Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Find the PDE6D links.
What this enzyme can do...how it works. The interplay.
Review my info. on the WFL with relationship to hunting at night, rods in the eyes, cobalt, etc.
I think it MIGHT BE the "protective" enzyme in the blood of the WFL that is destroyed by heat.
Find, as I have the connections between cGMP, cAMP, PKC (inhibited by Bb) and PKG, glutamate, etc.
The CURE for Bb lies in a protein or enzyme in the blood of that lizard.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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Vermont_Lymie
Frequent Contributor (1K+ posts)
Member # 9780
posted
Marnie,
Good to see you here and still researching! Hope all is well.
I have NO idea what you are talking about here, as I have forgotten all the biochemistry learned years ago. So I will leave it for the serious researchers.
But I am happy to see that you are still hunting for a CURE. You go girl!
Posts: 2557 | From home | Registered: Aug 2006
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Your sister is lucky to have a loved one take such in interest in illness.
Of the things you have discovered,what has helped her the most along the way.
Thanks
Posts: 137 | From wethersfield ct | Registered: Mar 2006
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Steroid shots directly into her eyes halted uveitis which was leading to permanent eye damage and blindness. It is the inflammatory cytokines (esp. IL1 B) that are so damaging.
Humira helped reduce TNF alpha, but did not halt the joint destruction...which continues. Bone destruction happens faster than bone rebuilding.
Fosamax didn't work.
She could not tolerate Methotrexate.
See my new post today...keep in mind, in many locations of our body (eyes, joints, etc.), hyaluronic acid - HA- is normally present and needed...if it leaves those areas to be used for other things (like to bind to CD44)...
Sis is now dx'd "autoimmune".
We MUST identify that protein/enzyme in the blood of the WFL that leads to the disappearance of Bb.
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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