posted
Hi -- I heard from someone today at our health expo that they're using TKO Orange on their dog and in their yard as a natural nontoxic tick control.
TKO Orange is a concentrate made from d'limonene, the natural insecticide in orange peels. A few drops are put in water and you can spray or mist whatever. I've used it for bug control and as a cleaner. I'm told it can also be used on clothing and skin.
Has anyone here used it as a tick control?
Posts: 13116 | From San Francisco | Registered: May 2006
| IP: Logged |
Tincup
Honored Contributor (10K+ posts)
Member # 5829
posted
Good morning Robin...
In my never ending quest to stay "green"... NOT Lyme green.. the other one.... I have purchased a number of orange peel based products, especially here in Florida.
My original purchase WAS years ago when they first came out. I would hope they have improved them since.. because some of them actually ate through their plastic containers.. needless to say... making a BIG mess.
However.. what I used worked well on many things and the smell was MUCH nicer than the chemical things used more often today.
I have not tried it for bug control in the yard though. Could work? I do have a couple of concerns though.. and this may totally be my imagination running wild.... but...
Could the product.. being a more "natural" thing made basically from a food product... possibly be something that would attract other bugs with the sweet orange smell?
Bees, roaches, ants, fireants, hornets, etc???
I absolutely don't know. Just something to consider before wide spread use maybe?
I also am a bit concerned that it seems to be very strong... as it ate through plastic.... so would having it on your skin be a problem in any way? I see you mentioned using just a few drops.. which makes me feel better about it.
HA! I actually just got a picture in my mind just now of washing my clothes in it to keep ticks away... then going out for a long walk and having a bunch of bees chasing me around cause they love that orange smell.
I wish I had an answer.. and hope maybe others have one because I would be interested.
I loved the product.. just sorry it ate through the container and left such a mess.
posted
Ok, I spoke again with the TKO Orange folks at the health expo yesterday.
They said it will not attract insects. It is an insect repellant. It would probably kill the insects that came in contact with it.
They said the concentrate could eat through plastic, but they are recommending drops in water for dilution.
Then one guy went ahead and rubbed the concentrate on his hands! When I expressed surprise, he said he had toughened hands. I think diluted would be better for contact!
So, it could be used on animals(the woman I spoke to rubs it on her dog), clothing, skin, kids, the yard(she uses the product on her yard), make the camping area safer, etc. Only caveat -- if someone is allergic to citrus.
By the way, TKO Orange also is a fantastic cleaner.
Discussion???
Posts: 13116 | From San Francisco | Registered: May 2006
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Thanks for posting I have given this volitile oils some thought insects deffinatly donot like them.
We use a version of it here at forestry it is hand mixed has white vinegar 1/2cup oil, of clove 6 drops, oil of eucalyptus 10 drops, oil of camphore 10 drops, 1/2cup water, 1cup skin so soft, shake well and spray on skin and clothing but it has to be refreshed every 2hrs and it makes you slimey and vinegary smelling.You can order all of these from phamacy.
See the oils? I think I will mention this to some of my cohorts and maybe add it in {d'limonene} to the mix maybe it will increase its effectiveness times. From link
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Types
Hemiterpenes consist of a single isoprene unit. Isoprene itself is considered the only hemiterpene, but oxygen-containing derivatives such as prenol and isovaleric acid are hemiterpenoids.
Monoterpenes consist of two isoprene units and have the molecular formula C10H16 YooHooo Marnie womp there it is!!!. Examples of monoterpenes are: geraniol and limonene.
Sesquiterpenes consist of three isoprene units and have the molecular formula C15H24. Examples of sesquiterpenes are: farnesol . The sesqui- prefix means one and a half.
Diterpenes are composed for four isoprene units and have the molecular formula C20H32. They derive from geranylgeranyl pyrophosphate . Examples of diterpenes are cembrene and taxadiene (precursor of taxol ). Diterpenes also form the basis for biologically important compounds such as retinal , retinal , and phytol .
Sesterterpenes, terpenes having 25 carbons and five isoprene units, are rare relative to the other sizes. The sester- prefix means half to three, i.e. two and a half.
Triterpenes consist of six isoprene units and have the molecular formula C30H48. The linear triterpene squalene , the major constituent of shark liver oil , is derived from the reductive coupling of two molecules of farnesyl pyrophosphate. Squalene is then processed biosynthetically to generate either lanosterol or cycloartenol , the structural precursors to all the steroids .
Tetraterpenes contain eight isoprene units and have the molecular formula C40H56. Biologically important tetraterpenes include the acyclic lycopene , the monocyclic gamma-carotene , and the bicyclic alpha- and beta-carotenes .
Polyterpenes consist of long chains of many isoprene units. Natural rubber consists of polyisoprene in which the double bonds are cis . Some plants produce a polyisoprene with trans double bonds, known as gutta-percha .
Geraniol, also called rhodinol, is a monoterpenoid and an alcohol. It is the primary part of oil-of-rose and palmarosa oil. It also occurs in small quantities in geranium, lemon, citronella, and many other essential oils. It appears as a clear to pale-yellow oil which is insoluble in water, but soluble in most common organic solvents. It has a rose-like odor, for which it is commonly used in perfumes. It is used in flavors such as peach, raspberry, grapefruit, red apple, plum, lime, orange, lemon, watermelon, pineapple and blueberry.
An alternate application has been found in the use of insect repellents or deterrants. Though it may repel mosquitoes, flies, lice, cockroaches, ants, and ticks, it is also produced by the scent glands of honey bees to help them mark nectar-bearing flowers and locate the entrances to their hives. Extensive testing by Dr. Je**y Bu*ler at the University of Florida has shown geraniol to be one of nature's most effective insect repellents.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Terpenoid
The terpenoids, sometimes referred to as isoprenoids, are a large and diverse class of naturally occurring organic chemicals similar to terpenes, derived from five-carbon isoprene units assembled and modified in thousands of ways. Most are multicyclic structures which differ from one another not only in functional groups, but also in their basic carbon skeletons. These lipids can be found in all classes of living things, and are the largest group of natural products. Plant terpenoids are extensively used for their aromatic qualities.
They play a role in traditional herbal remedies and are under investigation for antibacterial, antineoplastic and other pharmaceutical effects. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves and ginger and the color of yellow flowers. Well-known terpenoids include citral, menthol, camphor and the cannabinoids found in the Cannabis plant.
The steroids and sterols in animals are biologically produced from terpenoid precursors. Sometimes terpenoids are added to proteins, e.g. to enhance their attachment to the cell membrane; this is known as isoprenylation.
Structure and classification
Terpenes are hydrocarbons resulting from the combination of several isoprene units. Terpenoids can be thought of as modified terpenes, where methyl groups have been moved or removed, or oxygen atoms added. (Some authors use the term "terpene" more broadly, to include the terpenoids.) Just like terpenes, the terpenoids can be classified according to the number of isoprene units used: � Monoterpenoids, 2 isoprene units � Sesquiterpenoids, 3 isoprene units � Diterpenoids, 4 isoprene units � Sesterterpenoids, 5 isoprene units � Triterpenoids, 6 isoprene units � Tetraterpenoids, 8 isoprene units � Polyterpenoids with a larger number of isoprene units Terpenoids can also be classified according to the number of cyclic structures they contain. Biosynthesis There are two metabolic pathways of creating terpenoids:
Mevalonic acid pathway Many organisms manufacture terpenoids through the HMG-CoA reductase pathway, the pathway that also produces cholesterol. The reactions take place in the cytosol. The pathway was discovered in the 1950s.
MEP/DOXP pathway The 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate pathway (MEP/DOXP pathway), also known as non-mevalonate pathway or mevalonic acid independent pathway, takes place in the plastids of plants and apicomplexan protozoa as well as in many bacteria. It was discovered in the late 1980s.
Pyruvate and glyceraldehyde 3-phosphate are converted by DOXP synthase (Dxs) to 1-deoxy-D-xylulose 5-phosphate, and by DOXP reductase (Dxr, IspC) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
The subsequent three reaction steps catalyzed by 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase (YgbP, IspD), 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (YchB, IspE), and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (YgbB, IspF) mediate the formation of 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate (MEcPP). Finally, MEcPP is converted to (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMB-PP) by HMB-PP synthase (GcpE, IspG), and HMB-PP is converted to isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) by HMB-PP reductase (LytB, IspH).
IPP and DMAPP are the end products in either pathway, and are the precursors of isoprene, monoterpenoids (10-carbon), diterpenoids (20-carbon), carotenoids (40-carbon), chlorophylls and plastoquinone-9 (45-carbon). Synthesis of all higher terpenoids proceeds via formation of geranyl pyrophosphate (GPP), farnesyl pyrophosphate (FPP), and geranylgeranyl pyrophosphate (GGPP).
Although both pathways, MVA and MEP, are mutually exclusive in most organisms, interactions between them have been reported in plants and few bacteria species.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Turpentine
Any resinous exudate or extract from conifers, especially pines; now also commonly a term for its volatile fraction, oil (or spirits) of turpentine. Semifluid mixtures of organic compounds consisting of resins dissolved in a volatile oil, turpentines can be distilled (see distillation) into the volatile oil of turpentine and the nonvolatile rosin.
The oil, a mixture of monoterpenes (see isoprenoid), chiefly pinene, is a colourless, odorous, flammable liquid that does not mix with water but is a good solvent for many substances.
Oil of turpentine is favoured over petroleum solvents as an oil-paint thinner, varnish solvent, and brush cleaner. Its chief use is now as a raw material for resins, insecticides, oil additives, and synthetic pine oil and camphor and as a solvent.
A thin volatile essential oil, C10H16, obtained by steam distillation or other means from the wood or exudate of certain pine trees and used as a paint thinner, solvent, and medicinally as a liniment. Also called oil of turpentine, spirit of turpentine.
The sticky mixture of resin and volatile oil from which turpentine is distilled. A brownish-yellow resinous liquid obtained from the terebinth. To extract turpentine from (a tree).
Isoprenoid
Class of organic compounds made up of two or more structural units derived from isoprene. Isoprene is a five-carbon hydrocarbon with a branched-chain structure, two double bonds (see bonding), and the molecular formula C5H8.
In isoprenoids, isoprene units (with one or neither of their double bonds) are linked into larger molecules having from two to thousands of five-carbon units that can take the form of both linear structures and rings.
Many of these molecules play a wide variety of roles in plant and animal physiological processes and as intermediates in the biological synthesis of other important molecules.
They contribute greatly to the flavours and fragrances of essential oils and other plant-derived substances. Geraniol (a contributor to rose perfumes; from geranium oil), menthol (from peppermint oilagain see pepperment post), citral (from lemongrass oil), limonene (from lemon and orange oils), pinene (from turpentine), and camphor each have two isoprene units.
Examples with more units include phytol, a precursor of chlorophyll; squalene, the precursor of cholesterol and other steroids; lycopene, the red pigment in tomatoes and an important phytochemical; and carotene, the pigment in carrots and a precursor of vitamin A. Natural rubber and the related gutta-percha are polyisoprenes comprising many thousands of isoprene units.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Discussion Antibiotic resistance in virtually all pathogenic bacteria now constitutes a major public health hazard worldwide and creates an urgent need for novel anti-infective strategies.
A large fraction of eubacteria including many serious human pathogens, for example the food-borne Campylobacter jejuni which causes gastroenteritis [35,36], use exclusively the nonmevalonate pathway for the biosynthesis of terpenoids,and the enzymes of the pathway are essential for their survival [18,37,38].
Because these enzymes do not occur in vertebrates, they are attractive therapeutic targets. It should also be noted that the malaria causing Plasmodium species use the nonmevalonate pathway exclusively and can be treated with fosmidomycin, an inhibitor of 2C methyl- D-erythritol 4-phosphate synthase [25,26].
Clustering of ispD and ispF genes has been reported earlier and has played an important role in the elucidation of the nonmevalonate pathway [14,16]. A detailed analysis of sequence similarity and topology of the ispD and ispF genes afforded the dendrogram in Fig. 7. Remarkably, all a- and e-proteobacteria studied feature bifunctional IspDF enzymes.
However, bifunctional enzymes are not a unique feature of proteobacteria and are also found in the genetically distant Spirochetes. The putative bifunctional IspDF enzymes have not been studied previously in any detail.
We chose the enzyme from the human pathogen for the present study with the expectation that information on nonmevalonate pathway enzymes from human pathogens may serve as the basis for antibiotic development.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
posted
Up for more folks to read, plus thx, Tree, looks very interesting, I will read it all later...
Posts: 13116 | From San Francisco | Registered: May 2006
| IP: Logged |
posted
Up. I hope you all are reading this post, because this may be a nontoxic rick repellant solution. TKO Orange is sold in stores I believe in diluted form, and also in concentrate form from online business ordering.
Posts: 13116 | From San Francisco | Registered: May 2006
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Essential oils:MONOTERPENES: Many monoterpenes possess antitumor activity in animal and cell models. They have also antioxidant properties, g-terpene being one of the most effective.
� Agar oil, distilled from Agarwood (Aquilaria malaccensis). Highly prized for its fragrance.[2] � Ajwain oil, distilled from the leaves of Bishop's weed (Carum Copticum). Oil contains 35-60% thymol. [3] � Angelica root oil, distilled from the Angelica archangelica.[4] � Anise oil, from the Pimpinella anisum, rich odor of licorice, used medicinally.[5] � Balsam oil, from the Myroxylon pereirae.[6] � Basil oil is used in making perfumes, as well as in aromatherapy � Bergamot oil, used in aromatherapy and in perfumes. � Black Pepper essential oil is distilled from the berries of Piper nigrum. � Buchu oil, made from the buchu shrub. Considered toxic and no longer widely used. Formerly used medicinally. � Cannabis flower essential oil, used as a flavoring in foods, primarily candy and beverages. Also used as a scent in perfumes, cosmetics, soaps, and candles. [7] � Caraway oil, used a flavoring in foods. Also used in mouthwashes, toothpastes, etc. as a flavoring agent. [8] � Cardamom seed oil, used in aromatherapy and other medicinal applications. Extracted from seeds of subspecies of Zingiberaceae (ginger). Also used as a fragrance in soaps, perfumes, etc. [9] � Carrot seed oil (essential oil), used in aromatherapy. � Cedarwood oil, primarily used in perfumes and fragrances. [10] � Chamomile oil, used medicinally and in aromatherapy. � Cinnamon oil, used for flavoring. � Cistus � Citronella oil, from a plant related to lemon grass is used as an insect repellent, as well as medicinally. � Clary Sage � Clove leaf oil, used as a topical anesthetic to relieve dental pain. � Coriander � Costmary oil (bible leaf oil), from the Tanacetum balsamita[11] [12] � Cranberry seed oil, equally high in omega-3 omega-6 fatty acids, primarily used in the cosmetic industry. � Cumin oil/Black seed oil, used as a flavor, particularly in meat products. Also used in veterinary medicine. � Cypress � Davana oil, from the Artemisia pallens, used as a perfume ingredient and as a germicide.[13] � Dill oil, chemically almost identical to caraway seed oil. High carvone content. � Eucalyptus oil, historically used as a germicide. Commonly used in cough medicine, among other medicinal uses. [14] � Fennel seed oil, used medicinally, particularly for treating colic in infants. � Fenugreek oil, used medicinally and for cosmetics from ancient times. � Fir � Frankincense oil, used for aromatherapy and in perfumes. � Galbanum � Geranium oil, used medicinally, particularly in aromatherapy. � Ginger oil, used medicinally in many cultures. � Goldenrod � Grapefruit oil, extracted from the peel of the fruit. Used in aromatherapy. Contains 90% limonene. [15] � Henna oil, used medicinally. [16] � Helichrysum � Hyssop � Idaho Tansy � Jasmine oil, used for its flowery fragrance. � Juniper berry oil, used as a flavor. Also used medicinally, including traditional medicine.
Lavender oil is distilled from the lavender flower � Laurus nobilis � Lavender oil, used primarily as a fragrance. Also used medicinally. [17] � Ledum � Lemon oil, similar in fragrance to the fruit. Unlike other essential oils, lemon oil is usually cold pressed. Used medicinally, as an antiseptic, and in cosmetics.[18] � Lemongrass � Litsea cubeba oil, lemon-like scent, often used in perfumes and aromatherapy. � Marjoram � Melaleuca See Tea tree oil � Melissa oil (Lemon balm), sweet smelling oil used primarily medicinally, particularly in aromatherapy. � Mentha arvensis oil/Mint oil, used in flavoring toothpastes, mouthwashes and pharmaceuticals, as well as in aromatherapy and other medicinal applications. [19] � Mountain Savory � Mugwort oil, used in ancient times for medicinal and magical purposes. Currently considered to be a neurotoxin. [20] � Mustard oil (essential oil), containing a high percentage of allyl isothiocyanate or other isothiocyanates, depending on the species of mustard � Myrrh oil, warm, slightly musty smell. Used medicinally. � Myrtle � Nutmeg � Orange oil, like lemon oil, cold pressed rather than distilled. Consists of 90% d-Limonene. Used as a fragrance, in cleaning products and in flavoring foods.[21] � Oregano oil, contains thymol and carvacrol, making it a useful fungicide. Also used to treat digestive problems. [22] � Orris oil is extracted from the roots of the Florentine iris (Iris florentina) and used as a flavouring agent, in perfume, and medicinally.[23] � Palo Santo � Parsley oil, used in soaps, detergents, colognes, cosmetics and perfumes, especially men's fragrances. [24] � Patchouli oil, very common ingredient in perfumes. � Perilla essential oil, extracted from the leaves of the perilla plant. Contains about 50-60% perillaldehyde. � Pennyroyal oil, highly toxic. An abortifacient and can even in small quantities cause acute liver and lung damage. [25] � Peppermint oil, used in a wide variety of medicinal applications. � Petitgrain � Pine oil, used as a disinfectant, and in aromatherapy. � Ravensara � Red Cedar � Roman Chamomile � Rose oil, distilled from rose petals, Used primarily as a fragrance. � Rosehip oil, distilled from the seeds of the Rosa rubiginosa or Rosa Mosqueta. Used medicinally. � Rosemary oil, distilled from the flowers of Rosmarinus officinalis. Used in aromatherapy, topically to sooth muscles, and medicinal for its antibacterial and antifungal properties. [26] � Rosewood oil, used primarily for skin care applications. Also used medicinally. � Sage oil, used medicinally.
The spice star anise is distilled to make star anise oil � Sandalwood oil, used primarily as a fragrance, for its pleasant, woody fragrance.[27] � Sassafras oil, from sassafras root bark. Used in aromatherapy, soap-making, perfumes, and the like. Formerly used as a spice, and as the primary flavoring of root beer, inter alia. � Savory oil, from Satureja species. Used in aromatherapy, cosmetic and soap-making applications. � Schisandra oil, from the Schisandra chinensis, used medicinally. [28] � Spearmint oil, often used in flavoring mouthwash and chewing gum, among other applications.[29] � Spikenard � Spruce � Star anise oil, highly fragrant oil using in cooking. Also used in perfumery and soaps, has been used in toothpastes, mouthwashes, and skin creams.[30] 90% of the world's star anise crop is used in the manufacture of Tamiflu, a drug used to treat avian flu � Tangerine � Tarragon oil, distilled from Artemisia dracunculus, used medicinally. � Tea tree oil, distilled from Melaleuca alternifolia, used medicinally. � Thyme oil, used medicinally. � Tsuga � Valerian � Vetiver oil (khus oil) a thick, amber oil, primarily from India. Used as a fixative in perfumery, and in aromatherapy. � Western red cedar � Wintergreen � Yarrow oil is used medicinally, to relieve joint pain � Ylang-ylang
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
J Med Entomol. 2005 May ;42 (3):352-8 15962787 Use of novel compounds for pest control: insecticidal and acaricidal activity of essential oil components from heartwood of Alaska yellow cedar.
[My paper] Nicholas A Panella , Marc C Dolan , Joseph J Karchesy , Yeping Xiong , Javier Peralta-Cruz , Mohammad Khasawneh , John A Montenieri , Gary O Maupin
Laboratory bioassays were conducted to determine the activity of 15 natural products isolated from essential oil components extracted from the heartwood of Alaska yellow cedar, Chamaecyparis nootkatensis (D. Don) Spach., against Ixodes scapularis Say nymphs, Xenopsylla cheopis (Rothchild), and Aedes aegypti (L.) adults.
Four of the compounds from the essential oil have been identified as monoterpenes, five as eremophilane sesquiterpenes, five as eremophilane sesquiterpene derivatives from valencene and nootkatone, and one as a sesquiterpene outside the eremophilane parent group.
Carvacrol was the only monoterpene that demonstrated biocidal activity against ticks, fleas, and mosquitoes with LC50 values after 24 h of 0.0068, 0.0059, and 0.0051% (wt:vol), respectively.
Nootkatone from Alaska yellow cedar was the most effective of the eremophilane sesquiterpenes against ticks (LC50 = 0.0029%), whereas the nootkatone grapefruit extract exhibited the greatest biocidal activity against fleas (LC50 = 0.0029%).
Mosquitoes were most susceptible to one of the derivatives of valencene, valencene-13-aldehyde (LC50 = 0.0024%), after 24 h. Bioassays to determine residual activity of the most effective products were conducted at 1, 2, 4, and 6 wk after initial treatment.
Residual LC50 values for nootkatone did not differ significantly at 4 wk posttreatment from the observations made at the initial 24-h treatment.
The ability of these natural products to kill arthropods at relatively low concentrations represents an alternative to the use of synthetic pesticides for control of disease vectors.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
We have surveyed the protein-folds in T. pallidum and B.burgdorferi. We have found that they have few unique folds, and the NTP hydrolase fold is the most common fold.
We have also studied the glucose and lipid metabolism in spirochetes. We have performed flux analyses on these two pathways. Our results show that in absence of fatty acid biosynthesis pathway, metabolic flux in T.pallidum and B. burgdorferi is constrained and is distributed disproportionately in favor of glycolytic pathway.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
posted
Hi Tree - could you explain the meaning of that last bit about absence of fatty acid synthesis and metabolic glycolytic pathway? Thx.
Posts: 13116 | From San Francisco | Registered: May 2006
| IP: Logged |
cactus
Frequent Contributor (1K+ posts)
Member # 7347
posted
I've been interested in this topic as well.
Tree, that is all great info - I hope my feeble Mepron brain can decipher it soon, right now it looks like another language.
I would be really interested in knowing if this is safe to use on kids' clothing, or in a yard where kids will be playing... Any thoughts on that, Robin or Tree?
Thanks, Cactus
-------------------- �Did you ever stop to think, and forget to start again?� - A.A. Milne Posts: 1987 | From No. VA | Registered: May 2005
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Image below is different types of protien Folds
First is this #1 Metabolic flux refers to the rate of flow of metabolites along a metabolic pathway, or even through a single enzyme. A calculation may also be made of carbon (or other elements, e.g. nitrogen) flux. It is dependent on a number of factors,
including: enzyme concentration; the concentration of precursor, product, and intermediate metabolites; post-translational modification of enzymes; and the presence of metabolic activators or repressors. Metabolic control analysis and flux balance analysis provide frameworks for understanding metabolic fluxes and their constraints.
So Our results show that in absence of fatty acid biosynthesis pathway {{{No fatty acid path working}}}, metabolic flux #1 in T.pallidum and B. burgdorferi is {{constrained Held back not working}} and is distributed disproportionately in favor of glycolytic pathway {{its prefferring to use the glycolytic path way to do its thing}}.
Glycolysis {= glycolytic pathway }is a metabolic pathway by which a 6-carbon glucose (Glc) molecule is oxidized to two molecules of pyruvic acid (Pyr). The word glycolysis is derived from Greek γλυκύς (sweet) and λύσις (rupture). It is the initial process of most carbohydrate catabolism, and it serves three principal functions:
In biochemistry, a hydrolase is an enzyme that catalyzes the hydrolysis of a chemical bond.{{Makes two get together}}
In other words it using carbohydrate's glucose ie sugar for its function and life building needs its energy . When fatty acids are not around.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Yeast problem check this out
J Agric Food Chem, 2004 Jun 16, 52(12), 3911 - 4 Chemical composition and antimicrobial activity of the essential oils from the gum of Turkish pistachio (Pistacia vera L.); Alma MH et al.; The essential oil from the gum of Pistachio (Pistacia vera L . (Anacardiaceae)) grown in Turkey was obtained by the hydro-distillation method, and its chemical composition was analyzed by GC and GC-MS . Moreover, the antimicrobial activities of the oil against the growth of 13 bacteria and 3 pathogenic yeasts were evaluated using the agar-disk diffusion and minimum inhibitory concentration (MIC) methods . The results showed that the essential oil contained about 89.67% monoterpenes, 8.1% oxygenated monoterpenes and 1.2% diterpenes . alpha-Pinene (75.6%), beta-pinene (9.5%), trans-verbenol (3.0%), camphene (1.4%), trans-pinocarveol (about 1.20%), and limonene (1.0%) were the major components . The antimicrobial results showed that the oil inhibited nine bacteria and all the yeasts studied, and the activities were considerably dependent upon concentration and its bioactive compounds such as carvacrol, camphene, and limonene . Moreover, the essential oil of the gum was found to be more effective yeastcide than Nystatin, synthetic yeastcide.
Now we cant have it all no cake and eat it
Furthermore, the antibacterial activities of the oil were lower than those of standard antibiotics {{{bummer}}}, ampicillin sodium, and streptomycine sulfate under the conditions studied.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
up for a look
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
quote:Originally posted by treepatrol: up for a look
up
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
upcy
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
up Limonene->Molecular formula C10H16
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
posted
Hi Tree - I see you bumped up TKO Orange today.
So I'd like to reiterate that it's the clothing tick repellent I use - you can get it in concentrate form from the company or it's sold in a somewhat diluted form as Orange Guard in hardware stores and healthfood stores.
I put a couple drops of the concentrate in a spray bottle and fill it up with water. It's good for clothing but I find that it stings my skin, so I don't use it there. It dries quickly.
Ok for all except if you're allergic to citrus or you're a cat.
If you spray it on any bug, it melts their exoskeleton and kills them instantly. Good for any bug problem in the home.
I think it could be used for wide application, meaning spray your camping equipment, sitting blanket, etc when outside. It's biodegradable - I would assume 24 hours effectiveness inside the house.
It's also a fantastic cleaner - gets spots out, gets any mold. When my premises were exposed to fumes from a fire, two restoration companies could only offer toxic chemicals for clean-up. Spraying TKO Orange on my walls rescued them from the fire smell and chemicals.
Posts: 13116 | From San Francisco | Registered: May 2006
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Hi Robin and thanks!!
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
up for james
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
up
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
posted
Don't use orange or any other essential/botanical oil on cats. They are toxic. Cats ingest everything that goes on their skin or fur.
Posts: 386 | From WA state | Registered: May 2005
| IP: Logged |
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/
UBBFriend: Email this page to someone!
![[Big Grin]](biggrin.gif)
![[confused]](graemlins/confused.gif)
![[Cool]](cool.gif)
Ok, I spoke again with the TKO Orange folks at the health expo yesterday. 
Printer-friendly view of this topic