MSM, methylsulfonylmethane (METH-əl-sul-FON-il-METH-ane) provides sulfur, a vital building block of joints, cartilage, skin, hair and nails, and methyl groups, which support many vital biochemical processes in the body, including energy production.
MSM is a naturally-occurring nutrient found in small amounts of many foods. As a dietary supplement, MSM is synthesized.
When made correctly, it is identical to that found in nature. MSM can be taken alone or in combination with other joint health supplements, such as glucosamine and chondroitin.
Published, peer-reviewed clinical research in the U.S. has shown MSM is safe and effective in increasing joint comfort and supporting a normal range of motion.
A:The exact mechanisms of how MSM works are still being identified in ongoing scientific research.
However, scientific studies have now confirmed that MSM is a safe and effective anti-inflammatory agent.
It may also contribute to the integrity of joint cartilage and other connective tissue.
In recent animal research conducted in Japan, MSM was found to act as an immunomodulator, preventing the immune system from mounting dangerous autoimmune responses to noxious stimuli.
It also prevented local inflammation to a significant enough degree as to halt an autoimmune reaction at the genetic stage of induction.
It appears to affect autoimmune responses, such as the immune system's development of antibodies against its own tissues.
MSM has been shown to inhibit the development of abnormal antibodies to collagen, and to prevent production of rheumatoid factor and antinuclear antibodies (ANA).
Though the pain relieving properties of MSM are well known, mechanisms by which it accomplishes this are still under investigation.
MSM most likely inhibits inflammatory prostaglandins and leukotrienes, hormone-like substances that create inflammatory cascades in the body associated with pain production.
MSM's effects on connective tissue are also well known.
It is presumed, though not proven, that the beneficial clinical effects noted in humans on skin, hair, nails, and joint cartilage (as well as on hooves and coats in animals) has to do with MSM's sulfur content.
Sulfur is abundant in connective tissue, and sulfur depletion in connective tissue is known to lead to problems.
Because MSM is 34% sulfur, it is likely that the integrity of connective tissue is enhanced with MSM supplementation.
MSM's benefits are those of a dietary supplement.
It should not be used to treat serious diseases unless under the supervision of a medical doctor.
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Sounds good... anyone taking it?
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sparkle7
Frequent Contributor (5K+ posts)
Member # 10397
There are several dietary supplements that help reduce inflammation: MSM, Salmon oil, Aflamend�, and Lyprinol� work well.
MSM, Methylsulfonylmenthane (MSM) is a very safe supplement that is used to reduce inflammation without the risk of any side effects.
It is inexpensive, but therapeutic doses for an adult are high.
Salmon oil is abundantly rich in the Omega-3 fatty acids.
The fatty acids EPA and DHA that are found in Salmon oil help reduce inflammation and have many other health benefits.
Aflamend� is a blend of herbal extracts I designed to help reduce inflammation.
Aflamend� augments the health benefits of Dr. Taylor's "Remedi for Healthy Living" program by improving insulin sensitivity and enhancing a healthy fatty acid metabolism, both of which reduce chronic inflammation.
Lyprinol,� a specific stabilized extract of green lipped mussels, is a relatively new supplement for inflammation.
Early feedback of Lyprinol� use is reporting several beneficial results for people with many stubborn inflammatory disorders.
This product is a unique fatty acid that is an effective tumor necrosis factor (TNF), lipoxygenase and (LOX) inhibitor.
Its potency to reduce inflammation is approximately 200 times stronger than fish oil.
It is also an effective MMP-9 inhibitor thus it helps reduce the MMPs that digest the extracellular matrix proteins of the body.
Other inhibitors of TNF include Boswellia, Quercetin, Cat's Claw, Turmeric, NAC (N-acetyl-cysteine).
Nettle also has the ability to inhibit the release of MMP triggered by BLPs.
Cherry Fruit extract, Cetyl Myristoleate, help inflammation problems.
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