LymeNet Home LymeNet Home Page LymeNet Flash Discussion LymeNet Support Group Database LymeNet Literature Library LymeNet Legal Resources LymeNet Medical & Scientific Abstract Database LymeNet Newsletter Home Page LymeNet Recommended Books LymeNet Tick Pictures Search The LymeNet Site LymeNet Links LymeNet Frequently Asked Questions About The Lyme Disease Network LymeNet Menu

LymeNet on Facebook

LymeNet on Twitter




The Lyme Disease Network receives a commission from Amazon.com for each purchase originating from this site.

When purchasing from Amazon.com, please
click here first.

Thank you.

LymeNet Flash Discussion
Dedicated to the Bachmann Family

LymeNet needs your help:
LymeNet 2020 fund drive


The Lyme Disease Network is a non-profit organization funded by individual donations.

LymeNet Flash Post New Topic  New Poll  Post A Reply
my profile | directory login | register | search | faq | forum home

  next oldest topic   next newest topic
» LymeNet Flash » Questions and Discussion » Medical Questions » false pos through igenex

 - UBBFriend: Email this page to someone!    
Author Topic: false pos through igenex
big lenny
LymeNet Contributor
Member # 3048

Icon 1 posted      Profile for big lenny     Send New Private Message       Edit/Delete Post   Reply With Quote 
has anyone ever had a false positive through igenex labs?
Posts: 259 | From new york | Registered: Sep 2002  |  IP: Logged | Report this post to a Moderator
1Bitten2XShy
Unregistered


Icon 1 posted            Edit/Delete Post   Reply With Quote 
How is one to know they have a false positive? Lyme imitates so many other things...not really sure you could tell you have a "false positive".
IP: Logged | Report this post to a Moderator
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136

Icon 1 posted      Profile for CaliforniaLyme     Send New Private Message       Edit/Delete Post   Reply With Quote 
it is common for mainstream docs to call ANY Lyme positive a false positive because they are idiots when it comes to TBDs. No offense*)!

And WELCOME to LymeNet*)!!!!!!!!!
!*)!*)*!)!*)!*)!*)!*)!*)!

--------------------
There is no wealth but life.
-John Ruskin

All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer

Posts: 5639 | From Aptos CA USA | Registered: Apr 2005  |  IP: Logged | Report this post to a Moderator
SForsgren
Frequent Contributor (1K+ posts)
Member # 7686

Icon 1 posted      Profile for SForsgren         Edit/Delete Post   Reply With Quote 
It is POSSIBLE, though not likely. If you did a standard Western Blot and want to confirm further, IGeneX has a 30/31 confirmation test that may provide more validation of the result. You may want to contact them to discuss.

--------------------
Be well,
Scott

Posts: 4617 | From San Jose, CA | Registered: Jul 2005  |  IP: Logged | Report this post to a Moderator
randibear
Honored Contributor (10K+ posts)
Member # 11290

Icon 1 posted      Profile for randibear     Send New Private Message       Edit/Delete Post   Reply With Quote 
i've never heard of igenex getting a false positive. they're supposed to be the best....

--------------------
do not look back when the only course is forward

Posts: 12262 | From texas | Registered: Mar 2007  |  IP: Logged | Report this post to a Moderator
improver
LymeNet Contributor
Member # 8380

Icon 1 posted      Profile for improver     Send New Private Message       Edit/Delete Post   Reply With Quote 
I keep running into this problem. Regular doctors have told some people that their Igenex results must be a false positive. My question then is what do they have that these doctors cannot find, that makes them produce these antibodies and have these symptoms ????
Posts: 413 | From nj | Registered: Nov 2005  |  IP: Logged | Report this post to a Moderator
asus
LymeNet Contributor
Member # 13881

Icon 1 posted      Profile for asus     Send New Private Message       Edit/Delete Post   Reply With Quote 
I suppose a test could be called a "false positive" if someone who met the criteria for a positive test had no reaction whatsoever to a trial of treatment. That is, they had no herx, no improvement, etc...

It would be interesting for IGENEX to track response to treatment according to their positive results. Essentially to test the ability of their supposedly "less strict" criteria to predict clinical response.

There have been Lyme doctors who have claimed that anyone with a single lyme specific band and lyme symptoms is something like 90% likely to respond to lyme treatment... I have not seen this actually published anywhere, so I don't know the accuracy of the statement...

Posts: 116 | From Ann Arbor, MI | Registered: Nov 2007  |  IP: Logged | Report this post to a Moderator
Michelle M
Frequent Contributor (1K+ posts)
Member # 7200

Icon 1 posted      Profile for Michelle M   Author's Homepage     Send New Private Message       Edit/Delete Post   Reply With Quote 
From ILADS research:

"Engstrom et al.2 and Aguero-Rosenfeld et al.3,4 confirmed that almost one-third of all Lyme patients are IgG negative during the first year.

Two years after a physician-diagnosed EM, 45% of the patients were negative by ELISA. In another study, Aguero-Rosenfeld et al. showed that the ELISA response declined much more rapidly than the Western blot response.4

Their study also demonstrated that the two-step protocol of the CDC/ASPHLD criteria would fail to confirm infection in some patients with culture-proven EM. Furthermore, although a majority (89%) of patients with the EM rash developed IgG antibodies by Western blot sometime during disease, only 22% were positive by the criteria of the CDC/ASPHLD.4

The Engstrom et al. study did not use the IgG blot criteria of the CDC/ASPHLD.2 They found that 2 of 5 bands gave them a specificity of 93 to 96% and a sensitivity of 100% in the 70% of patients that produced antibody. This could imply an even lower sensitivity would be obtained had the more stringent CDC/ASPHLD criteria been used as a guideline for laboratory screening."

Bottom line: "False positive" is a load of BS from doctors who do not understand lyme disease.

They fail to recognize that certain bands can only appear from lyme infection and nothing else.

They are quick to mock and belittle IGeneX due mainly to their own dogged adherence to the IDSA guidelines in order to save face.

Actual scientists, patients, and LLMD's know better.

The "claimed" false positives are because (a) they couldn't diagnose it correctly themselves or (b) they simply are too stupid to do some research, leaving patients to fend for themselves or suffer the consequences.

(But ask me how I REALLY feel!!!)

Michelle

Posts: 3193 | From Northern California | Registered: Apr 2005  |  IP: Logged | Report this post to a Moderator
bunnyfluff
LymeNet Contributor
Member # 14117

Icon 4 posted      Profile for bunnyfluff   Author's Homepage     Send New Private Message       Edit/Delete Post   Reply With Quote 
IMHO~ That would be like getting a "false positive" on a pregnancy test! Either you have the reactive proteins, or you DON'T, and you cannot possibly react to the test without it.

I had my Igenex test results with 9 positive + thingies (of course, CDC neg), and had to see a new pain management Dr., as mine moved to Denmark (!!), and the ignorant duck looked at the Igenex results and said "what would make you think you have Lyme??"

I said "the positive test results", and she said (and this still makes me mad) "It says CDC neg.", and she attempted to give me meds for Fibromyalgia! I said "I don't have FMS (moron)" [tsk]

Whatever!!

Bunny

--------------------
4 strong winds that blow lonely,
7 seas that run high.

All those things that don't change
Come what may.

Posts: 103 | From Dallas/ Fort Worth. TX | Registered: Dec 2007  |  IP: Logged | Report this post to a Moderator
   

Quick Reply
Message:

HTML is not enabled.
UBB Code is enabled.

Instant Graemlins
   


Post New Topic  New Poll  Post A Reply Close Topic   Feature Topic   Move Topic   Delete Topic next oldest topic   next newest topic
 - Printer-friendly view of this topic
Hop To:


Contact Us | LymeNet home page | Privacy Statement

Powered by UBB.classic™ 6.7.3


The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:

The Lyme Disease Network of New Jersey
907 Pebble Creek Court, Pennington, NJ 08534 USA


| Flash Discussion | Support Groups | On-Line Library
Legal Resources | Medical Abstracts | Newsletter | Books
Pictures | Site Search | Links | Help/Questions
About LymeNet | Contact Us

© 1993-2020 The Lyme Disease Network of New Jersey, Inc.
All Rights Reserved.
Use of the LymeNet Site is subject to Terms and Conditions.