Hoosiers51
Frequent Contributor (1K+ posts)
Member # 15759
posted
Is it grape seed extract or grapeFRUIT seed extract?
I just started taking a supplement with grape seed extract in it, as an antioxidant and to help my kidneys, and I feel like I'm sick just from detox. It is crazy. My urine also smells very strong, which I hope is a detox sign.
Posts: 4590 | From Midwest | Registered: Jun 2008
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disturbedme
Frequent Contributor (1K+ posts)
Member # 12346
posted
Not sure if the grape seed does anything... I know that grapefruit seed extract supposedly busts lyme cysts.
Again, it does make some people herx and doesn't make others herx at all. It didn't make me herx at all. I did notice that it helped me feel somewhat better though. I guess, as with anything, it can go either way since everything is different for everyone.
-------------------- One can never consent to creep when one feels an impulse to soar. ~ Helen Keller
My Lyme Story Posts: 2965 | From Land of Confusion (bitten in KS, moved to PA, now living in MD) | Registered: Jun 2007
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Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
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GRAPE SEED extract is very effective against candida and in many formulas for that.
A search on PubMed will bring more information and also perhaps see if this will, too: www.vrp.com - upper right search, scroll down from products to articles.
lymebytes
Frequent Contributor (1K+ posts)
Member # 11830
posted
Grape seed extract is a highly potent phyto-antioxidant, not a cyst buster.
GSE - Grapefruit seed extract is a cyst buster
The following article is from pubmed regarding the efficacy of GSE (Grapefruit seed extract) as a Bb and Cyst eliminator:
Grapefruit Seed Extract is a Powerful In Vitro Agent Against Motile and Cystic Forms of Borrelia burgdorferi Sensu Lato
Infection. 2007 Jun;35(3):206-8. Brorson O, Brorson SH.
Lyme borreliosis [1], caused by B. burgdorferi sensu lato, may lead to long-term tissue infection, which may be difficult to cure. The outcome of Lyme borreliosis is highly dependant on the antibiotic treatment [2]. The observation of the ability of B. burgdorferi sensu lato to convert (and reconvert) to cystic forms [3-5] may explain why the infection sometimes is persistent and reactivating.
Therefore, it might be important to eradicate all germative forms (not only the motile form) of the bacterium to obtain a proper treatment for Lyme borreliosis. Grapefruit-seed extract (GSE) contains bioactive flavenoids (e.g., hesperitin, resveratrol, and naringenin) and has been shown to possess anti-microbiological effect against bacteria and fungus [6,7]. Many studies indicate that GSE is a substance whose therapeutic effect ranks equal to or better than other known anti-bacterial agents.
Conclusion: The highest GSE concentrations made the bacteria and cysts disappear completely, leaving only small uncharacteristic fragments; at lower GSE-levels the membranes showed herniation and disruption, and the contents had leaked out. The MBC was strongly dependent on the length of the incubation. GSE was very active even for very short incubation times, in agreement with previous results [7].
The MBC obtained by DFM for the motile bacteria agreed well with the TEM results. Presence of GSE reduced the conversion from spirochetes to cysts when the susceptibility testing was performed in distilled water.
This study was performed in vitro and further studies are needed to demonstrate eventual effects in vivo. From our results it will be rational to test the hypothesis that a combination of GSE and antibiotics will be efficient in the treatment of resistant Lyme borreliosis.
Grape Seed Extract - Optimal Brain Function and Proanthocyanidins -
By James South, M.A.
Grape seed extract provides a rich source of proanthocyanidins, chemical cousins of the more well-known bioflavonoids.
Proanthocyanidins have special value for brain health for at least two reasons - their free radical-quenching antioxidant effects and their collagen-protecting effects.
In some test models, proanthocyanidins are 50 times more potent antioxidants than the two most famous antioxidants, vitamins C and E.
Sophisticated tests have shown proanthocyanidins to be powerful quenchers of the hydroxyl radical, the most damaging of all common free radicals, as well as lipid peroxides (rancid fats).
Proanthocyanidins have also been shown to markedly delay the onset of lipid peroxidation and to effectively chelate iron ions.
Free iron ions are some of the most powerful promoters of lipid peroxide, hydrogen peroxide and hydroxyl radical production.1
This is a major contributor to the pathogenesis of Parkinsons disease, one of the most common neurological diseases of the aged.
The structure and function of the brain make it especially susceptible to free radical damage. Neurons are unusually rich in DHA (docosahexaenoic acid), the most polyunsaturated fat in the human body.
Greater polyunsaturation equals greater ease of free radical damage.
This damage is especially prone to occur to neuronal cell membranes - down which electric currents must pass - and to mitochondrial membranes, mitochondria being the power plants that generate the ATP energy that powers all aspects of our brains and bodies.
In the very act of burning food to liberate ATP energy in the mitochondria, electron sparks are released that promote free radical damage to polyunsaturate-rich mitochondrial membranes, the walls that cover and define the mitochondrial shape and structure.
Free radical-damaged mitochondria are poor energy producers; yet our brain neurons must collectively produce and use 20% of the bodys total ATP output. So,grape seed extract proanthocyanidins probably help brains gradually, over weeks to months, recover to the higher brain energy level needed to sustain mental focus and concentration.
- MUCH more to this article at link above.
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AND MANY more articles through the search at www.vrp.com
This group does sell supplements. Still, I find their research to be very extensive and always offers a wide range of expert citations for their research.
Hoosiers51
Frequent Contributor (1K+ posts)
Member # 15759
posted
I suppose this supplement (grape seed extract) could make me Herx from killing off yeast?
Ever since I took my first dose on Tuesday, I have felt soooo fatigued. It could be due to something else, but I am pretty sure it is causing the fatigue. Would the strange smell of my urine since starting this be a detox sign as well?
Posts: 4590 | From Midwest | Registered: Jun 2008
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posted
Grape seed extract is a vasodilator so if you have problems with low blood pressure or dysautonomia issues, it will make you feel worse. It always flattens me as does anything that is a vasodilator so you're tiredness may be due to that.
Best Wishes, bf
Posts: 191 | From Ontario | Registered: Feb 2006
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Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
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brf,
Thanks for your note. So much to remember and it helps to connect the dots.
Hoosiers51
Frequent Contributor (1K+ posts)
Member # 15759
posted
brf,
Thank you so much for letting me know....I have big time dysautonomia issues, so I bet that is it. The fatigue was also accompanied by extreme weakness. It happened within the hour of my first dose.
Too bad I can't take it, it sounds like a great supplement
And thank you for that additional info, Keebler....that helped further validate my decision to stop taking it. It explains a LOT though. Too bad.
Posts: 4590 | From Midwest | Registered: Jun 2008
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I've learned the hard way - I have a cupboard full of supplements that I can't use. I wondered why certain things kept backfiring on me when others were getting good results. Took me awhile through the brain fog to finally figure it out. Now whenever I hear of a new supplement or herbal I always google the name + vasodilator and see what comes up.
Sometimes, it also depends on the form. For instance, olive oil will flatten me right away while with olive leaf extract I just feel that old familiar brain drain - bearable to push through for a time.
Best Wishes, bf
Posts: 191 | From Ontario | Registered: Feb 2006
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Hoosiers51
Frequent Contributor (1K+ posts)
Member # 15759
posted
Great idea about googling the supplement with the word vasodilator!!!!
Were you saying that olive oil is a vasodilator?
Posts: 4590 | From Midwest | Registered: Jun 2008
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Don't you just love how these terms are tossed around! Vitamin E (alpha-tocopherol), carotenoids and phenolic compounds (simple phenols such as hydroxytyrosol and complex phenols such as oleuropein) are all antioxidants which have been shown to help prevent certain diseases and may also slow ageing.
The amount of phenolic compounds found in olive oil varies according to the climate of the growing area, when the olives are harvested, and how ripe they are when picked. Australian olive oil, like that used in redisland, is high in these valuable antioxidants.
The production and storage methods of olive oil also have an influence. Phenols have countless biological properties. For instance, hydroxytyrosol inhibits platelet aggregation and is anti-inflammatory. Oleuropein encourages the formation of nitric acid, which is a powerful vasodilator and exerts a strong antibacterial effect.
Posts: 191 | From Ontario | Registered: Feb 2006
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