Topic: 2007: 16 month old girl with Bartonella encephalopathy, Gullain-Barre Syndrome
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
1: Pediatr Infect Dis J. 2007 Sep;26(9):860-862.
ENCEPHALOPATHY COMPLICATED BY GUILLAIN-BARRE SYNDROME AND HYDROCEPHALUS AND ASSOCIATED WITH ACUTE BARTONELLA QUINTANA INFECTION.
Mantadakis E, Spanaki AM, Psaroulaki A, Fitrolaki D, Minadakis G, Michaeloudi E, Tselentis Y, Briassoulis G. From the *Department of Pediatrics, Pediatric Intensive Care Unit, and �Laboratory of Clinical Bacteriology, Parasitology, Zoonoses, and Geographical Medicine, University Hospital of Heraklion, Heraklion, Crete, Greece.
We describe a 16-month-old girl who suffered from encephalopathy leading to intensive care unit hospitalization, complicated by Guillain-Barre syndrome and hydrocephalus, and who had serologic and molecular evidence of central nervous system infection by B. quintana.
The possible association of B. quintana with Guillain-Barre syndrome and hydrocephalus has not been previously described and demonstrates the growing spectrum of neurologic complications of Bartonella spp. infections.
PMID: 17721391
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
10 year old girl with Gullain Barre & Bartonella-
1: Pediatr Infect Dis J. 2006 Jan;25(1):90-1. Links Bartonella henselae infection associated with Guillain-Barre syndrome.Massei F, Gori L, Taddeucci G, Macchia P, Maggiore G. Dipartimento di Medicina della Procreazione e della Et� Evolutiva, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
This is the first report of Guillain-Barr� syndrome (GBS) related to Bartonella henselae infection. A 10-year-old girl had difficulty walking and marked myalgia. The search for all causes known to trigger GBS was negative. She was treated with intravenous immunoglobulins and recovered. Because she lived in a rural area and had a history of kitten contact, a specific serology for B. henselae infection was performed and confirmed an ongoing infection. She did not show any clinical typical feature of cat-scratch disease. B. henselae infection should be considered in the wide etiologic spectrum of GBS.
PMID: 16395116
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
1: J Neurol. 1993 Sep;240(8):506-7.Links Guillain-Barr� syndrome during treatment with ofloxacin.Schmidt S, Cordt-Schlegel A, Heitmann R. PMID: 8263558
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
Remember- Q fever is tickborne- ********************************
1: Eur J Clin Microbiol Infect Dis. 1994 Aug;13(8):658-9.Links Guillain-Barr� syndrome associated with acute Q fever.Bernard E, Carles M, Laffont C, Durant J, Dellamonica P. Archet Hospital, Nice, France.
Several bacterial and viral agents have been implicated in the pathogenesis of the Guillain-Barr� syndrome, an acquired immune-mediated disorder. A case of Guillain-Barr� syndrome associated with acute Q fever is described. Coxiella burnetii should therefore be added to the list of microorganisms capable of inducing the Guillain-Barr� syndrome.
PMID: 7813497
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
OKAY what is intersting about THIS is that jejuni is usually treated with quinolines!!!! SO WHEN did GB emerge???? DId it emerge as part of reaction to tx for jejuni? As a Herx? *********************************************
Lindes DM. Related Articles, Links Severe Guillain-Barre syndrome associated with Campylobacter jejuni infection. J Am Board Fam Pract. 1999 Nov-Dec;12(6):505. No abstract available. PMID: 10612373
Hagensee ME, Benyunes M, Miller JA, Spach DH. Related Articles, Links Campylobacter jejuni bacteremia and Guillain-Barre syndrome in a patient with GVHD after allogeneic BMT. Bone Marrow Transplant. 1994 Mar;13(3):349-51. PMID: 8199580
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
1: Ann Neurol. 1978 Oct;4(4):386-7.Links
Quinine sulfate for pain in the Guillain-Barr� syndrome.
Nixon RA. PMID: 727746
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
not related to theme above but good new one- ********************************************* -------------------------------------------------------------------------------- 1: Appl Environ Microbiol. 2007 Aug 10;
Mixed infections, cryptic diversity, and vector-borne pathogens: Evidence from Polygenis fleas and Bartonella.
Abbot P, Aviles AE, Eller L, Durden LA. Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA, Department of Biology, Georgia Southern University, P.O. Box 8042,Statesboro, GA 30460, USA.
Co-infections within hosts present opportunities for horizontal gene transfer between strains and competitive interactions between genotypes, and thus can be a critical element of the lifestyles of pathogens.
Bartonella are alpha-Proteobacteria that parasitize mammalian erythrocytes and endothelial cells.
They are thought to be vectored by various biting arthropods, such as fleas,
ticks
, mites, and lice, and are commonly cited as agents of various emerging diseases.
Co-infections by different Bartonella strains and species can be common in mammals, but little is known about specificity and co-infections in arthropod vectors.
We surveyed the rate of mixed infections of Bartonella in flea vectors (Polygenis gwyni), parasitizing cotton rats (Sigmodon hispidus) in which previous surveys indicated high rates of infection. We found that nearly all fleas (20 of 21) harbored one or more strain of Bartonella, with rates of co-infection approaching 90%. A strain previously identified as common in cotton rats was also common in their fleas. However, another common strain in cotton rats was absent from P. gwyni, while a rare cotton rat strain was quite common in P. gwyni. Surprisingly, some samples were also co-infected with a strain phylogenetically-related to B. clarridgeiae, which is typically associated with felids and ruminants. Finally, a locus (pap31) that is characteristically borne on phage in Bartonella was successfully sequenced from most samples.
However, sequence diversity in pap31 was novel in the P. gwyni samples, relative to other Bartonella previously typed with pap31, emphasizing the likelihood of large reservoirs of cryptic diversity in natural populations of the pathogen.
PMID: 17693558
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
posted
Q fever, btw, is notorious for causing a post infectious syndrome which in some cases is due to persistent infection.
Posts: 523 | From Stillwater,OK,USA | Registered: Sep 2004
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/
UBBFriend: Email this page to someone!
Printer-friendly view of this topic