower numbers of viable larvae per tick.
These fitness estimators were associated with reduced numbers of the Coxiella sp. but not the Rickettsia sp.
CONCLUSION/SIGNIFICANCE: The findings indicate that the Coxiella sp. is a primary endosymbiont, perhaps provisioning the obligately hematophagous parasites with essential nutrients.
The results also suggest that antibiotics could be incorporated into an integrated pest management plan for control of these and other tick vectors of disease.
PMID: 17476327
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
This mans nuts
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
Hallelujah to THAT, Tree*)!*)!!!!!!!!!
He doesn't believe in real abx tx for people!!!!!!!!! But TICKS?! Heck, I hope they felt a lot better after his experiment!!!!!!!!!! (Before he vivisected them that is*)!!!!!!!!!
Barbour proves his idiocy- AGAIN!!!!!!!!!!!!
(My mother is a professor where he is though, and you know what she heard through the grapevine- that even though officially he doesn't believe in longterm abx treatment that a member of the facultys spouse got Lymed and he treated him with longterm abx!!!!!!!!!! I heard that from my Mom!!!!!!!!!!!!!!!!!!! He is not supposed to be a treating doc!!!!!!!!!!!!!!! So I was shocked!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)
He hols a lot of patents on Lyme realted stuff and he wrote a TERRIBLE terrible book with many quotable Barbourisms!!!!!!!!!
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
I wonder sometimes these so called drs > maybe they picked a little something up from there patients or handeling ticks and are themselves infected? Mentally that what he just proposed is well nuts!
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
On a serious note, I don't get how he could achieve control over the disease out there. Too many ticks, too many infected animals who I understand pass on infections to the ticks that bite them.
Posts: 13117 | From San Francisco | Registered: May 2006
| IP: Logged |
posted
Did it say ticks treated with abx had LOWER LEVELS of infection? That is, the infection was not eradicated! So, even ticks need long-term treatment, apparently!
But the most worrisome thing in this study is, that it clearly maximizes the probability of creating even more antibiotic resistant strains of spirochetes! Thus, this research, though it may not seem quite totally useless (though I agree, it's pretty close) at the outset, may in fact be less than useless; i.e., harmful, and should indeed be discontinued. If anybody has a chance, and is good at such things, you should send a copy of this to some kind of "disease control" government agency! Again, there's a good chance the this 'research'... is worse than useless; and is, in fact, downright dangerous!
DaveS
Posts: 4567 | From ithaca, NY, usa | Registered: Nov 2000
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/
UBBFriend: Email this page to someone!
![[shake]](graemlins/shake.gif)
![[rant]](graemlins/rant.gif)
![[puke]](graemlins/puke.gif)
![[Big Grin]](biggrin.gif)
Printer-friendly view of this topic