Topic: Bartonella and malignant process in the chest of a child
Tincup
Honored Contributor (10K+ posts)
Member # 5829
posted
I dread to think how many were misdiagnosed and are still being misdiagnosed.
Eur J Pediatr. 1999 May;158(5):403-5.
Cat-scratch disease simulating a malignant process of the chest wall.
Millot F, Tailboux L, Paccalin M, Barret D, Zelinsky A, Thomas E, Levillain P, Guilhot F.
Service d'H�matologie et Oncologie M�dicale, CHU Jean Bernard, La Mil�trie, Poitiers, France. [email protected]
Cat-scratch disease is a well-known cause of regional adenopathy in immunocompetent children.
Rarely, patients may present with symptoms simulating a neoplastic disease.
The case of a 12-year-old boy with fever, swelling of the chest wall and hepatosplenic nodules is reported.
Histological analysis of biopsy specimen obtained from the chest wall lesion and the liver revealed granulomatous reaction without malignant cells.
Serological investigations were positive for Bartonella species.
The symptoms and the lesions disappeared after oral antibiotic therapy (ciprofloxacin) was started.
The patient remained symptom-free 12 months later.
CONCLUSION: The present case emphasizes the wide spectrum of clinical manifestations associated with cat-scratch disease which should be investigated as differential diagnosis of manifestations suggesting a neoplastic disease in children.
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