Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Is THIS what is in the saliva of the tick that helps Bb "buy time" to infect?
Something ALKALINE?
It appears the infamous lizard has a LOT of cAMP in it's blood.
It appears cAMP can cause a rise in alkaline phosphatase blood levels.
cAMP ALSO activates HSL and lipolysis while insulin potently reduces cAMP levels.
It appears the short chain fatty acids also cause a rise in alkaline phosphatase (throwing off the Omega 3-6 balance - favoring the 3s).
This lizard would HAVE to make a lot of alkaline phosphatase to counter all the formic acid from the ants it loves to devour.
Because...Formic acid looks to reduce cAMP.
If this pathogen triggers the formation of formic acid...
Formic acid looks to impact tryptophan levels...negatively.
***"Local depletion of tryptophan may be immunosuppressive for T cells via activation of the stress response kinase GCN2 pathway, leading to T cell arrest and anergy."***
It should be pretty clear that increasing cAMP is important. However...I'll try hard to simplify an abstract I read:
1. Parathyroid hormome increases cAMP which increases alkaline phosphase.
2. Other substances that increase cAMP in these cells (forskolin, prostaglandin E2, 8-bromoadenosine cAMP and 3-isobutyl-1-methylxanthine) also increased enzyme activity.
3. By comparison, increasing the concentration of calcium in the culture medium lowered the magnitude of the maximal AP response (alkaline phosphatase).
Get alkaline phosphatase up via Forskolin and get Ca levels down.
"A search through the literature turned up curcumin, a weak inhibitor of ER calcium pumps."
Maybe the combination?
Curcumin must be taken with a fat...like warm 1/2 and 1/2...sorta thing.
Can I simplify? I'll try...
Lizard = lots of cAMP = lots of alkaline phosphatase = counters formic acid which looks to deplete tryptophan which impacts the "health" of our immune fighting cells.
Get cAMP levels up, but we also have to get Ca down in order to make enough alkaline phosphatase.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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aklnwlf
Frequent Contributor (5K+ posts)
Member # 5960
posted
Huh? Marnie my dear, this is really putting the old brain to a test especially seeing how I'm on my third alcoholic beverage to depress my central nervous system since it's 4:34 a.m.!!!
I'm already too Alkaline, almost black, but getting more purple on the PH strips....
My Magnesium is low so I think my Ca is low so all I have to take is the Forskolin?
What form? and what mg?? What is Forskolin? And it produces cAMP right?
I'll do a search on this site and see what else you've submitted recently on this subject. Absolutely fascinating!
Thanks Marnie!!
-------------------- Do not take this as medical advice. This comment is based on opinion and personal experience only.
Alaska Lone Wolf Posts: 6147 | From Columbus, GA | Registered: Jul 2004
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butchieboo
Unregistered
posted
Marnie,
Thanks again for simplification.
I do have a question. I have a juicer. Exactly what fruit or vegetable might I find the curcumin in so that I might use my juicer to extract said substance and ingest it in this manner?
I have used a combination of Kale,Parsley,red cabbage,tomato's,Broccoli and garlic(at times).
This is a recipe I found in a book somewhere for bronchitis. But it does seem to help my energy and weight gain.
Please tell me if any of these or any others should be added or deleted for desired effect?
Oh yeah, I used to make, a little beet juice, to wash down(as a chaser), the taste of the other stuff.
luvs2ride
Frequent Contributor (1K+ posts)
Member # 8090
posted
Marnie,
I have been supplementing calcium on an "as needed" basis for over 1 yr. The "as needed" is determined by the ph of my first morning urine. If I am too acidic, I take calcium. If I am alkaline, I do not.
If I understand what you say, we need to be low in calcium. (man, that goes against everything I have ever read about Rheum. Arthritis)If so, then your theory would explain why I am consistantly in more pain on alkaline days than I am on acidic days. I can tell the minute I stand up each morning whether I am going to be alkaline or acidic just by my level of pain.
Until now, my theory behind that was that on acidic days I was dumping toxins through my urine thereby decreasing my pain.
Am I following you correctly here? Should I stop supplementing calcium and begin taking forskolin? What about magnisium? I recently began taking a tablespoon of mag in hot water before bedtime. I very quickly hit bowel tolerence which makes me think I wasn't needing mag.
Luvs
-------------------- When the Power of Love overcomes the Love of Power, there will be Peace. Posts: 3038 | From america | Registered: Oct 2005
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
With Mg-ATP levels low...with Mg low...the body, in order to balance the pH, looks to use our most abundant mineral, calcium. We have a LOT of calcium! It will have to come from the bones... and it will.
At the outset of lyme, it looks like Mg levels dive and potassium goes up initially. But over a LONG time...eventually potassium will drop.
We can't "hang onto" K when Mg levels drop too far.
Curcumin is in tumeric which is in the spice, Curry. I do not know of other sources. Anyone else find another source?
Our bone health depends on calcium, magnesium, vitamin D, boron, and phosphorus.
NOT JUST CALCIUM.
These are supposed to be in balance.
Getting them in balance is the hard part!
I will not post dosages of Forskolin and/or curcumin and times to take. It is "all over the board" as far as who (on the internet) suggests how much to take. No RDA to go by!
Personally, I am taking both 2x/day in small doses and feel NO DIFFERENT. I added the EFAs as a "fatty acid" source to work with curcumin.
I want to see if these cause weight loss.
Okay...I'm lazy...jogging/walking in the Florida heat to lose weight is not "my thing" and the young fit gals at the exercise places are intimidating.
;-)
Luvs...more pain when alkaline? Hummm...I've often wondered if the pain of herxes is caused by too much Zn and Mn being released when Bb is destroyed??? They are toxic in high levels too.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
P.S. Luvs...you might consider a product called Juvenon. Look very closely at what is IN it...the COMBINATION.
It was formulated by a brilliant biochemist, Bruce Ames, from Berkeley.
The 2 capsules might be best taken at 4pm.
This supplement is to help "heal the mitochondria", help to restore energy levels, etc.
Some say this "reverses aging".
I have no financial or otherwise connections to this supplement manufacturer or any other. Nor do I have any connections to any PERSON - doctors included.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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luvs2ride
Frequent Contributor (1K+ posts)
Member # 8090
posted
Thanks Marnie.
You have talked about and I have looked at Juvenon before. I'm all for reversing aging!
I don't add or take away from my regimen without running it past my doctor. I believe I will bring up Juvenon on next visit.
Luvs
PS: When I looked at Juvenon from Dr Weil's website, I could not determine what the ingredients were. Do you have a better source?
-------------------- When the Power of Love overcomes the Love of Power, there will be Peace. Posts: 3038 | From america | Registered: Oct 2005
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butchieboo
Unregistered
posted
Hey Marnie,
I noticed you said you have no connection to any person! in your last post!
Could that be because you talk, in the same technical manner on dates!? LOL!
Hey, don't let those "hard bodies" intimidate you! You seem to have a 36 24 36 mind!
Hope I spelled all those correctly. The printing is very small and I am old...
Serving size is 2 tablets with food. The instructions say the 2 tablets can be taken together or apart.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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Vermont_Lymie
Frequent Contributor (1K+ posts)
Member # 9780
posted
quote:Originally posted by Marnie: When our eyes met, it was love at first sight many moons ago. We both have a glazed look:
I talk "medical" and my husband's eyes glaze over. He talks "stock market/investments" and MY eyes glaze over.
Sounds familiar!
Posts: 2557 | From home | Registered: Aug 2006
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