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» LymeNet Flash » Questions and Discussion » Medical Questions » The Pathogenesis of Lyme Neuroborreliosis - from Infection to Inflammation

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Author Topic: The Pathogenesis of Lyme Neuroborreliosis - from Infection to Inflammation
listenswithcare
LymeNet Contributor
Member # 10719

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http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18097481

OR

http://tinyurl.com/3yrpra

Posts: 276 | From Maryland | Registered: Dec 2006  |  IP: Logged | Report this post to a Moderator
scottie
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This is a great article - if you can understand it! But ultimately, what does it mean if one does have this inflammatory response - is there a way to overcome it?
Posts: 90 | From massachusetts | Registered: Aug 2006  |  IP: Logged | Report this post to a Moderator
nellypointis
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I don't think this is a great article at all.

It says lots of things which are highly debatable for eg it claims that in Europe meningitis and secondary EMs are rare to illustrate what they are saying re garinii disseminating via the nerves rather than via the blood. In my experience there are just as many cases of meningitis and of secondary EMs in Europe as in the US.

I think the underlying message in this article is that Borrelia in Europe leads to much milder illness (radiculitis, just a bit of pain along some nerves).

The concluding remark being:

"Therefore, further research on the pathophysiology of infection with B. b. would increase not only the knowledge of Lyme borreliosis Therefore, further research on the pathophysiology of infection with B. b. would increase not only the knowledge of Lyme borreliosis but also of other spirochetal diseases, with an increasing incidence and higher morbidity and mortality, like syphilis or Weil's syndrome"

Translate: Lyme is not a rare and not very serious illness but if we study it, we will learn about more frequent and more serious illnesses like syphilis or Weil's syndrome.

Nelly

Posts: 416 | From france | Registered: Oct 2001  |  IP: Logged | Report this post to a Moderator
   

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