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» LymeNet Flash » Questions and Discussion » Medical Questions » Borrelia Reproduction

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Author Topic: Borrelia Reproduction
kelmo
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http://bioweb.uwlax.edu/bio203/s2007/joyce_kait/life_historyreproduction.htm


Once in a host, B. burgdorferi reproduces asexually through mitosis
quote:
Mitosis, process in which a cell's nucleus replicates and divides in preparation for division of the cell. Mitosis results in two cells that are genetically identical, a necessary condition for the normal functioning of virtually all cells. Mitosis is vital for growth; for repair and replacement of damaged or worn out cells; and for asexual reproduction, or reproduction without eggs and sperm.
to make a colony. The species has not yet been found naturally outside of a host, and therefore it needs a host in order to reproduce. It has been known to spread into the blood, cerebrospinal fluid, heart, retina, brain, muscles, bone, spleen, liver, and brain (Schnarr, S., Franz, J., Krause, A., & Zeidler, H., 2006). While B. burgdorferi reproduces asexually through binary fission like most other bacterium, they also have an unique variations of reproduction. Sometimes a cyst forms in which young B. burgdorferi form and are later released. Also, buds may form on the lengthwise section of B. burgdorferi. These buds can eventually turn into cysts that contain growing B. burgdorferi and burst to release the bacterium. Additionally, B. burgdorferi is unique in its ability to reproduce essentially wherever and whenever it needs to while protecting itself from its hosts' immune system (Karlen, A., 2000).


We were discussing this on Lymechat. As you can see, there are no hatchlings involved.

It can go into a cyst "egg" form, and divide inside of the cyst, but the bacteria do not lay eggs.

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Lymeorsomething
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It's curious that they mention buds on the end of Bb because that is exactly how my floaters look. They look like spirochetes with bulbs at the end...

/\/\/\/\/\/O OK, bad depiction but you get the point...

I know many say you can't see the 'chetes but sometimes I wonder....

--------------------
"Whatever can go wrong will go wrong."

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AliG
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Oh no Kelmo! [puke]

I DIDN'T need to be reminded of this today! [shake]

It really looks pretty terrible when you lay it all out there like that. [Eek!]

Eggs?
Lay eggs?
Bacteria lay eggs?
HUH? [confused]

The LDA has a video clip of the little buggers conjugating. [dizzy]


[Frown]

--------------------
Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner.

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kelmo
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AliG, this is from my first post...please reread:

quote:
It can go into a cyst "egg" form, and divide inside of the cyst, but the bacteria do not lay eggs.
No eggs...no sex to create the eggs. Borrelia does not need a mate to reproduce.

The borrelia bacteria DIVIDE... mitosis

For a certain person here on the board who is continually seeing hatchlings in his microscope..it is not Lyme...or they are not hatchlings.

Kelmo

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Lymeorsomething
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Kelmo, can one see 'chetes as floaters or is this science fiction?

--------------------
"Whatever can go wrong will go wrong."

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lymie tony z
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I would hazzard a guess at saying NO one can not see spirochetes....

They are after all microscopic....so unless you're superguy or girl....

I don't believe it is possible to see microscopic organisims with the naked eye....

zman

--------------------
I am not a doctor...opinions expressed are from personal experiences only and should never be viewed as coming from a healthcare provider. zman

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brentb
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quote:
Originally posted by kelmo:


The borrelia bacteria DIVIDE... mitosis


Interesting stuff. We know borrelia exchange genetic material (have sex) frequently. So while it may not produce eggs it's still (one would assume) essential for it's continuity.

Try as I might I could not come up with a video of cell mitosis concerning borrelia. Does anyone know where one exist? I did find this video which purports the growth from bleb to full grown adult.
It's also not the first time I've read about this being the growth pattern.

http://technorati.com/videos/youtube.com%2Fwatch%3Fv%3D2YK_MsU0EPA

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Vermont_Lymie
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Thanks Kelmo for that explanation. The name of those mythical creatures, "lyme hatchlings" was getting to me too! Better than science fiction. [Smile]
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kelmo
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Vermont...I've missed you!
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Vermont_Lymie
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[hi] Hi Kelmo! Thanks, I've missed you (and lymenet) too!

Hope you are well and enjoying fall. I'm back to working full-time plus, thanks to two years of antibiotics. AND traveling much in the next month for work.

I am sorry that I will be very scarce on lymenet for the next month, though I hope to check in from time to time if I can figure out how to get on-line in some remote corners of the globe!!!! Take good care and please keep researching... I wish I had more time to do so [Smile]

[ 03. September 2008, 06:44 PM: Message edited by: Vermont_Lymie ]

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AliG
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I started working on this yesterday (before Brent posted) and got sidetracked. [bonk]

Hi Vermont! I'm glad you're back in action! [hi]

**************************

I understood your post Kelmo, I just didn't realize that someone actually thought there was egg-laying involved.

I re-read MY post & I can see why you thought I misunderstood your post. I was posting with a tone of "quizzical surprise" rather than [Eek!] on the "egg" thing.

The [Eek!] was just for the thought of them multiplying in ANY way shape or form. I hate to actually THINK about them multiplying.

Do they "hatch" out of the cysts when they have multiplied in there? Perhaps the person was thinking of cysts like eggs?

My LLMD had told me that he had actually seen them "mating". [puke]

I never really got into an in-depth conversation about it because I was having some really bad neuro Sx at the time & didn't really want to think about the little buggers "mating" in my brain. [Roll Eyes]

I have read that they exchange genetic material, what happens after that, I have no clue. I believe it somehow affects their virulence or survival abilities or something.

I haven't found ANY mention of Borrelia "EGGS" being laid anywhere. maybe the person is thinking of the Bb that emerge when the cysts burst. ????

******************

Hi Tony! [group hug]
Long time no see.
I hope all's been well with you and yours.
[hi]
Ali

--------------------
Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner.

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kelmo
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Sorry, AliG...I love ya, I didn't mean to sound like I was jumping all over you!

Please forgive me if it sounded that way.

Hey, I just noticed on another Lyme website that a very smart woman from overseas posted a great abstract about Borrelia.

The thread:

http://www.lymeneteurope.org/forum/viewtopic.php?f=7&t=812

The woman who posted it learned English by reading medical abstracts about her disease. Pretty cool, huh?!

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AliG
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I luv ya back Kel [group hug] , that's why I re-read my post, trying to figure out what I said that might have been misconstrued, and tried to clarify.

I figured something just didn't come out right.

I could tell that there was something on your nerves by the first post so I didn't really take it personally.

I must say that I've found the term "Lyme hatchlings" to be somehow grating too. I really hope that person doesn't seriously hurt himself.

It's amazing the lengths we'll go to, to find a solution that will lead to wellness. Some of us will learn new languages by reading medical abstracts(great link by the way, thanks! [Smile] ), others will ingest possibly toxic substances without fully investigating the potential damage WE may be causing ourselves.

I don't think he realizes that HE may actually cause more harm than the Bb. I guess we all get to certain levels of frustration sometimes. The desperation we may feel can be maddening when we can't easily find the answers.

Maybe he's seeing macrophages eating Bb or something. It's likely that the detergent would kill off ANY living thing. No?

Oh wait, he did say that his ND was able to confirm that he was actually looking at Bb, didn't he. Why do we have people specialized in microbiology again? That really seems like a useless profession if anyone can tell what their looking at.

All doctors should just have high-powered microscopes in their offices and treat according to what they see. It would really save the insurance companies TONS of money in the long run. We'd no longer NEED labs, phlebotomists and technicians to process our blood.

I hope he DOES find the answer without killing himself or doing permanent damage to his internal organs. I guess I'll just have to pray for him because I know people have tried reasoning. [Roll Eyes] [shake]

I'm sorry for the rambling. I don't know HOW I got off on such a tangent. I must be herxing or something.

I'm going to go back to the link you posted. She had a bunch of abstracts and I didn't get to read them all.

Thanks again! [Big Grin]
[group hug]
Ali

--------------------
Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner.

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kelmo
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I'm pretty exhausted and tired lately. Still, no excuse. Thanks for the understanding. [kiss]
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jamescase20
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actually, I have floaters too...that are dead keets BURNT into my eyes lens.

I see them in a reflection while looking though a microscope.

Interestingly, they have decreased as I txed them.

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AliG
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How did they get burnt into your eye lens?
Were you caught in a back-draft or explosion?

You couldn't "see" them unless your eyeball was under the scope.

Stop taunting Kelmo. [tsk]

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Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner.

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kelmo
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[Roll Eyes] [bonk]
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