posted
I read that a lot of people take doxycline for Lyme. My doctor prescribed me minocyline. Is it as good? Is anyone else taking this? I'm kind of confused about antibiotics.
Posts: 248 | From Tejas | Registered: Jun 2007
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ByronSBell 2007
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posted
Yes minocycline is good, this is one of the first choices of most lyme literate medical doctors but, there are better ones out there. This is a good starting antibiotic for you, beware the the herx reaction!
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Vermont_Lymie
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posted
Lauren,
From what I understand, minocycline is a very powerful and good abx to use for lyme. If you do a search here on lymenet, using "minocycline" and "mino", you will get alot of information on it!
My llmd just started me recently on mino, but I am taking a very low dose for now, along with high-dose amoxy. Some folks get alot of side effects at first with mino, esp. dizziness.
Best wishes.
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butchieboo
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posted
Acording to my pharmacist...doxycicline is derived or is a molecule different than the original abx Minocycline...thus probably more potent...
To correct previous post....I believe doxycicline is the preferred first oral abx along with ammoxycilin used by many LLMD's....
At least it has been my experience.
I have never had the former but was put on the latter immediately after diagnosis and a few times since.
posted
I was originally put on doxy, then switched to mino as spring approached as I spent a lot of time outside. Mino is good.
The cyclines work on one of the three forms of borrelia ... so at some point you will have to go after the other forms as well.
-------------------- sixgoofykids.blogspot.com Posts: 13449 | From Ohio | Registered: Feb 2007
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TerryK
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posted
My LLMD put me on mino first. I couldn't tolerate it and was put on doxy.
Mino is very good at penetrating the CNS. http://www.postgradmed.com/issues/1997/04_97/cunha_1.htm Minocycline Minocycline is a second-generation, long-acting tetracycline that was introduced in the same era as doxycycline. The two drugs have many common attributes: long half-life, once- or twice-daily administration, excellent bioavailability, and equivalent blood and tissue levels whether administered intravenously or orally. However, the two drugs differ in several important respects.
CNS infection Pharmacokinetically, minocycline and doxycycline are both highly lipid-soluble. However, compared with conventional tetracycline, minocycline is ten times more lipid-soluble whereas doxycycline is only five times more lipid-soluble. The clinical importance of this characteristic is that minocycline has particularly good tissue penetration and excellent CNS penetration; although doxycycline does penetrate the CNS, it does not do so to the degree that is achievable with minocycline
Posts: 6286 | From Oregon | Registered: Jan 2006
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posted
Thanks for the info, Terry!! I always thought drs put new patients on doxy because it would kill out ehrlichiosis, which can be deadly if you have it.
So does mino kill out ehrlichiosis??
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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TerryK
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posted
tutu wrote:
quote: I always thought drs put new patients on doxy because it would kill out ehrlichiosis, which can be deadly if you have it.
Didn't know that. Thanks for mentioning it.
tutu wrote:
quote: So does mino kill out ehrlichiosis
I know next to nothing about ehrlichiosis but I did find this.
Rev Med Chir Soc Med Nat Iasi. 1998 Jul-Dec;102(3-4):65-8.Links [An update on human ehrlichiosis][Article in ]
Corcaci DC. Clinica de Boli Infecţioase, Facultatea de Medicină, Universitatea de Medicină Gr. T. Popa, Iaşi.
Human ehrlichiosis is a potentially lethal infections due to a new gram-negative microorganism. The first human case was reported in 1953 in Japan. Two of the animal agents are involved in human disease: Ehrlichia chaffeensis, Ehrlichia sennetsu. A third Ehrlichia type agent causes the disease in human beings only--Ehrlichia granulocytophila. The tick is natural vector; the highest frequency was observed in May-July, in the United States; the most important clinical signs are: fever, anorexia, rush, dyspnea etc.; the specific treatment consists in tetracycline administration (doxycycline minocycline) for up to seven days.
PMID: 10756846 [PubMed - indexed for MEDLINE]
According to Dr. S's book on Babs - Doxy may have an effect on it. Doxy also seems to work somewhat for bartonella.
Terry
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charlie
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posted
according to what i read doxy means Derived from OXYtetraCYCLINE....just put the caps together.
don't know if that's worthwhile info or an exercise in creative nomenclature....
Charlie
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tailz
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posted
My doctor gave me Ceftin (reluctantly) - doesn't matter - I can only tolerate it a few days.
But he pushes Diflucan. Gave me a sheet of paper that says Lyme is gone with 3 months of Diflucan. I don't believe it. It does nothing for my head and spine symptoms.
I'm trying to figure out why he's not using a drug that will kill more than just Lyme, especially since I spent quite a few years on minocycline for acne - and it kept me zit - and apparently Lyme and ehrlichia free.
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butchieboo
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there is a doctor in Germany I believe that uses Diflucan(antifungal) for a number of months and then uses penicillin to successfuly treat lyme disease and all it's buddies...
I believe the jury is still out deliberating this doctors success rate.
I'm taking minocycline 2X a day and diflucan 1X a week. Is that okay to take them together?
[ 30. June 2007, 09:09 AM: Message edited by: LaurenTurner ]
Posts: 248 | From Tejas | Registered: Jun 2007
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CaliforniaLyme
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posted
Doxy is usually used before Minocycline because of more side effects with mino and because Doxy also treats Ehrlichosis and has some effect against babs as well- but you may have job that keeps you in sun...??? Doxy makes you ultra sun sensitive...
Mino is very powerful-
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
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Vermont_Lymie
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posted
Hi Lauren,
Also, I have read here on lymenet and elsewhere that it is good to take extra Vitamin C if you are on minocycline.
I think that is good advice (it is supposed to help prevent side-effects like darkened teeth), so now I am taking 1.5-2 grams/day, split in the morning and evening, Vit C (in Ester-C form with bioflavanoids). Hope that helps.
I am not a doctor, and it is always good to do one's own research. So this advice is just in my opinion; it is what I am doing!
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